TCEB3 cdna clone
TCEB3 cDNA Clone
Gene Names
TCEB3; EloA; SIII; TCEB3A; SIII p110
Synonyms
TCEB3; TCEB3 cDNA Clone; TCEB3 cdna clone
Sequence
atggcggcggagtcggcgctccaagttgtggagaagctgcaggcgcgcctggccgcgaacccggaccctaagaagctattgaaatatttgaagaaactctccaccctgcctattacagtagacattcttgcggagactggggttgggaaaacagtaaatagcttgcgaaaacacgagcatgttggaagctttgccagggacctagtggcccagtggaagaagctggttcctgtggaacgaaatgctgagcctgatgaacaggactttgagaagagcaattcccgaaagcgccctcgggatgccctgcagaaggaggaggagatggagggggactaccaagaaacctggaaagccacggggagccgatcctatagccctgaccacaggcagaagaaacataggaaactctcggagctcgagagacctcacaaagtgtctcacggtcatgagaggagagatgagagaaagaggtgtcacagaatgtcaccaacttactcttcagaccctgagtcttctgattatggccatgttcaatcccctccatcttgtaccagtcctcatcagatgtacgtcgaccactacagatccctggaggaggaccaggagcccattgtttcacaccagaagcctgggaaaggccacagcaatgcctttcaggacagactcggggccagccaagaacgacacctgggtgaaccccatgggaaaggggttgtgagtcaaaacaaggagcacaaatcttcccacaaggacaaacgccccgtggatgccaagagtgatgagaaggcctctgtggtgagcagagagaaatcacacaaggccctctccaaagaggagaaccgaaggccaccctcaggggacaatgcaagggagaaaccgccctctagtggcgtaaagaaagagaaggacagagagggcagcagcctgaagaagaagtgtttgcctccctcagaggccgcttcagacaaccacctgaaaaagccaaagcacagagacccagagaaagccaaattggacaaaagcaagcaaggtctggacagctttgacacaggaaaaggagcaggagacctgttgcccaaggtaaaagagaagggttctaacaacctaaagactccagaagggaaagtcaaaactaatttggatagaaagtcactgggctccctccctaaagttgaggagacagatatggaggatgaattcgagcagccaaccatgtcttttgaatcctacctcagctatgaccagccccggaagaaaaagaaaaagattgtgaaaacttcagccacggcacttggagataaaggacttaaaaaaaatgactctaaaagcactggtaaaaacttggactcagttcagaaattacccaaggtgaacaaaaccaagtcagagaagccggctggagctgatttagccaagctgagaaaggtgcctgatgtgttgccagtgttgccagacctcccgttacccgcgatacaggccaattaccgtccactgccttccctcgagctgatatcctccttccagccaaagcgaaaagcgttctcttcaccccaggaagaagaagaagctggatttactgggcgcagaatgaattccaagatgcaggtgtattctggttccaagtgtgcctatctccctaaaatgatgaccttgcaccagcaatgcatccgagtacttaaaaacaacatcgattcaatctttgaagtgggaggagtcccatactctgttcttgaacccgttttggagaggtgtacacctgatcagctgtatcgcatagaggaatacaatcatgtattaattgaagaaacagatcaattatggaaagttcattgtcaccgagactttaaggaagaaagacccgaagagtatgagtcgtggcgagagatgtacctgcggcttcaggacgcccgagagcagcggctacgagtactaacaaagaatatccagttcgcacatgccaataagcccaaaggccgacaagcaaagatggcctttgtcaactctgtggccaagccacctcgtgacgtccggaggaggcaggaaaagtttggaacgggaggagcagctgtccctgagaaaatcaagatcaagccagccccgtaccccatgggaagcagccatgcttccgccagtagtatcagctttaaccccagccctgaggagccggcctatgatggcccaagcaccagcagtgcccacttggcaccagtggtcagcagcactgtttcctatgatcctaggaaacccactgtgaagaaaattgccccaatgatggccaagacaattaaagctttcaagaacagattctcccgacgataa
Sequence Length
2319
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
89,909 Da
NCBI Official Full Name
Homo sapiens transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A), mRNA
NCBI Official Synonym Full Names
transcription elongation factor B subunit 3
NCBI Official Symbol
TCEB3
NCBI Official Synonym Symbols
EloA; SIII; TCEB3A; SIII p110
NCBI Protein Information
transcription elongation factor B polypeptide 3
UniProt Protein Name
Transcription elongation factor B polypeptide 3
Protein Family
UniProt Gene Name
TCEB3
UniProt Synonym Gene Names
EloA
UniProt Entry Name
ELOA1_HUMAN
NCBI Description
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq, Jul 2008]
Uniprot Description
