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Centrosomal Protein 57kDa (CEP57) Recombinant Protein | CEP57 recombinant protein

Recombinant Centrosomal Protein 57kDa (CEP57)

Gene Names
CEP57; MVA2; PIG8; TSP57
Applications
SDS-Page, Western Blot
Purity
> 90%
Synonyms
Centrosomal Protein 57kDa (CEP57); Recombinant Centrosomal Protein 57kDa (CEP57); PIG8; TSP57; Translokin; FGF2-interacting protein; Testis-specific protein 57; CEP57 recombinant protein
Ordering
 
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For Research Use Only!
Host
Host: E Coli
Source: Prokaryotic Expression
Purity/Purification
> 90%
Form/Format
Freeze-Dried Powder; PBS, pH7.4, Containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Sequence Positions
Lys346~Tyr500
Sequence Length
500
Applicable Applications for CEP57 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Species
Mouse
Tag
N-terminal His-Tag
Isoelectric Point
8.5
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Subcellular Location
Secreted
Reconstitution
Reconstitute in PBS or others.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for CEP57 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
Predicted MW: 21.3kDa
Accurate MW: 23kDa
NCBI Official Full Name
Centrosomal protein 57kDa
NCBI Official Synonym Full Names
centrosomal protein 57
NCBI Official Symbol
CEP57
NCBI Official Synonym Symbols
MVA2; PIG8; TSP57
NCBI Protein Information
centrosomal protein of 57 kDa
Protein Family

NCBI Description

This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Research Articles on CEP57

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Product Notes

The CEP57 (Catalog #AAA2105537) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Lys346~Tyr500. AAA Biotech's Centrosomal Protein 57kDa (CEP57) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the CEP57 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Centrosomal Protein 57kDa (CEP57), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.
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