SUPT5H cdna clone
SUPT5H cDNA Clone
Gene Names
SUPT5H; SPT5; SPT5H; Tat-CT1
Synonyms
SUPT5H; SUPT5H cDNA Clone; SUPT5H cdna clone
Sequence
atgtcggacagcgaggacagcaacttttccgaggaggaggacagcgagcgcagcagtgacggcgaggaggccgaggtagacgaagagcggcggagtgcagcgggcagtgagaaagaagaagagcctgaggacgaagaggaggaggaagaggaggaggaatatgatgaggaagaggaagaagaagatgatgaccgaccccccaagaaaccccgccatggaggcttcattctggacgaggctgatgttgacgatgagtatgaggacgaggaccagtgggaggatggagcagaggacattctagagaaagaagagattgaagcctccaatatcgataatgttgtcctggatgaagatcgttctggggctcgccgcctgcaaaacctctggagggaccagcgagaagaagaactgggcgagtattacatgaagaaatacgccaagtcatctgtgggagagacggtgtatggaggatctgatgagctctcagacgacatcacccagcagcagctgctcccaggagtcaaggatcccaatctgtggactgtcaaatgtaagattggggaggaacgggccacggccatttccttgatgcgcaagttcattgcctaccagttcacagacacgcccctgcagatcaagtcagtagtggcaccagagcatgtgaagggctacatctacgtggaggcctacaagcagacccacgtgaagcaggccattgagggggtgggcaacctgcggcttggctactggaaccagcagatggtgcccatcaaggagatgacagacgtgctcaaagtggtgaaggaggtggccaacctgaaaccaaagtcctgggtccgcctcaagcggggcatctacaaggatgacattgctcaggtggactacgtggagcccagccagaacaccatctccctgaagatgatcccacgcatcgactacgatcgcatcaaggcccgcatgagcttgaaagactggtttgccaaaaggaagaagtttaagcggcctccacagaggctgtttgatgctgagaagatcaggtccctggggggtgatgttgcctctgatggtgacttcctcatctttgaggggaaccgttacagccggaagggctttctgttcaagagcttcgccatgtctgctgtgatcacggagggtgtgaagccaacactctctgagctggaaaagtttgaggaccagccagagggcattgacctggaggtggtgactgagagcacagggaaggagcgggagcacaacttccaacctggggacaacgtggaggtctgtgagggtgagctcatcaacctgcagggcaagatcctcagcgtggatggcaacaagatcaccatcatgcccaagcatgaggacctcaaggacatgttggagttcccagcccaggaacttagaaaatacttcaagatgggggaccacgtgaaggtgattgctggccgattcgagggcgacacaggcctcattgtgcgggtggaggagaatttcgttatcctgttctctgacctcaccatgcatgagctgaaggtgctcccccgggacctgcagctctgctcagagacagcatcaggtgtggatgttgggggccagcatgaatggggcgagctggtgcagctggatccccagactgtgggtgtcatcgtgcgactagaacgggagaccttccaggtgctgaacatgtacgggaaggtggtgactgtcagacatcaggctgtgacccggaagaaggacaaccgctttgctgtggccttggactcagagcagaacaacatccatgtgaaagacatcgttaaggtcattgatggcccccactcaggccgagaaggggagattcgccatctcttccgaagcttcgccttcctacattgcaagaaactggtggagaacgggggcatgtttgtctgcaagacccgccacctggtgctggctgggggctcaaagccccgtgatgtgaccaacttcaccgtgggtggctttgcgcctatgagtccccggatcagcagccccatgcaccccagtgctggaggtcagcgtggcggctttggtagcccaggtggcggcagtggtggcatgagcaggggccggggccggagggacaacgaactcatcggccagaccgtgcgcatctcccaggggccctacaaaggctacatcggtgtggtgaaagatgccacagagtccacggcccgtgtggagctgcactccacctgccagaccatctctgtggaccgtcagcggctcaccacggtgggctcacggcgcccgggcggcatgacctcgacctatgggaggacgcccatgtatggctcccagacgcccatgtatggctctggctcccgaacacccatgtacggctcacagacacccctccaggatggtagccgcaccccacactacggctcacagacgcccctgcatgatggcagccgcactcctgcccagagtggggcctgggaccccaacaaccccaacacgccgtcacgggctgaggaagaatatgagtatgctttcgatgatgagcccaccccgtccccgcaggcctatgggggaacccccaatccccaaacacctggctacccagacccctcgtccccacaggtcaacccacaatacaacccgcagacgccagggacgccggccatgtacaacacagaccagttctctccctatgctgccccctccccacaaggttcctaccagcccagccccagcccccagagctaccaccaggtggcgccaagcccagcaggctaccagaatacccactccccagccagctaccaccctacaccgtcgcccatggcctatcaggctagccccagcccgagccccgttggctacagtcctatgacacctggagctccctcccctggtggctacaacccacacacgccaggctcaggcatcgagcagaactccagcgactgggtaaccactgacattcaggtgaaggtgcgggacacctacctggatacacaggtggtgggacagacaggtgtcatccgcagtgtcacggggggcatgtgctctgtgtacctgaaggacagtgagaaggttgtcagcatttccagtgagcacctggagcctatcacccccaccaagaacaacaaggtgaaagtgatcctgggcgaggatcgggaagccacgggcgtcctactgagcattgatggtgaggatggcattgtccgtatggaccttgatgagcagctcaagatcctcaacctccgcttcctggggaagctcctggaagcctga
Sequence Length
3264
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
120,499 Da
NCBI Official Full Name
Homo sapiens suppressor of Ty 5 homolog (S. cerevisiae), mRNA
NCBI Official Synonym Full Names
SPT5 homolog, DSIF elongation factor subunit
NCBI Official Symbol
SUPT5H
NCBI Official Synonym Symbols
SPT5; SPT5H; Tat-CT1
NCBI Protein Information
transcription elongation factor SPT5
UniProt Protein Name
Transcription elongation factor SPT5
UniProt Gene Name
SUPT5H
UniProt Synonym Gene Names
SPT5; SPT5H; hSPT5; DSIF p160; DSIF large subunit; Tat-CT1 protein
UniProt Entry Name
SPT5H_HUMAN
Uniprot Description
SPT5: a transcription elongation factor. Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Two alternatively spliced human isoforms have been described.
Protein type: RNA-binding; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 19q13
Cellular Component: nucleoplasm; nucleus
Molecular Function: enzyme binding; protein binding; protein heterodimerization activity
Biological Process: mRNA capping; negative regulation of RNA elongation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of macroautophagy; positive regulation of RNA elongation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; response to organic substance; RNA elongation; RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Research Articles on SUPT5H
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Product Notes
The SUPT5H supt5h (Catalog #AAA1271744) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtcggaca gcgaggacag caacttttcc gaggaggagg acagcgagcg cagcagtgac ggcgaggagg ccgaggtaga cgaagagcgg cggagtgcag cgggcagtga gaaagaagaa gagcctgagg acgaagagga ggaggaagag gaggaggaat atgatgagga agaggaagaa gaagatgatg accgaccccc caagaaaccc cgccatggag gcttcattct ggacgaggct gatgttgacg atgagtatga ggacgaggac cagtgggagg atggagcaga ggacattcta gagaaagaag agattgaagc ctccaatatc gataatgttg tcctggatga agatcgttct ggggctcgcc gcctgcaaaa cctctggagg gaccagcgag aagaagaact gggcgagtat tacatgaaga aatacgccaa gtcatctgtg ggagagacgg tgtatggagg atctgatgag ctctcagacg acatcaccca gcagcagctg ctcccaggag tcaaggatcc caatctgtgg actgtcaaat gtaagattgg ggaggaacgg gccacggcca tttccttgat gcgcaagttc attgcctacc agttcacaga cacgcccctg cagatcaagt cagtagtggc accagagcat gtgaagggct acatctacgt ggaggcctac aagcagaccc acgtgaagca ggccattgag ggggtgggca acctgcggct tggctactgg aaccagcaga tggtgcccat caaggagatg acagacgtgc tcaaagtggt