Human Cyclin Dependent Kinase Inhibitor 3 (CDKN3) ELISA Kit | CDKN3 elisa kit

Human Cyclin Dependent Kinase Inhibitor 3 (CDKN3) ELISA Kit

Cat. Num. AAA451903

• Gene Names: CDKN3; KAP; CDI1; CIP2; KAP1
• Reactivity: Human
• Synonyms: Cyclin Dependent Kinase Inhibitor 3 (CDKN3); Human Cyclin Dependent Kinase Inhibitor 3 (CDKN3) ELISA Kit; CDI1; CIP2; KAP1; CDK2-Associated Dual Specificity Phosphatase; Kinase Associated Phosphatase; Cyclin-dependent kinase interactor 1; Cyclin-dependent kinase-interacting 2; CDKN3 elisa kit

• Reactivity: Human
• Sequence Length: 172

• Samples: Tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.156-10ng/mL
• Sensitivity: 0.053ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 195927025
• NCBI GeneID: 1033
• NCBI Accession #: NP_001124323.1
• NCBI GenBank Nucleotide #: NM_001130851.1
• UniProt Accession #: Q16667; Q53ZU6; Q5U0M4; Q6P1N8; Q99585; Q9BPW7; Q9BY36; Q9C042; Q9C046; Q9C047; Q9C049; Q9C051
• Molecular Weight: 19,359 Da
• NCBI Official Full Name: cyclin-dependent kinase inhibitor 3 isoform 2
• NCBI Official Synonym Full Names: cyclin dependent kinase inhibitor 3
• NCBI Official Symbol: CDKN3
• NCBI Official Synonym Symbols: KAP; CDI1; CIP2; KAP1
• NCBI Protein Information: cyclin-dependent kinase inhibitor 3
• UniProt Protein Name: Cyclin-dependent kinase inhibitor 3
• Protein Family: Cyclin-dependent kinase inhibitor
• UniProt Gene Name: CDKN3
• UniProt Synonym Gene Names: CDI1; CIP2; KAP

NCBI Description

The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Uniprot Description

May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.