POU4F3 cdna clone
POU4F3 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15. [provided by RefSeq, Mar 2009]
Uniprot Description
POU4F3: May play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in POU4F3 are the cause of deafness autosomal dominant type 15 (DFNA15). DFNA15 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Belongs to the POU transcription factor family. Class- 4 subfamily.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 5q32
Cellular Component: nucleoplasm
Molecular Function: transcription factor activity
Biological Process: positive regulation of transcription from RNA polymerase II promoter; visual perception
Disease: Deafness, Autosomal Dominant 15
Research Articles on POU4F3
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Product Notes
The POU4F3 pou4f3 (Catalog #AAA1273721) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGATGGCCA TGAACTCCAA GCAGCCTTTC GGCATGCACC CGGTGCTGCA AGAACCCAAA TTCTCCAGTC TGCACTCTGG CTCCGAGGCT ATGCGCCGAG TCTGTCTCCC AGCCCCGCAG CTGCAGGGTA ATATATTTGG AAGCTTTGAT GAGAGCCTGC TGGCACGCGC CGAAGCTCTG GCGGCGGTGG ATATCGTCTC CCACGGCAAG AACCATCCGT TCAAGCCCGA CGCCACCTAC CATACCATGA GCAGCGTGCC CTGCACGTCC ACTTCGTCCA CCGTGCCCAT CTCCCACCCA GCTGCGCTCA CCTCACACCC TCACCACGCC GTGCACCAGG GCCTCGAAGG CGACCTGCTG GAGCACATCT CGCCCACGCT GAGTGTGAGC GGCCTGGGCG CTCCGGAACA CTCGGTGATG CCCGCACAGA TCCATCCACA CCACCTGGGC GCCATGGGCC ACCTGCACCA GGCCATGGGC ATGAGTCACC CGCACACCGT GGCCCCTCAT AGCGCCATGC CTGCATGCCT CAGCGACGTG GAGTCAGACC CGCGCGAGCT GGAAGCCTTC GCCGAGCGCT TCAAGCAGCG GCGCATCAAG CTGGGGGTGA CCCAGGCGGA CGTGGGCGCG GCTCTGGCTA ATCTCAAGAT CCCCGGCGTG GGCTCGCTGA GCCAAAGCAC CATCTGCAGG TTCGAGTCTC TCACTCTCTC GCACAACAAC ATGATCGCTC TCAAGCCGGT GCTCCAGGCC TGGTTGGAGG AGGCCGAGGC CGCCTACCGA GAGAAGAACA GCAAGCCAGA GCTCTTCAAC GGCAGCGAAC GGAAGCGCAA ACGCACGTCC ATCGCGGCGC CGGAGAAGCG TTCACTCGAG GCCTATTTCG CTATCCAGCC ACGTCCTTCA TCTGAGAAGA TCGCGGCCAT CGCTGAGAAA CTGGACCTTA AAAAGAACGT GGTGAGAGTC TGGTTCTGCA ACCAGAGACA GAAACAGAAA CGAATGAAGT ATTCGGCTGT CCACTGA. It is sometimes possible for the material contained within the vial of "POU4F3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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