ATP-dependent Clp protease ATP-binding subunit ClpX (clpX) Recombinant Protein | clpX recombinant protein

Recombinant Escherichia coli ATP-dependent Clp protease ATP-binding subunit ClpX (clpX)

Cat. Num. AAA1203135

• Gene Names: clpX; ECK0432; JW0428; lopC
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: ATP-dependent Clp protease ATP-binding subunit ClpX (clpX); Recombinant Escherichia coli ATP-dependent Clp protease ATP-binding subunit ClpX (clpX); clpX recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 2-424, full length protein
• Sequence: TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIDGQSKPLLIYGKPEAQQASGE
• Sequence Length: 423

• Species: Escherichia coli (strain K12)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 16128423
• NCBI GeneID: 945083
• NCBI Accession #: NP_414972.1
• NCBI GenBank Nucleotide #: NC_000913.3
• UniProt Accession #: P0A6H1; P33138; Q2MBY8
• Molecular Weight: 46,356 Da
• NCBI Official Full Name: ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease
• NCBI Official Symbol: clpX
• NCBI Official Synonym Symbols: ECK0432; JW0428; lopC
• NCBI Protein Information: ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease
• UniProt Protein Name: ATP-dependent Clp protease ATP-binding subunit ClpX
• Protein Family: ATP-dependent Clp protease ATP-binding
• UniProt Gene Name: clpX

NCBI Description

ClpX is an ATP-dependent molecular chaperone that serves as a substrate-specifying adapter for the ClpP serine protease in the ClpXP and ClpAXP protease complexes. [More information is available at EcoCyc: EG10159].

Uniprot Description

ATP-dependent specificity component of the Clp protease. Uses cycles of ATP binding and hydrolysis to unfold proteins and translocate them to the ClpP protease. It directs the protease to specific substrates both with and without the help of adapter proteins such as SspB. Participates in the final steps of RseA-sigma-E degradation, liberating sigma-E to induce the extracytoplasmic-stress response. It may bind to the lambda O substrate protein and present it to the ClpP protease in a form that can be recognized and readily hydrolyzed by ClpP. Can perform chaperone functions in the absence of ClpP.