SENP5 cdna clone
SENP5 cDNA Clone
Synonyms
SENP5; SENP5 cDNA Clone; SENP5 cdna clone
Sequence
atgaaaaaacagaggaaaattctatggaggaaaggaatccacttagccttttctgagaaatggaatactgggtttggaggctttaagaagttttattttcaccaacacttgtgcattctgaaagctaagctgggaaggccagttacttggaatagacagttgagacatttccagggtagaaagaaagctcttcaaatccagaaaacgtggatcaaggatgaacacctttgtgctaagaccaagttcaatgtggctactcaaaatgttagtactttgtcctctaaagtgaaaagaaaggacgctaaacacttcatttcctcctcaaagactctcctgagactccaagcagagaagctgttgtcatcagcaaagaattctgaccatgaatactgcagagagaaaaatctcttgaaggcagttactgactttccatcaaatagtgctttaggtcaggccaatggtcacagacctaggacagacccacaaccttctgactttcccatgaagttcaatggggagagccaaagtccaggtgagagtggcacgattgtggtcaccttgaacaaccataagagaaagggcttttgttacggctgctgccaagggccggagcaccacaggaatgggggacccttgattccaaaaaagttccaacttaaccaacatagaaggataaaattatctcctcttatgatgtatgagaaattatccatgattagatttcggtacaggattctcagatcccagcacttcagaaccaaaagcaaggtttgcaagctaagaaaagcccagcgaagctgggtacagaaagtcactggggaccatcaagagacccgtagggagaacggtgagggtggcagttgcagcccatttccttccccagaacctaaagacccttcttgtcggcatcagccgtactttccagatatggacagcagtgctgtggtgaaggggacgaactctcatgtgcctgattgccacactaaaggaagctctttcttgggcaaggagcttagtttagacgaagcattccctgaccaacagaatggcagtgccacaaacgcctgggaccagtcatcctgttcttctcctaagtgggagtgtacagagctgattcatgacatccccttaccagaacatcgttctaataccatgttcatttcagaaactgaaagagaaattatgactctgggtcaggaaaatcagacaagttctgtcagtgatgacagagtaaaactgtcagtgtctggagcagatacatctgtgagtagcgtagatgggcctgtgtcccaaaaggctgttcaaaatgagaactcataccagatggaggaggatggatctctcaagcagagcattcttagttctgagttgctggaccacccttactgtaaaagtccactggaggctcccttggtgtgcagtggactcaaactagaaaatcaagtaggaggtggaaagaacagtcagaaagcctctccagtggatgatgaacagctgtcagtctgtctttctggattcctagatgaggttatgaagaagtatggcagtttggttccactcagtgaaaaagaagtccttggaagattaaaagatgtctttaatgaagacttttctaatagaaaaccatttatcaatagggaaataacaaactatcgggccagacatcaaaaatgtaacttccgtatcttctataataaacacatgctggatatggacgacctggcgactctggatggtcagaactggctgaatgaccaggtcattaatatgtatggtgagctgataatggatgcagtcccagacaaagttcacttcttcaacagcttttttcatagacagctggtaaccaaaggatataatggagtaaaaagatggactaaaaaggtggatttgtttaaaaagagtcttctgttgattcctattcacctggaagtccactggtctctcattactgtgacactctctaatcgaattatttcattttatgattcccaaggcattcattttaagttttgtgtagagaatataagaaagtatttgctgactgaagccagagaaaaaaatagacctgaatttcttcagggttggcagactgctgttacgaagtgtattccacaacagaaaaacgacagtgactgtggagtctttgtgctccagtactgcaagtgcctcgccttagagcagcctttccagttttcacaagaagacatgccccgagtgcggaagaggatttacaaggagctatgtgagtgccggctcatggactga
Sequence Length
2268
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
81,310 Da
NCBI Official Full Name
Homo sapiens SUMO1/sentrin specific peptidase 5, mRNA
NCBI Official Synonym Full Names
SUMO1/sentrin specific peptidase 5
NCBI Official Symbol
SENP5
NCBI Protein Information
sentrin-specific protease 5
UniProt Protein Name
Sentrin-specific protease 5
Protein Family
UniProt Gene Name
SENP5
UniProt Entry Name
SENP5_HUMAN
NCBI Description
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]
Uniprot Description
SENP5: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. Belongs to the peptidase C48 family.
