URM1 cdna clone
URM1 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
URM1: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo. Belongs to the URM1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin-like modifier; Transferase
Chromosomal Location of Human Ortholog: 9q34.11
Cellular Component: cytosol
Molecular Function: sulfurtransferase activity; protein binding
Biological Process: protein urmylation; tRNA wobble uridine modification
Research Articles on URM1
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Product Notes
The URM1 urm1 (Catalog #AAA1272823) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggctgcgc ccttgtcagt ggaggtggag ttcggaggtg gtgcggagct cctgtttgac ggtattaaga aacatcgagt cactttgcct ggacaggagg aaccctggga catccggaac ctgctcatct ggatcaagaa gaatttgcta aaagagcggc cagagttgtt catccaggga gacagcgtgc ggccaggaat tctggtgctg attaacgatg ccgactggga gctactgggt gagctggact accagcttca ggaccaggac agcgtcctct tcatctccac tctgcacggc ggctga. It is sometimes possible for the material contained within the vial of "URM1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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