Serine/threonine-protein kinase chk-2 (chk-2) Recombinant Protein | chk-2 recombinant protein
Recombinant Caenorhabditis elegans Serine/threonine-protein kinase chk-2 (chk-2)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Serine/threonine-protein kinase chk-2 (chk-2); Recombinant Caenorhabditis elegans Serine/threonine-protein kinase chk-2 (chk-2); chk-2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-476, Full length
Sequence
MVRGTKRRRSSAEKPIVVVPVTRDDTMPVDEDLVVGESQCAASKPFAKLVGVRRGISSIDLADDHFVCGRGSDDAPTNFNFSQVAKDVGLYRFISKIQFSIDRDTETRRIYLHDHSRNGTLVNQEMIGKGLSRELMNGDLISIGIPALIIFVYESADADHHPEELTKKYHVTSHSLGKGGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRDIRNEVEVMKKLSHPNIVAIYDWITVAKYSYMVIEYVGGGEFFSKVVDSKYNRMGLGESLGKYFAFQLIDAILYLHSVGICHRDIKPENILCSDKAERCILKLTDFGMAKNSVNRMKTRCGTPSYNAPEIVANEGVEYTPKVDIWSLGCVLFITFSGYPPFSEEYTDMTMDEQVLTGRLIFHAQWRRITVETQNMIKWMLTVEPSNRPSAVELMSTQWMKCADCRTAKQDILKSIKPISAAAPAALQTTQAGPVKKAKM
Sequence Length
476
Species
Caenorhabditis elegans
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,338 Da
NCBI Official Full Name
Serine/threonine-protein kinase chk-2
NCBI Official Symbol
chk-2
NCBI Protein Information
Serine/threonine-protein kinase chk-2
UniProt Protein Name
Serine/threonine-protein kinase chk-2
Protein Family
UniProt Gene Name
chk-2
UniProt Synonym Gene Names
cds-1
Uniprot Description
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Phosphorylates and inhibits cdc25 phosphatase, preventing entry into mitosis. Required for nuclear reorganization and homologous chromosome pairing during meiotic prophase.
Research Articles on chk-2
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Product Notes
The chk-2 chk-2 (Catalog #AAA1295868) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-476, Full length. The amino acid sequence is listed below: MVRGTKRRRS SAEKPIVVVP VTRDDTMPVD EDLVVGESQC AASKPFAKLV GVRRGISSID LADDHFVCGR GSDDAPTNFN FSQVAKDVGL YRFISKIQFS IDRDTETRRI YLHDHSRNGT LVNQEMIGKG LSRELMNGDL ISIGIPALII FVYESADADH HPEELTKKYH VTSHSLGKGG FGKVLLGYKK SDRSVVAIKQ LNTQFSTRCS RAIAKTRDIR NEVEVMKKLS HPNIVAIYDW ITVAKYSYMV IEYVGGGEFF SKVVDSKYNR MGLGESLGKY FAFQLIDAIL YLHSVGICHR DIKPENILCS DKAERCILKL TDFGMAKNSV NRMKTRCGTP SYNAPEIVAN EGVEYTPKVD IWSLGCVLFI TFSGYPPFSE EYTDMTMDEQ VLTGRLIFHA QWRRITVETQ NMIKWMLTVE PSNRPSAVEL MSTQWMKCAD CRTAKQDILK SIKPISAAAP AALQTTQAGP VKKAKM. It is sometimes possible for the material contained within the vial of "Serine/threonine-protein kinase chk-2 (chk-2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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