SLC39A8 cdna clone
SLC39A8 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]
Uniprot Description
SLC39A8: Acts as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transporter; Transporter, SLC family; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 4q24
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: zinc ion transmembrane transporter activity
Biological Process: cellular zinc ion homeostasis; zinc ion transport
Disease: Congenital Disorder Of Glycosylation, Type Iin
Research Articles on SLC39A8
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Product Notes
The SLC39A8 slc39a8 (Catalog #AAA1276357) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggccccgg gtcgcgcggt ggccgggctc ctgttgctgg cggccgccgg cctcggagga gtggcggagg ggccagggct agccttcagc gaggatgtgc tgagcgtgtt cggcgcgaat ctgagcctgt cggcggcgca gctccagcac ttgctggagc agatgggagc cgcctcccgc gtgggcgtcc cggagcctgg ccagctgcac ttcaaccagt gtttaactgc tgaagagatc ttttcccttc atggcttttc aaatgctacc caaataacca gctccaaatt ctctgtcatc tgtccagcag tcttacagca attgaacttt cacccatgtg aggatcggcc caagcacaaa acaagaccaa gtcattcaga agtttgggga tatggattcc tgtcagtgac gattattaat ctggcatctc tcctcggatt gattttgact ccactgataa agaaatctta tttcccaaag attttgacct tttttgtggg gctggctatt gggactcttt tttcaaatgc aattttccaa cttattccag aggcatttgg atttgatccc aaagtcgaca gttatgttga gaaggcagtt gctgtgtttg gtggatttta cctacttttc ttttttgaaa gaatgctaaa gatgttatta aagacatatg gtcagaatgg tcatacccac tttggaaatg ataactttgg tcctcaagaa aaaactcatc aacctaaagc attacctgcc atcaatggtg tgacatgcta tgcaaatcct gctgtcacag aagctaatgg acatatccat tttgataatg tcagtgtggt atctctacag gatggaaaaa aagagccaag ttcatgtacc tgtttgaagg ggcccaaact gtcagaaata gggacgattg cctggatgat aacgctctgc gatgccctcc acaatttcat cgatggcctg gcgattgggg cttcctgcac cttgtctctc cttcagggac tcagtacttc catagcaatc ctatgtgagg agtttcccca cgagttagga gactttgtga tcctactcaa tgcagggatg agcactcgac aagccttgct attcaacttc ctttctgcat gttcctgcta tgttgggcta gcttttggca ttttggtggg caacaatttc gctccaaata ttatatttgc acttgctgga ggcatgttcc tctatatttc tctggcagat atgtttccag agatgaatga tatgctgaga gaaaaggtaa ctggaagaaa aaccgatttc accttcttca tgattcagaa tgctggaatg ttaactggat tcacagccat tctactcatt accttgtatg caggagaaat cgaattggag taa. It is sometimes possible for the material contained within the vial of "SLC39A8, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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