RBM15 cdna clone
RBM15 cDNA Clone
Gene Names
RBM15; OTT; OTT1; SPEN
Synonyms
RBM15; RBM15 cDNA Clone; RBM15 cdna clone
Sequence
ATGAGGACTGCGGGGCGGGACCCTGTGCCGCGGCGGAGTCCAAGATGGCGGCGTGCGGTTCCGCTGTGTGAAACGAGCGCGGGGCGGCGGGTTACTCAGCTCCGCGGAGACGACCTCCGACGACCCGCAACAATGAAGGGAAAAGAGCGCTCGCCAGTGAAGGCCAAACGCTCCCGTGGTGGTGAGGACTCGACTTCCCGCGGTGAGCGGAGCAAGAAGTTAGGGGGCTCTGGTGGCAGCAATGGGAGCAGCAGCGGAAAGACCGATAGCGGCGGTGGGTCGCGGCGGAGTCTCCACCTGGACAAGTCCAGCAGTCGAGGTGGCAGCCGCGAGTATGATACCGGTGGGGGCAGCTCCAGTAGCCGCTTGCATAGTTATAGCTCCCCGAGCACCAAAAATTCTTCGGGCGGGGGCGAGTCGCGCAGCAGCTCCCGGGGTGGAGGCGGGGAGTCACGTTCCTCTGGGGCCGCCTCCTCAGCTCCCGGCGGCGGGGACGGCGCGGAATACAAGACTCTGAAGATAAGCGAGTTGGGGTCCCAGCTTAGTGACGAAGCGGTGGAGGACGGCCTGTTTCATGAGTTCAAACGCTTCGGTGATGTAAGTGTGAAAATCAGTCATCTGTCGGGTTCTGGCAGCGGGGATGAGCGGGTAGCCTTTGTGAACTTCCGGCGGCCAGAGAACGCGCGGGCGGCCAAGCATGCCAGAGGCCGCCTGGTGCTCTATGACCGGCCTCTGAAGATAGAAGCTGTGTATGTGAGCCGGCGCCGCAGCCGCTCCCCTTTAGACAAAGATACTTATCCTCCATCAGCCAGTGTGGTCGGGGCCTCTGTAGGTGGTCACCGGCACCCCCCTGGAGGTGGTGGAGGCCAGAGATCACTTTCCCCTGGTGGCGCTGCTTTGGGATACAGAGACTACCGGCTGCAGCAGTTGGCTCTTGGCCGCCTGCCCCCTCCACCTCCGCCACCATTGCCTCGAGACCTGGAGAGAGAAAGAGACTACCCGTTCTATGAGAGAGTGCGCCCTGCATACAGTCTTGAGCCAAGGGTGGGAGCTGGAGCAGGTGCTGCTCCTTTCAGAGAAGTGGATGAGATTTCACCCGAGGATGATCAGCGAGCTAACCGGACGCTCTTCTTGGGCAACCTAGACATCACTGTAACGGAGAGTGATTTAAGAAGGGCGTTTGATCGCTTTGGAGTCATCACAGAAGTAGATATCAAGAGGCCTTCTCGCGGCCAGACTAGTACTTACGGCTTTCTCAAATTTGAGAACTTAGATATGTCTCACCGGGCCAAATTAGCAATGTCTGGCAAAATTATAATTCGGAATCCTATCAAAATTGGTTATGGTAAAGCTACACCCACCACCCGCCTCTGGGTGGGAGGCCTGGGACCTTGGGTTCCTCTTGCTGCCCTGGCACGAGAATTTGATCGATTTGGCACCATACGCACCATAGACTACCGAAAAGGTGATAGTTGGGCATATATCCAGTATGAAAGCCTGGATGCAGCGCATGCTGCCTGGACCCATATGCGGGGCTTCCCTCTTGGTGGCCCAGATCGACGCCTTAGAGTAGACTTTGCCGACACCGAACATCGTTACCAGCAGCAGTATCTGCAGCCTCTGCCCTTGACTCATTATGAGCTGGTGACAGATGCTTTTGGACATCGGGCACCAGACCCTTTGAGGGGTGCTCGGGATAGGACACCACCCTTACTATACAGAGATCGTGATAGGGACCTTTATCCTGACTCTGATTGGGTGCCACCCCCACCCCCAGTCCGAGAACGCAGCACTCGGACTGCAGCTACTTCTGTGCCTGCTTACGAGCCACTGGATAGCCTAGATCGCAGGCGGGATGGTTGGTCCTTGGACCGGGACAGAGGTGATCGAGATCTGCCCAGCAGCAGAGACCAGCCTAGGAAGCGAAGGCTGCCTGAGGAGAGTGGAGGACGTCATCTGGATAGGTCTCCTGAGAGTGACCGCCCACGAAAACGTCACTGCGCTCCTTCTCCTGACCGCAGTCCAGAATTGAGCAGTAGCCGGGATCGTTACAACAGCGACAATGATCGATCTTCCCGTCTTCTCTTGGAAAGGCCCTCTCCAATCAGAGACAGACGAGGTAGTTTGGAGAAGAGCCAGGGTGACAAGCGAGACCGTAAAAACTCTGCATCAGCTGAACGAGATAGGAAGCACCGGACAACTGCTCCCACTGAGGGAAAAAGCCCTCTGAAAAAAGAAGACCGCTCTGATGGGAGTGCACCTAGCACCAGCACTGCTTCCTCCAAGCTGAAGTCCCCGTCCCAGAAACAGGATGGGGGGACAGCCCCTGTGGCATCAGCCTCTCCCAAACTCTGTTTGGCCTGGCAGGGCATGCTTCTACTGAAGAACAGCAACTTTCCTTCCAACATGCATCTGTTGCAGGGTGACCTCCAAGTGGCTAGTAGTCTTCTTGTGGAGGGTTCAACTGGAGGCAAAGTGGCCCAGCTCAAGATCACTCAGCGTCTCCGTTTGGACCAGCCCAAGTTGGATGAAGTAACTCGACGCATCAAAGTAGCAGGGCCCAATGGTTATGCCATTCTTTTGGCTGTGCCTGGAAGTTCTGACAGCCGGTCCTCCTCTTCCTCAGCTGCATCAGACACTGCCACTTCTACTCAGAGGCCACTTAGGAACCTTGTGTCCTATTTAAAGCAAAAGCAGGCAGCCGGGGTGATCAGCCTCCCTGTGGGGGGCAACAAAGACAAGGAAAACACCGGGGTCCTTCATGCCTTCCCACCTTGTGAGTTCTCCCAGCAGTTCCTGGATTCCCCTGCCAAGGCACTGGCCAAATCTGAAGAAGATTACCTGGTCATGATCATTGTCCGTGCAAAACTGGTTGAACAGCGGATGAAGATATGGAATTCAAAGCTCTAA
