Western Blot (WB)
(Western Blot analysis of UBR7 in Hela cell lysate using UBR7 Rabbit pAb at dilution 1/300)
Rabbit anti-Human, Mouse UBR7 Polyclonal Antibody | anti-UBR7 antibody
UBR7 Rabbit pAb
Gene Names
UBR7; C14orf130
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
UBR7; Polyclonal Antibody; UBR7 Rabbit pAb; ubiquitin protein ligase E3 component n-recognin 7 (putative); C14orf130; anti-UBR7 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.4mg/ml (varies by lot)
Applicable Applications for anti-UBR7 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
IHC-P: 1:30-1:150
IHC-P: 1:30-1:150
Immunogen
Fusion protein of human UBR7
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Western Blot analysis of UBR7 in Hela cell lysate using UBR7 Rabbit pAb at dilution 1/300)
Western Blot (WB)
(Western Blot analysis of UBR7 in Hela cell lysate using UBR7 Rabbit pAb at dilution 1/300)
Immunohistochemistry (IHC)
(Immunohistochemistry of UBR7 in paraffin-embedded Human colorectal cancer tissue using UBR7 Rabbit pAb at dilution 1/30. Predicted cell location: Nucleus)
Immunohistochemistry (IHC)
(Immunohistochemistry of UBR7 in paraffin-embedded Human colorectal cancer tissue using UBR7 Rabbit pAb at dilution 1/30. Predicted cell location: Nucleus)
Related Product Information for anti-UBR7 antibody
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr7 (ubiquitin protein ligase E3 component n-recognin 7), also known as C14orf130 or N-recognin-7, is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,999 Da
NCBI Official Full Name
putative E3 ubiquitin-protein ligase UBR7
NCBI Official Synonym Full Names
ubiquitin protein ligase E3 component n-recognin 7 (putative)
NCBI Official Symbol
UBR7
NCBI Official Synonym Symbols
C14orf130
NCBI Protein Information
putative E3 ubiquitin-protein ligase UBR7; N-recognin-7
UniProt Protein Name
Putative E3 ubiquitin-protein ligase UBR7
Protein Family
UniProt Gene Name
UBR7
UniProt Synonym Gene Names
C14orf130
UniProt Entry Name
UBR7_HUMAN
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Product Notes
The UBR7 ubr7 (Catalog #AAA4760256) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UBR7 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's UBR7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC-P: 1:30-1:150. Researchers should empirically determine the suitability of the UBR7 ubr7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UBR7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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