UBR7 cdna clone
UBR7 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul 2016]
Uniprot Description
UBR7: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Protein type: Ubiquitin ligase; Ubiquitin conjugating system; EC 6.3.2.19; EC 6.3.2.-; Ligase
Chromosomal Location of Human Ortholog: 14q32.12
Research Articles on UBR7
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Product Notes
The UBR7 ubr7 (Catalog #AAA1268072) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGAGGCGTG CGCTGTCCTG GGCGGCAGCG ACTCCGAGAA GTGCTCCTAC TCTCAGAAAT TTTCGTTGTG ATTGTGGAAA CAGCAAGTTT AAAAATTTGG AATGCAAATT ACTTCCTGAC AAAGCAAAGG TAAATTCTGG CAATAAGTAC AATGACAACT TTTTTGGATT GTACTGCATT TGCAAGAGAC CTTATCCTGA TCCTGAAGAC GAGATTCCAG ATGAGATGAT CCAGTGCGTA GTCTGTGAAG ACTGGTTCCA TGGAAGGCAT CTTGGTGCCA TTCCCCCTGA GAGTGGGGAT TTTCAGGAGA TGGTATGCCA GGCCTGCATG AAACGTTGTT CTTTTTTGTG GGCTTATGCT GCACAATTGG CAGTAACCAA AATATCCACT GAGGATGATG GATTGGTGCG GAACATTGAT GGAATAGGTG ATCAGGAAGT TATCAAACCT GAAAATGGAG AGCATCAAGA TAGTACCCTC AAAGAGGATG TTCCAGAACA GGGAAAGGAT GATGTCCGGG AGGTTAAAGT AGAGCAGAAC AGTGAACCAT GTGCCGGCTC TAGTTCTGAA TCTGATCTCC AGACAGTGTT TAAGAATGAA AGCCTCAACG CAGAATCAAA ATCTGGCTGC AAACTTCAGG AGCTTAAAGC TAAGCAGCTT ATAAAGAAAG ACACTGCCAC CTATTGGCCC CTGAACTGGC GTAGCAAGTT GTGTACCTGC CAAGACTGTA TGAAAATGTA TGGAGATCTA GATGTCTTAT TCCTGACAGA TGAATACGAC ACAGTTCTGG CTTATGAAAA CAAAGGGAAG ATTGCCCAGG CCACTGACAG GAGCGATCCC CTAATGGATA CCCTTAGCAG CATGAATAGA GTCCAGCAAG TGGAACTCAT TTGTGAATAC AATGATTTGA AGACTGAACT TAAAGACTAT CTCAAGAGAT TTGCTGATGA AGGCACGGTT GTTAAGAGAG AGGACATTCA GCAGTTCTTT GAAGAGTTTC AGTCAAAAAA AGAGAAGAAG AGTGGATGGG ATGCAGTATT ACTGCAGCTA GAGTGGAGTA TGAAGCTTTC TCATTCAAGC CAATGA. It is sometimes possible for the material contained within the vial of "UBR7, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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