Sequence Length
2910
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
99,701 Da
NCBI Official Full Name
Homo sapiens RNA binding motif protein 15, mRNA
NCBI Official Synonym Full Names
RNA binding motif protein 15
NCBI Official Symbol
RBM15
NCBI Official Synonym Symbols
OTT; OTT1; SPEN
NCBI Protein Information
putative RNA-binding protein 15
UniProt Protein Name
Putative RNA-binding protein 15
Protein Family
UniProt Gene Name
RBM15
UniProt Synonym Gene Names
OTT; OTT1
UniProt Entry Name
RBM15_HUMAN
NCBI Description
Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]
Uniprot Description
RBM15: May be implicated in HOX gene regulation. A chromosomal aberration involving RBM15 may be a cause of acute megakaryoblastic leukemia. Translocation t(1;22)(p13;q13) with MKL1. Although both reciprocal fusion transcripts are detected in acute megakaryoblastic leukemia (AMKL, FAB-M7), the RBM15-MKL1 chimeric protein has all the putative functional domains encoded by each gene and is the candidate oncogene. Belongs to the RRM Spen family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Spliceosome; RNA-binding; Oncoprotein
Chromosomal Location of Human Ortholog: 1p13
Cellular Component: nuclear speck; nucleoplasm
Molecular Function: nucleic acid binding; protein binding
Biological Process: negative regulation of transcription, DNA-dependent; nuclear mRNA splicing, via spliceosome
Research Articles on RBM15
Similar Products
Product Notes
The RBM15 rbm15 (Catalog #AAA1272346) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGAGGACTG CGGGGCGGGA CCCTGTGCCG CGGCGGAGTC CAAGATGGCG GCGTGCGGTT CCGCTGTGTG AAACGAGCGC GGGGCGGCGG GTTACTCAGC TCCGCGGAGA CGACCTCCGA CGACCCGCAA CAATGAAGGG AAAAGAGCGC TCGCCAGTGA AGGCCAAACG CTCCCGTGGT GGTGAGGACT CGACTTCCCG CGGTGAGCGG AGCAAGAAGT TAGGGGGCTC TGGTGGCAGC AATGGGAGCA GCAGCGGAAA GACCGATAGC GGCGGTGGGT CGCGGCGGAG TCTCCACCTG GACAAGTCCA GCAGTCGAGG TGGCAGCCGC GAGTATGATA CCGGTGGGGG CAGCTCCAGT AGCCGCTTGC ATAGTTATAG CTCCCCGAGC ACCAAAAATT CTTCGGGCGG GGGCGAGTCG CGCAGCAGCT CCCGGGGTGG AGGCGGGGAG TCACGTTCCT CTGGGGCCGC CTCCTCAGCT CCCGGCGGCG GGGACGGCGC GGAATACAAG ACTCTGAAGA TAAGCGAGTT GGGGTCCCAG CTTAGTGACG AAGCGGTGGA GGACGGCCTG TTTCATGAGT TCAAACGCTT CGGTGATGTA AGTGTGAAAA TCAGTCATCT GTCGGGTTCT GGCAGCGGGG ATGAGCGGGT AGCCTTTGTG