CHIL3 recombinant protein

Recombinant Mouse CHIL3 Protein

Cat. Num. AAA8305227

• Gene Names: Chil3; Ym1; ECF-L; Chi3l3; AI505981
• Applications: ELISA, Western Blot, SDS-Page
• Purity: >95% as determined by reducing SDS-PAGE
• Synonyms: CHIL3; Recombinant Mouse CHIL3 Protein; Chitinase-like protein 3; Beta-N-acetylhexosaminidase Ym1; Chitinase-3-like protein 3; ECF-L; Eosinophil chemotactic cytokine; Secreted protein Ym1; Chil3; Chi3l3; Ym1; CHIL3 recombinant protein

• Host: Human Cells
• Purity/Purification: >95% as determined by reducing SDS-PAGE
• Form/Format: Lyophilized from a 0.2 mum filtered solution of PBS, pH7.4.
• Sequence: YQLMCYYTSW AKDRPIEGSF KPGNIDPCLC THLIYAFAGM QNNEITYTHE QDLRDYEALN GLKDKNTELK TLLAIGGWKF GPASFSAMVS TPQNRQIFIQ SVIRFLRQYN FDGLNLDWQY PGSRGSPPKD KHLFSVLVKE MRKAFEEESV EKDIPRLLLT STGAGIIDVI KSGYKIPELS QSLDYIQVMT YDLHDPKDGY TGENSPLYKS PYDIGKSADL NVDSIISYWK DHGAASEKLI VGFPAYGHTF ILSDPSKTGI GAPTISTGPP GKYTDESGLL AYYEVCTFLN EGATEVWDAP QEVPYAYQGN EWVGYDNVRS FKLKAQWLKD NNLGGAVVWP LDMDDFSGSF CHQRHFPLTS TLKGDLNIHS ASCKGPYVDH HHHHH
• Sequence Length: 398

• Applicable Applications for CHIL3 recombinant protein: ELISA (EIA), Western Blot (WB), SDS-PAGE
• Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
• Preparation and Storage: Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks.; Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.

Related Product Information for CHIL3 recombinant protein

Recombinant Mouse CHIL3 Protein is produced by mammalian expression system and the target gene encoding Tyr22-Tyr398 is expressed with a 6His tag at the C-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 254281348
• NCBI GeneID: 12655
• NCBI Accession #: NP_034022.2
• NCBI GenBank Nucleotide #: NP_034022.2
• UniProt Accession #: O35744
• NCBI Official Full Name: chitinase-like protein 3
• NCBI Official Synonym Full Names: chitinase-like 3
• NCBI Official Symbol: Chil3
• NCBI Official Synonym Symbols: Ym1; ECF-L; Chi3l3; AI505981
• NCBI Protein Information: chitinase-like protein 3
• UniProt Protein Name: Chitinase-like protein 3
• Protein Family: Chitinase-like protein
• UniProt Gene Name: Chil3
• UniProt Synonym Gene Names: Chi3l3; Ym1
• UniProt Entry Name: CHIL3_MOUSE

NCBI Description

The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is thought to function as a lectin and may be involved in inflammation and allergy. [provided by RefSeq, Sep 2015]

Uniprot Description

CHI3L3: Lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger. Binds chitin and heparin. Has no chitinase activity. Has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils. May play a role in inflammation and allergy. Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

Protein type: EC 3.2.1.52

Cellular Component: cytoplasm; cytoplasmic membrane-bound vesicle; endoplasmic reticulum; extracellular region; nucleus

Molecular Function: beta-N-acetylhexosaminidase activity; carbohydrate binding; chitin binding; chitinase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; hydrolase activity, hydrolyzing O-glycosyl compounds

Biological Process: carbohydrate metabolic process; chitin catabolic process; inflammatory response; metabolic process; polysaccharide catabolic process