TCEB3: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). Heterotrimer of an A (A1, A2 or A3), B and C subunit. The C subunit mediates the binding of the elongin BC complex to subunit A.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 1p36.1
Cellular Component: extracellular space; nucleoplasm
Molecular Function: protein binding
Biological Process: RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Research Articles on TCEB3
Similar Products
Product Notes
The TCEB3 tceb3 (Catalog #AAA1269142) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcggcgg agtcggcgct ccaagttgtg gagaagctgc aggcgcgcct ggccgcgaac ccggacccta agaagctatt gaaatatttg aagaaactct ccaccctgcc tattacagta gacattcttg cggagactgg ggttgggaaa acagtaaata gcttgcgaaa acacgagcat gttggaagct ttgccaggga cctagtggcc cagtggaaga agctggttcc tgtggaacga aatgctgagc ctgatgaaca ggactttgag aagagcaatt cccgaaagcg ccctcgggat gccctgcaga aggaggagga gatggagggg gactaccaag aaacctggaa agccacgggg agccgatcct atagccctga ccacaggcag aagaaacata ggaaactctc ggagctcgag agacctcaca aagtgtctca cggtcatgag aggagagatg agagaaagag gtgtcacaga atgtcaccaa cttactcttc agaccctgag tcttctgatt atggccatgt tcaatcccct ccatcttgta ccagtcctca tcagatgtac gtcgaccact acagatccct ggaggaggac caggagccca ttgtttcaca ccagaagcct gggaaaggcc acagcaatgc ctttcaggac agactcgggg ccagccaaga acgacacctg ggtgaacccc atgggaaagg ggttgtgagt caaaacaagg agcacaaatc ttcccacaag gacaaacgcc ccgtggatgc caagagtgat gagaaggcct ctgtggtgag cagagagaaa tcacacaagg ccctctccaa agaggagaac cgaaggccac cctcagggga caatgcaagg gagaaaccgc cctctagtgg cgtaaagaaa gagaaggaca gagagggcag cagcctgaag aagaagtgtt tgcctccctc agaggccgct tcagacaacc acctgaaaaa gccaaagcac agagacccag agaaagccaa attggacaaa agcaagcaag gtctggacag ctttgacaca ggaaaaggag caggagacct gttgcccaag gtaaaagaga agggttctaa caacctaaag actccagaag ggaaagtcaa aactaatttg gatagaaagt cactgggctc cctccctaaa gttgaggaga cagatatgga ggatgaattc gagcagccaa ccatgtcttt tgaatcctac ctcagctatg accagccccg gaagaaaaag aaaaagattg tgaaaacttc agccacggca cttggagata aaggacttaa aaaaaatgac tctaaaagca ctggtaaaaa cttggactca gttcagaaat tacccaaggt gaacaaaacc aagtcagaga agccggctgg agctgattta gccaagctga gaaaggtgcc tgatgtgttg ccagtgttgc cagacctccc gttacccgcg atacaggcca attaccgtcc actgccttcc ctcgagctga tatcctcctt ccagccaaag cgaaaagcgt tctcttcacc ccaggaagaa gaagaagctg gatttactgg gcgcagaatg aattccaaga tgcaggtgta ttctggttcc aagtgtgcct atctccctaa aatgatgacc ttgcaccagc aatgcatccg agtacttaaa aacaacatcg attcaatctt tgaagtggga ggagtcccat actctgttct tgaacccgtt ttggagaggt gtacacctga tcagctgtat cgcatagagg aatacaatca tgtattaatt gaagaaacag atcaattatg gaaagttcat tgtcaccgag actttaagga agaaagaccc gaagagtatg agtcgtggcg agagatgtac ctgcggcttc aggacgcccg agagcagcgg ctacgagtac taacaaagaa tatccagttc gcacatgcca ataagcccaa aggccgacaa gcaaagatgg cctttgtcaa ctctgtggcc aagccacctc gtgacgtccg gaggaggcag gaaaagtttg gaacgggagg agcagctgtc cctgagaaaa tcaagatcaa gccagccccg taccccatgg gaagcagcca tgcttccgcc agtagtatca gctttaaccc cagccctgag gagccggcct atgatggccc aagcaccagc agtgcccact tggcaccagt ggtcagcagc actgtttcct atgatcctag gaaacccact gtgaagaaaa ttgccccaat gatggccaag acaattaaag ctttcaagaa cagattctcc cgacgataa. It is sometimes possible for the material contained within the vial of "TCEB3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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