Uniprot Description
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK ().
Product Notes
The clpB2 clpb2 (Catalog #
AAA1398593) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-442, Full length protein. The amino acid sequence is listed below: MHFDPNKFTV KAQEALQAAS MLASSKQNQQ IEPEHLLSVM LGDHDNIACQ IARKLETPVD TLLSVVDREI DRIPKVTGAS ATGQYISSDL GKVFDTALKE AEQLKDEYIS SEHLFIAMSE AGVKVSKLLK DAGIDRNAIL KVLTSFRGSQ RVTSQNAEES YQSLKKYSRN LNDLVIKGKL DPVIGRDDEI RRVLQILSRR TKNNPVLIGE PGVGKTAIVE GIAQRIVGGD VPENLKSKQI AALDIAALVA GTKFRGEFEE RLKALVKEVQ ASDGEVILFI DELHLLVGAG SAEGSMDAAN ILKPALARGE LRCIGATTLD EYRKHIEKDA ALERRFQTVI VDQPSVEDTV SILRGLKEKY EIHHGVRIKD AALVAAAELS NRYIADRFLP DKAIDLIDEA CSRLRLEIDS EPEELDRINR ELRRLEIERE ALKRELEATG SV.
It is sometimes possible for the material contained within the vial of
"Probable chaperone protein ClpB 2 (clpB2), Recombinant Protein" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
any time and without notice. It is the responsibility of the customer to inform AAA Biotech
of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
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