CLMP recombinant protein

CLMP, 19-235aa, Human, His-tag, Baculovirus

Cat. Num. AAA206791

• Gene Names: CLMP; ACAM; ASAM; CSBM; CSBS
• Applications: SDS-Page
• Purity: > 95% by SDS-PAGE
• Synonyms: CLMP; 19-235aa; Human; His-tag; Baculovirus; CXADR like membrane protein; ACAM; ASAM; CSBM; CSBS; CLMP recombinant protein

• Host: Baculovirus
• Purity/Purification: > 95% by SDS-PAGE
• Form/Format: Liquid. In phosphate buffered saline (pH 7.4) containing 1mM DTT, 20% glycerol.
• Concentration: 0.5 mg/ml (determined by Absorbance at 280nm) (varies by lot)
• Sequence: ADPTHTEIKR VAEEKVTLPC HHQLGLPEKD TLDIEWLLTD NEGNQKVVIT YSSRHVYNNL TEEQKGRVAF ASNFLAGDAS LQIEPLKPSD EGRYTCKVKN SGRYVWSHVI LKVLVRPSKP KCELEGELTE GSDLTLQCES SSGTEPIVYY WQRIREKEGE DERLPPKSRI DYNHPGRVLL QNLTMSYSGL YQCTAGNEAG KESCVVRVTV QYVQSIGMVA HHHHHH
• Sequence Length: 373

• Applicable Applications for CLMP recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Endotoxin Level: < 1.0 EU per 1ug of protein (determined by LAL method)
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for CLMP recombinant protein

CLMP, also known as CXADR like membrane protein, is a type 1 transmembrane protein and member of the CTX family within the immunoglobulin superfamily. This protein is highly expressed in the small intestine and placenta, and is found at intermediate levels in the heart, skeletal muscle, colon, and lung and appears in low levels in the liver and peripheral blood leukocytes as well. It is localized to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion. Also, it plays a role in adipocyte differentiation and development of obesity. Recombinant human CLMP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Categories/Family for CLMP recombinant protein

Signal Transduction; Adhesion & Movement; Cytoskeleton

References

Eguchi J., et al, (2005) Biochem J. 387:343-353.; Sze KL., et al, (2006) J Cell Physiol. 214:334-344.

NCBI and Uniprot Product Information

• NCBI GI #: 13376115
• NCBI GeneID: 79827
• NCBI Accession #: NP_079045
• NCBI GenBank Nucleotide #: NM_024769.3
• UniProt Accession #: Q9H6B4
• Molecular Weight: 25.6kDa (226aa) 28-40kDa (SDS-PAGE under reducing conditions)
• NCBI Official Full Name: CXADR-like membrane protein
• NCBI Official Synonym Full Names: CXADR like membrane protein
• NCBI Official Symbol: CLMP
• NCBI Official Synonym Symbols: ACAM; ASAM; CSBM; CSBS
• NCBI Protein Information: CXADR-like membrane protein
• UniProt Protein Name: CXADR-like membrane protein
• Protein Family: CXADR-like membrane protein
• UniProt Gene Name: CLMP
• UniProt Synonym Gene Names: ACAM; ASAM; CAR-like membrane protein

NCBI Description

This gene encodes a type I transmembrane protein that is localized to junctional complexes between endothelial and epithelial cells and may have a role in cell-cell adhesion. Expression of this gene in white adipose tissue is implicated in adipocyte maturation and development of obesity. This gene is also essential for normal intestinal development and mutations in the gene are associated with congenital short bowel syndrome. [provided by RefSeq, Aug 2015]

Uniprot Description

May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.