Chicken Coronin-1A (CORO1A) ELISA Kit | CORO1A elisa kit

Chicken Coronin-1A (CORO1A) ELISA Kit

Cat. Num. AAA7219960

• Gene Names: CORO1A; p57; IMD8; TACO; CLABP; HCORO1; CLIPINA
• Reactivity: Chicken
• Synonyms: Coronin-1A (CORO1A); Chicken Coronin-1A (CORO1A) ELISA Kit; CORO1A elisa kit

• Reactivity: Chicken

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Preparation and Storage: Store all reagents at 2-8 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 300934762
• NCBI GeneID: 11151
• NCBI Accession #: NP_001180262.1
• NCBI GenBank Nucleotide #: NM_001193333.2
• Molecular Weight: 51,026 Da
• NCBI Official Full Name: coronin-1A
• NCBI Official Synonym Full Names: coronin, actin binding protein, 1A
• NCBI Official Symbol: CORO1A
• NCBI Official Synonym Symbols: p57; IMD8; TACO; CLABP; HCORO1; CLIPINA
• NCBI Protein Information: coronin-1A; clipin-A; coronin-like protein A; coronin-like protein p57; tryptophan aspartate-containing coat protein
• UniProt Protein Name: Coronin-1A
• Protein Family: Coronin
• UniProt Gene Name: CORO1A
• UniProt Synonym Gene Names: CORO1; Clipin-A; TACO
• UniProt Entry Name: COR1A_HUMAN

NCBI Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16. [provided by RefSeq, Sep 2010]

Uniprot Description

coronin 1A: May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. Belongs to the WD repeat coronin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: cortical actin cytoskeleton; protein complex; early endosome; immunological synapse; actin filament; intercellular junction; phagocytic vesicle; phagocytic vesicle membrane; membrane; axon; lamellipodium; cytoplasm; plasma membrane; nucleus; phagocytic cup

Molecular Function: actin filament binding; protein C-terminus binding; protein binding; protein homodimerization activity; cytoskeletal protein binding; phosphoinositide 3-kinase binding

Biological Process: negative regulation of vesicle fusion; leukocyte chemotaxis; actin filament organization; cell-substrate adhesion; phagocytosis; regulation of release of sequestered calcium ion into cytosol; uropod organization and biogenesis; phagolysosome formation; regulation of cell shape; regulation of actin filament polymerization; positive chemotaxis; homeostasis of number of cells within a tissue; calcium ion transport; negative regulation of actin nucleation; innate immune response; T cell homeostasis; positive regulation of T cell proliferation; negative regulation of neuron apoptosis; actin cytoskeleton organization and biogenesis; cell motility; positive regulation of cell migration

Disease: Immunodeficiency 8