TAF9B cdna clone
TAF9B cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process. [provided by RefSeq, Jul 2008]
Uniprot Description
TAF9B: Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription. Belongs to the TAF9 family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: Xq13.1-q21.1
Cellular Component: nucleoplasm; transcription factor TFIID complex
Molecular Function: protein binding; transcription corepressor activity
Biological Process: negative regulation of apoptosis; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell growth; protein stabilization; RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter
Research Articles on TAF9B
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Product Notes
The TAF9B taf9b (Catalog #AAA1270003) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggagtcgg gcaagatggc gcctcccaag aacgctccga gagatgcctt ggtgatggca cagatcctga aggatatggg aatcacagag tatgaaccaa gggttataaa tcaaatgttg gaatttgctt tccgttatgt gactacaatt ctggatgatg caaaaattta ttcgagccat gctaagaaac ctaatgttga tgcagatgat gtgagactgg caatccagtg tcgtgctgac caatctttta cctctcctcc cccaagagat tttttactgg atatcgcaag gcagaaaaat caaacccctt tgccactgat taagccatat gcaggaccta gactgccacc tgatagatac tgcttaacag ctccaaacta taggctgaag tccttaatta aaaagggacc taaccaaggg agactagttc cacgattaag tgttggtgct gttagtagca aacctactac tcctactata gcaaccccac aaacggtgtc tgtcccaaat aaagttgcaa ctccaatgtc agtgacaagc caaagattta cggtgcagat tccaccttct cagtccacac ctgtcaaacc agttcctgca acaactgcag ttcaaaatgt tctgattaat ccttcaatga ttgggcccaa aaatattctt attaccacca acatggtttc gtcacagaac acagccaatg aagcaaaccc actgaagaga aaacatgaag atgatgatga caatgatatt atgtaa. It is sometimes possible for the material contained within the vial of "TAF9B, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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