AACTTCCGGC GGCCAGAGAA CGCGCGGGCG GCCAAGCATG CCAGAGGCCG CCTGGTGCTC TATGACCGGC CTCTGAAGAT AGAAGCTGTG TATGTGAGCC GGCGCCGCAG CCGCTCCCCT TTAGACAAAG ATACTTATCC TCCATCAGCC AGTGTGGTCG GGGCCTCTGT AGGTGGTCAC CGGCACCCCC CTGGAGGTGG TGGAGGCCAG AGATCACTTT CCCCTGGTGG CGCTGCTTTG GGATACAGAG ACTACCGGCT GCAGCAGTTG GCTCTTGGCC GCCTGCCCCC TCCACCTCCG CCACCATTGC CTCGAGACCT GGAGAGAGAA AGAGACTACC CGTTCTATGA GAGAGTGCGC CCTGCATACA GTCTTGAGCC AAGGGTGGGA GCTGGAGCAG GTGCTGCTCC TTTCAGAGAA GTGGATGAGA TTTCACCCGA GGATGATCAG CGAGCTAACC GGACGCTCTT CTTGGGCAAC CTAGACATCA CTGTAACGGA GAGTGATTTA AGAAGGGCGT TTGATCGCTT TGGAGTCATC ACAGAAGTAG ATATCAAGAG GCCTTCTCGC GGCCAGACTA GTACTTACGG CTTTCTCAAA TTTGAGAACT TAGATATGTC TCACCGGGCC AAATTAGCAA TGTCTGGCAA AATTATAATT CGGAATCCTA TCAAAATTGG TTATGGTAAA GCTACACCCA CCACCCGCCT CTGGGTGGGA GGCCTGGGAC CTTGGGTTCC TCTTGCTGCC CTGGCACGAG AATTTGATCG ATTTGGCACC ATACGCACCA TAGACTACCG AAAAGGTGAT AGTTGGGCAT ATATCCAGTA TGAAAGCCTG GATGCAGCGC ATGCTGCCTG GACCCATATG CGGGGCTTCC CTCTTGGTGG CCCAGATCGA CGCCTTAGAG TAGACTTTGC CGACACCGAA CATCGTTACC AGCAGCAGTA TCTGCAGCCT CTGCCCTTGA CTCATTATGA GCTGGTGACA GATGCTTTTG GACATCGGGC ACCAGACCCT TTGAGGGGTG CTCGGGATAG GACACCACCC TTACTATACA GAGATCGTGA TAGGGACCTT TATCCTGACT CTGATTGGGT GCCACCCCCA CCCCCAGTCC GAGAACGCAG CACTCGGACT GCAGCTACTT CTGTGCCTGC TTACGAGCCA CTGGATAGCC TAGATCGCAG GCGGGATGGT TGGTCCTTGG ACCGGGACAG AGGTGATCGA GATCTGCCCA GCAGCAGAGA CCAGCCTAGG AAGCGAAGGC TGCCTGAGGA GAGTGGAGGA CGTCATCTGG ATAGGTCTCC TGAGAGTGAC CGCCCACGAA AACGTCACTG CGCTCCTTCT CCTGACCGCA GTCCAGAATT GAGCAGTAGC CGGGATCGTT ACAACAGCGA CAATGATCGA TCTTCCCGTC TTCTCTTGGA AAGGCCCTCT CCAATCAGAG ACAGACGAGG TAGTTTGGAG AAGAGCCAGG GTGACAAGCG AGACCGTAAA AACTCTGCAT CAGCTGAACG AGATAGGAAG CACCGGACAA CTGCTCCCAC TGAGGGAAAA AGCCCTCTGA AAAAAGAAGA CCGCTCTGAT GGGAGTGCAC CTAGCACCAG CACTGCTTCC TCCAAGCTGA AGTCCCCGTC CCAGAAACAG GATGGGGGGA CAGCCCCTGT GGCATCAGCC TCTCCCAAAC TCTGTTTGGC CTGGCAGGGC ATGCTTCTAC TGAAGAACAG CAACTTTCCT TCCAACATGC ATCTGTTGCA GGGTGACCTC CAAGTGGCTA GTAGTCTTCT TGTGGAGGGT TCAACTGGAG GCAAAGTGGC CCAGCTCAAG ATCACTCAGC GTCTCCGTTT GGACCAGCCC AAGTTGGATG AAGTAACTCG ACGCATCAAA GTAGCAGGGC CCAATGGTTA TGCCATTCTT TTGGCTGTGC CTGGAAGTTC TGACAGCCGG TCCTCCTCTT CCTCAGCTGC ATCAGACACT GCCACTTCTA CTCAGAGGCC ACTTAGGAAC CTTGTGTCCT ATTTAAAGCA AAAGCAGGCA GCCGGGGTGA TCAGCCTCCC TGTGGGGGGC AACAAAGACA AGGAAAACAC CGGGGTCCTT CATGCCTTCC CACCTTGTGA GTTCTCCCAG CAGTTCCTGG ATTCCCCTGC CAAGGCACTG GCCAAATCTG AAGAAGATTA CCTGGTCATG ATCATTGTCC GTGCAAAACT GGTTGAACAG CGGATGAAGA TATGGAATTC AAAGCTCTAA. It is sometimes possible for the material contained within the vial of "RBM15, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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