ZRSR2 cdna clone

ZRSR2 cDNA Clone

Cat. Num. AAA1268474

• Gene Names: ZRSR2; URP; ZC3H22; U2AF1L2; U2AF1RS2; U2AF1-RS2
• Synonyms: ZRSR2; ZRSR2 cDNA Clone; ZRSR2 cdna clone

• Sequence: ATGGCTGCGCCCGAGAAGATGACGTTTCCCGAGAAACCAAGCCACAAAAAGTACAGGGCCGCCCTGAAGAAGGAGAAACGAAAGAAACGTCGGCAGGAACTTGCTCGACTGAGAGACTCAGGACTCTCACAGAAGGAGGAAGAGGAGGACACTTTTATTGAAGAACAACAACTAGAAGAAGAGAAGCTATTGGAAAGAGAGAGGCAAAGATTACATGAGGAGTGGTTGCTAAGAGAGCAGAAGGCACAAGAAGAATTCAGAATAAAGAAGGAAAAGGAAGAGGCGGCTAAAAAACGGCAAGAAGAACAAGAGAGAAAGTTAAAGGAACAATGGGAAGAACAGCAGAGGAAAGAGAGAGAAGAGGAGGAGCAGAAACGACAGGAGAAGAAAGAAAAAGAGGAAGCTTTGCAGAAGATGCTGGATCAGGCTGAAAATGAGTTGGAAAATGGTACCACATGGCAAAACCCAGAACCACCCGTGGATTTCAGAGTAATGGAGAAGGATCGAGCTAATTGTCCCTTCTACAGTAAAACAGGAGCTTGCAGATTTGGAGATAGATGTTCACGTAAACATAATTTCCCAACATCCAGTCCTACCCTTCTTATTAAGAGCATGTTTACGACGTTTGGAATGGAGCAGTGCAGGAGGGATGACTATGACCCTGACGCAAGCCTGGAGTACAGCGAGGAAGAAACCTACCAACAGTTCCTAGACTTCTATGAGGATGTGTTGCCCGAGTTCAAGAACGTGGGGAAAGTGATTCAGTTCAAGGTCAGCTGCAATTTGGAACCTCACCTGAGGGGCAATGTATATGTTCAGTACCAGTCGGAAGAAGAATGCCAAGCAGCCCTTTCTCTGTTTAACGGACGATGGTATGCAGGACGACAGCTGCAGTGTGAATTCTGCCCCGTGACCCGGTGGAAAATGGCGATTTGTGGTTTATTTGAAATACAACAATGTCCAAGAGGAAAGCACTGCAACTTTCTTCATGTGTTCAGAAATCCCAACAATGAATTCTGGGAAGCTAATAGAGACATCTACTTGTCTCCAGATCGGACTGGCTCCTCCTTTGGGAAGAACTCCGAAAGGAGGGAGAGGATGGGCCACCACGACGACTACTACAGCAGGCTGCGGGGAAGGAGAAACCCTAGTCCAGACCACTCCTACAAAAGAAATGGGGAATCCGAGAGGAAAAGTAGTCGTCACAGGGGGAAGAAATCTCACAAACGCACATCAAAGAGTCGGGAGAGGCACAATTCACGAAGCAGAGGAAGAAATAGGGACCGCAGCAGGGACCGCAGCCGGGGCCGGGGCAGCCGGAGCCGGAGCCGGAGCCGGAGCCGCAGGAGCCGCCGCAGCCGGAGCCAAAGTTCCTCTAGGTCCCGAAGTCGTGGCAGGAGGAGGTCGGGTAATAGAGACAGAACTGTTCAGAGTCCCAAATCCAAATAA
• Sequence Length: 1449

• Vector: Please Inquire

NCBI and Uniprot Product Information

• NCBI GI #: 109731266
• NCBI GeneID: 8233
• Molecular Weight: 58,045 Da
• NCBI Official Full Name: Homo sapiens zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2, mRNA
• NCBI Official Synonym Full Names: zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
• NCBI Official Symbol: ZRSR2
• NCBI Official Synonym Symbols: URP; ZC3H22; U2AF1L2; U2AF1RS2; U2AF1-RS2
• NCBI Protein Information: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
• UniProt Protein Name: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
• Protein Family: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein
• UniProt Gene Name: ZRSR2
• UniProt Synonym Gene Names: U2AF1-RS2; U2AF1L2; U2AF1RS2; URP; URP
• UniProt Entry Name: U2AFM_HUMAN

NCBI Description

This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008]

Uniprot Description

ZRSR2: Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3'-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP- dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.

Protein type: RNA splicing

Chromosomal Location of Human Ortholog: Xp22.1

Cellular Component: U12-dependent spliceosome

Molecular Function: pre-mRNA 3'-splice site binding; protein binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; spliceosome assembly