RAB5C cdna clone

RAB5C

Cat. Num. AAA200960

• Gene Names: RAB5C; RABL; L1880; RAB5L; RAB5CL
• Synonyms: RAB5C; L1880; RAB5CL; RAB5L; RABL; RAB5C cdna clone

• Form/Format: Lyophilized
• Sequence: Nucleotide Sequence: ATGGCGGGTCGGGGAGGCGCAGCACGACCCAATGGACCAGCTGCTGGGAACAAGATCTGTCAATTTAAGCTGGTTCTGCTGGGGGAGTCTGCGGTAGGCAAATCCAGCCTCGTCCTCCGCTTTGTCAAGGGACAGTTTCACGAGTACCAGGAGAGCACAATTGGAGCGGCCTTCCTCACACAGACTGTCTGCCTGGATGACACAACAGTCAAGTTTGAGATCTGGGACACAGCTGGACAGGAGCGGTATCACAGCCTGGCCCCCATGTACTATCGGGGGGCCCAGGCTGCCATCGTGGTCTATGACATCACCAACACAGATACATTTGCACGGGCCAAGAACTGGGTGAAGGAGCTACAGAGGCAGGCCAGCCCCAACATCGTCATTGCACTCGCGGGTAACAAGGCAGACCTGGCCAGCAAGAGAGCCGTGGAATTCCAGGAAGCACAAGCCTATGCAGACGACAACAGTTTGCTGTTCATGGAGACATCAGCAAAGACTGCAATGAACGTGAACGAAATCTTCATGGCAATAGCTAAGAAGCTTCCCAAGAACGAGCCCCAGAATGCAACTGGTGCTCCAGGCCGAAACCGAGGTGTGGACCTCCAGGAGAACAACCCAGCCAGCCGGAGCCAGTGCTGCAGCAACTGA; ; Translation Sequence: MAGRGGAARP NGPAAGNKIC QFKLVLLGES AVGKSSLVLR FVKGQFHEYQ ESTIGAAFLTQTVCLDDTTV KFEIWDTAGQ ERYHSLAPMY YRGAQAAIVV YDITNTDTFA RAKNWVKELQRQASPNIVIA LAGNKADLAS KRAVEFQEAQ AYADDNSLLF METSAKTAMN VNEIFMAIAKKLPKNEPQNA TGAPGRNRGV DLQENNPASR SQCCSN
• Sequence Length: 216

• Species: Human
• Chromosome Location: 17q21.2
• OMIM Reference Number: 604037
• cDNA Size: 651bp
• Vector Description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
• Vector: (puc19-derived cloning vector)
• Preparation Before Usage: 1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
• Preparation and Storage: Store the plasmid at -20 degree C.

Related Product Information for RAB5C cdna clone

RAB5C belongs to the small GTPase superfamily of the ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment.

Product Categories/Family for RAB5C cdna clone

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 41393545
• NCBI GeneID: 5878
• NCBI Accession #: NP_004574.2
• NCBI GenBank Nucleotide #: NM_004583.3
• UniProt Accession #: P51148
• NCBI Official Full Name: ras-related protein Rab-5C isoform a
• NCBI Official Synonym Full Names: RAB5C, member RAS oncogene family
• NCBI Official Symbol: RAB5C
• NCBI Official Synonym Symbols: RABL; L1880; RAB5L; RAB5CL
• NCBI Protein Information: ras-related protein Rab-5C
• UniProt Protein Name: Ras-related protein Rab-5C
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB5C
• UniProt Synonym Gene Names: RABL
• UniProt Entry Name: RAB5C_HUMAN

NCBI Description

Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010]

Uniprot Description

RAB5C: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric, Rab; Motility/polarity/chemotaxis; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: intracellular membrane-bound organelle; lysosomal membrane; endocytic vesicle; early endosome membrane; early endosome; plasma membrane; melanosome; lipid particle

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding

Biological Process: intracellular protein transport; metabolic process; regulation of endocytosis; plasma membrane to endosome transport; Rab protein signal transduction