Protein type: EC 3.4.22.68; Nucleolus; Protease
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus
Molecular Function: endopeptidase activity; protein binding; SUMO-specific protease activity
Biological Process: protein desumoylation; protein sumoylation
Research Articles on SENP5
Similar Products
Product Notes
The SENP5 senp5 (Catalog #AAA1274156) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaaaaaac agaggaaaat tctatggagg aaaggaatcc acttagcctt ttctgagaaa tggaatactg ggtttggagg ctttaagaag ttttattttc accaacactt gtgcattctg aaagctaagc tgggaaggcc agttacttgg aatagacagt tgagacattt ccagggtaga aagaaagctc ttcaaatcca gaaaacgtgg atcaaggatg aacacctttg tgctaagacc aagttcaatg tggctactca aaatgttagt actttgtcct ctaaagtgaa aagaaaggac gctaaacact tcatttcctc ctcaaagact ctcctgagac tccaagcaga gaagctgttg tcatcagcaa agaattctga ccatgaatac tgcagagaga aaaatctctt gaaggcagtt actgactttc catcaaatag tgctttaggt caggccaatg gtcacagacc taggacagac ccacaacctt ctgactttcc catgaagttc aatggggaga gccaaagtcc aggtgagagt ggcacgattg tggtcacctt gaacaaccat aagagaaagg gcttttgtta cggctgctgc caagggccgg agcaccacag gaatggggga cccttgattc caaaaaagtt ccaacttaac caacatagaa ggataaaatt atctcctctt atgatgtatg agaaattatc catgattaga tttcggtaca ggattctcag atcccagcac ttcagaacca aaagcaaggt ttgcaagcta agaaaagccc agcgaagctg ggtacagaaa gtcactgggg accatcaaga gacccgtagg gagaacggtg agggtggcag ttgcagccca tttccttccc cagaacctaa agacccttct tgtcggcatc agccgtactt tccagatatg gacagcagtg ctgtggtgaa ggggacgaac tctcatgtgc ctgattgcca cactaaagga agctctttct tgggcaagga gcttagttta gacgaagcat tccctgacca acagaatggc agtgccacaa acgcctggga ccagtcatcc tgttcttctc ctaagtggga gtgtacagag ctgattcatg acatcccctt accagaacat cgttctaata ccatgttcat ttcagaaact gaaagagaaa ttatgactct gggtcaggaa aatcagacaa gttctgtcag tgatgacaga gtaaaactgt cagtgtctgg agcagataca tctgtgagta gcgtagatgg gcctgtgtcc caaaaggctg ttcaaaatga gaactcatac cagatggagg aggatggatc tctcaagcag agcattctta gttctgagtt gctggaccac ccttactgta aaagtccact ggaggctccc ttggtgtgca gtggactcaa actagaaaat caagtaggag gtggaaagaa cagtcagaaa gcctctccag tggatgatga acagctgtca gtctgtcttt ctggattcct agatgaggtt atgaagaagt atggcagttt ggttccactc agtgaaaaag aagtccttgg aagattaaaa gatgtcttta atgaagactt ttctaataga aaaccattta tcaataggga aataacaaac tatcgggcca gacatcaaaa atgtaacttc cgtatcttct ataataaaca catgctggat atggacgacc tggcgactct ggatggtcag aactggctga atgaccaggt cattaatatg tatggtgagc tgataatgga tgcagtccca gacaaagttc acttcttcaa cagctttttt catagacagc tggtaaccaa aggatataat ggagtaaaaa gatggactaa aaaggtggat ttgtttaaaa agagtcttct gttgattcct attcacctgg aagtccactg gtctctcatt actgtgacac tctctaatcg aattatttca ttttatgatt cccaaggcat tcattttaag ttttgtgtag agaatataag aaagtatttg ctgactgaag ccagagaaaa aaatagacct gaatttcttc agggttggca gactgctgtt acgaagtgta ttccacaaca gaaaaacgac agtgactgtg gagtctttgt gctccagtac tgcaagtgcc tcgccttaga gcagcctttc cagttttcac aagaagacat gccccgagtg cggaagagga tttacaagga gctatgtgag tgccggctca tggactga. It is sometimes possible for the material contained within the vial of "SENP5, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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