gaaggaggtg gccaacctga aaccaaagtc ctgggtccgc ctcaagcggg gcatctacaa ggatgacatt gctcaggtgg actacgtgga gcccagccag aacaccatct ccctgaagat gatcccacgc atcgactacg atcgcatcaa ggcccgcatg agcttgaaag actggtttgc caaaaggaag aagtttaagc ggcctccaca gaggctgttt gatgctgaga agatcaggtc cctggggggt gatgttgcct ctgatggtga cttcctcatc tttgagggga accgttacag ccggaagggc tttctgttca agagcttcgc catgtctgct gtgatcacgg agggtgtgaa gccaacactc tctgagctgg aaaagtttga ggaccagcca gagggcattg acctggaggt ggtgactgag agcacaggga aggagcggga gcacaacttc caacctgggg acaacgtgga ggtctgtgag ggtgagctca tcaacctgca gggcaagatc ctcagcgtgg atggcaacaa gatcaccatc atgcccaagc atgaggacct caaggacatg ttggagttcc cagcccagga acttagaaaa tacttcaaga tgggggacca cgtgaaggtg attgctggcc gattcgaggg cgacacaggc ctcattgtgc gggtggagga gaatttcgtt atcctgttct ctgacctcac catgcatgag ctgaaggtgc tcccccggga cctgcagctc tgctcagaga cagcatcagg tgtggatgtt gggggccagc atgaatgggg cgagctggtg cagctggatc cccagactgt gggtgtcatc gtgcgactag aacgggagac cttccaggtg ctgaacatgt acgggaaggt ggtgactgtc agacatcagg ctgtgacccg gaagaaggac aaccgctttg ctgtggcctt ggactcagag cagaacaaca tccatgtgaa agacatcgtt aaggtcattg atggccccca ctcaggccga gaaggggaga ttcgccatct cttccgaagc ttcgccttcc tacattgcaa gaaactggtg gagaacgggg gcatgtttgt ctgcaagacc cgccacctgg tgctggctgg gggctcaaag ccccgtgatg tgaccaactt caccgtgggt ggctttgcgc ctatgagtcc ccggatcagc agccccatgc accccagtgc tggaggtcag cgtggcggct ttggtagccc aggtggcggc agtggtggca tgagcagggg ccggggccgg agggacaacg aactcatcgg ccagaccgtg cgcatctccc aggggcccta caaaggctac atcggtgtgg tgaaagatgc cacagagtcc acggcccgtg tggagctgca ctccacctgc cagaccatct ctgtggaccg tcagcggctc accacggtgg gctcacggcg cccgggcggc atgacctcga cctatgggag gacgcccatg tatggctccc agacgcccat gtatggctct ggctcccgaa cacccatgta cggctcacag acacccctcc aggatggtag ccgcacccca cactacggct cacagacgcc cctgcatgat ggcagccgca ctcctgccca gagtggggcc tgggacccca acaaccccaa cacgccgtca cgggctgagg aagaatatga gtatgctttc gatgatgagc ccaccccgtc cccgcaggcc tatgggggaa cccccaatcc ccaaacacct ggctacccag acccctcgtc cccacaggtc aacccacaat acaacccgca gacgccaggg acgccggcca tgtacaacac agaccagttc tctccctatg ctgccccctc cccacaaggt tcctaccagc ccagccccag cccccagagc taccaccagg tggcgccaag cccagcaggc taccagaata cccactcccc agccagctac caccctacac cgtcgcccat ggcctatcag gctagcccca gcccgagccc cgttggctac agtcctatga cacctggagc tccctcccct ggtggctaca acccacacac gccaggctca ggcatcgagc agaactccag cgactgggta accactgaca ttcaggtgaa ggtgcgggac acctacctgg atacacaggt ggtgggacag acaggtgtca tccgcagtgt cacggggggc atgtgctctg tgtacctgaa ggacagtgag aaggttgtca gcatttccag tgagcacctg gagcctatca cccccaccaa gaacaacaag gtgaaagtga tcctgggcga ggatcgggaa gccacgggcg tcctactgag cattgatggt gaggatggca ttgtccgtat ggaccttgat gagcagctca agatcctcaa cctccgcttc ctggggaagc tcctggaagc ctga. It is sometimes possible for the material contained within the vial of "SUPT5H, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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