Collagen XIV alpha 1 Blocking Peptide | COL14A1 blocking peptide

Collagen XIV alpha 1 Blocking Peptide

Cat. Num. AAA9614981

• Gene Names: COL14A1; UND
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: Collagen XIV alpha 1; Collagen XIV alpha 1 Blocking Peptide; Collagen alpha 1(XIV) chain; Collagen type XIV alpha 1 (undulin); Collagen type XIV alpha 1; UND; Undulin (fibronectin tenascin related); Undulin; COL14A1 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for COL14A1 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for COL14A1 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 55743096
• NCBI GeneID: 7373
• NCBI Accession #: NP_066933.1
• NCBI GenBank Nucleotide #: NM_021110.3
• UniProt Accession #: Q05707; O00260; O00261; O00262; Q05708; Q5XJ18; Q96C67; Q9UDF6; B2RU07
• Molecular Weight: 193,515 Da
• NCBI Official Full Name: collagen alpha-1(XIV) chain
• NCBI Official Synonym Full Names: collagen, type XIV, alpha 1
• NCBI Official Symbol: COL14A1
• NCBI Official Synonym Symbols: UND
• NCBI Protein Information: collagen alpha-1(XIV) chain; collagen alpha-1(XIV) chain; undulin (fibronectin-tenascin-related)
• UniProt Protein Name: Collagen alpha-1(XIV) chain
• Protein Family: Collagen
• UniProt Gene Name: COL14A1
• UniProt Synonym Gene Names: UND
• UniProt Entry Name: COEA1_HUMAN

NCBI Description

This gene encodes the alpha chain of type XIV collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XIV collagen interacts with the fibril surface and is involved in the regulation of fibrillogenesis. [provided by RefSeq, Jan 2013]

Uniprot Description

COL14A1: Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors. Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Extracellular matrix; Secreted

Chromosomal Location of Human Ortholog: 8q23

Cellular Component: collagen type XIV; extracellular matrix; proteinaceous extracellular matrix; extracellular space; collagen; endoplasmic reticulum lumen; extracellular region

Molecular Function: collagen binding; protein binding, bridging; extracellular matrix structural constituent

Biological Process: collagen catabolic process; extracellular matrix disassembly; cell-cell adhesion; extracellular matrix organization and biogenesis; collagen fibril organization; homeostasis of number of cells within a tissue