Chicken FAIM3 ELISA Kit | FAIM3 elisa kit

Chicken FAIM3 (Fas Apoptotic Inhibitory Molecule 3) ELISA Kit

Cat. Num. AAA2512039

• Gene Names: FAIM3; FCMR; TOSO
• Reactivity: Chicken
• Synonyms: FAIM3; Chicken FAIM3 (Fas Apoptotic Inhibitory Molecule 3) ELISA Kit; FAIM3 elisa kit

• Reactivity: Chicken
• Specificity: This kit recognizes natural and recombinant Chicken FAIM3. No significant cross-reactivity or interference between Chicken FAIM3 and analogues was observed.
• Sequence Length: 306

• Samples: Serum, Plasma, Biological Fluids
• Assay Type: Sandwich
• Detection Range: 0.156-10ng/mL
• Sensitivity: Min: 0.094ng/mL; Max: 10ng/mL
• Preparation and Storage: Store at 4 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for FAIM3 elisa kit

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Chicken FAIM3 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to FAIM3. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for FAIM3 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain FAIM3, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of FAIM3. You can calculate the concentration of FAIM3 in the samples by comparing the OD of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 301069341
• NCBI GeneID: 9214
• NCBI Accession #: NP_001180267.1
• NCBI GenBank Nucleotide #: NM_001193338.1
• UniProt Accession #: O60667; A8K7J2; B7Z6Z0; D9MWM3
• Molecular Weight: 33,828 Da
• NCBI Official Full Name: fas apoptotic inhibitory molecule 3 isoform c
• NCBI Official Synonym Full Names: Fas apoptotic inhibitory molecule 3
• NCBI Official Symbol: FAIM3
• NCBI Official Synonym Symbols: FCMR; TOSO
• NCBI Protein Information: fas apoptotic inhibitory molecule 3; Fc mu receptor; IgM Fc receptor; immunoglobulin mu Fc receptor; regulator of Fas-induced apoptosis Toso
• UniProt Protein Name: Fas apoptotic inhibitory molecule 3
• UniProt Gene Name: FAIM3
• UniProt Synonym Gene Names: TOSO
• UniProt Entry Name: FAIM3_HUMAN

NCBI Description

Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]

Uniprot Description

FAIM3: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Apoptosis

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: extracellular region; integral to membrane

Biological Process: immune system process; cellular defense response; negative regulation of apoptosis