Western Blot (WB)
(Western blotAll lanes: MMACHC antibody at 5.16 ug/mlLane 1: HepG-2 whole cell lysateLane 2: K562 whole cell lysateLane 3: A549 whole cell lysateLane 4: Hela whole cell lysateLane 5: Raji whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 32 kDaObserved band size: 32 kDa)
Rabbit anti-Human MMACHC Polyclonal Antibody | anti-MMACHC antibody
MMACHC Antibody
Western Blot (WB)
(Western blotAll lanes: MMACHC antibody at 5.16 ug/mlLane 1: HepG-2 whole cell lysateLane 2: K562 whole cell lysateLane 3: A549 whole cell lysateLane 4: Hela whole cell lysateLane 5: Raji whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 32 kDaObserved band size: 32 kDa)
Western Blot (WB)
(Western blotAll lanes: MMACHC antibody at 5.16 ug/mlLane 1: HepG-2 whole cell lysateLane 2: K562 whole cell lysateLane 3: A549 whole cell lysateLane 4: Hela whole cell lysateLane 5: Raji whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 32 kDaObserved band size: 32 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7044656 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7044656 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7044656 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7044656 at dilution of 1:100)
NCBI and Uniprot Product Information
NCBI Description
The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. [provided by RefSeq, Oct 2009]
Uniprot Description
MMACHC: May be involved in the binding and intracellular trafficking of cobalamin (vitamin B12). Defects in MMACHC are the cause of methylmalonic aciduria and homocystinuria type cblC (MMAHCC). A disorder of cobalamin metabolism characterized by decreased levels of the coenzymes adenosylcobalamin (AdoCbl) and methylcobalamin (MeCbl). Affected individuals may have developmental, hematologic, neurologic, metabolic, ophthalmologic, and dermatologic clinical findings. Although considered a disease of infancy or childhood, some individuals develop symptoms in adulthood. Belongs to the MMACHC family.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: cytosol
Molecular Function: cyanocobalamin reductase (cyanide-eliminating) activity; oxidoreductase activity; protein binding
Biological Process: cobalamin metabolic process
Disease: Methylmalonic Aciduria And Homocystinuria, Cblc Type
Research Articles on MMACHC
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Product Notes
The MMACHC mmachc (Catalog #AAA7044656) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMACHC Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MMACHC can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the MMACHC mmachc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMACHC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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