Rabbit MT-ND2 Polyclonal Antibody | anti-MT-ND2 antibody

MT-ND2 Polyclonal Antibody

Cat. Num. AAA3006447

• Gene Names: MT-ND2; MTND2; ND2
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: MT-ND2; Polyclonal Antibody; MT-ND2 Polyclonal Antibody; NADH-ubiquinone oxidoreductase chain 2; NADH dehydrogenase subunit 2; MTND2; NADH2; ND2; anti-MT-ND2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: MT-ND2 polyclonal antibody detects endogenous levels of MT-ND2 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 347

• Applicable Applications for anti-MT-ND2 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human MT-ND2.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of MT-ND2 pAb at 1:1000 dilutionLane1:LOVO whole cell lysate (30ug) Lane2:L02 whole cell lysate (30ug) Lane3:The Heart tissue lysate of Mouse (40ug) Lane4:The Kidney tissue lysate of Rat (40ug) Lane5:H9C2 whole cell lysate (40ug) Lane6:CT26 whole cell lysate (40ug) Lane7:SGC7901 whole cell lysate (40ug))

Related Product Information for anti-MT-ND2 antibody

MT-ND2: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND2 are a cause of Leber hereditary optic neuropathy (LHON). LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes. Defects in MT-ND2 may be associated with susceptibility to Alzheimer disease mitochondrial (AD-MT).

NCBI and Uniprot Product Information

• NCBI GI #: 251831108
• NCBI GeneID: 4536
• NCBI Accession #: YP_003024027.1
• NCBI GenBank Nucleotide #: YP_003024027.1
• UniProt Accession #: P03891
• Molecular Weight: ~ 39kDa
• NCBI Official Full Name: NADH dehydrogenase subunit 2 (mitochondrion)
• NCBI Official Synonym Full Names: mitochondrially encoded NADH dehydrogenase 2
• NCBI Official Symbol: MT-ND2
• NCBI Official Synonym Symbols: MTND2; ND2
• NCBI Protein Information: MTND2
• UniProt Protein Name: NADH-ubiquinone oxidoreductase chain 2
• Protein Family: NADH-ubiquinone oxidoreductase
• UniProt Gene Name: MT-ND2
• UniProt Synonym Gene Names: MTND2; NADH2; ND2
• UniProt Entry Name: NU2M_HUMAN