P2RX6 cdna clone
P2RX6 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]
Uniprot Description
P2X6: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
Protein type: Membrane protein, integral; Channel, cation; Channel, ligand-gated; Membrane protein, multi-pass; Receptor, misc.
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component: cell junction; cytoplasm; integral to nuclear inner membrane; plasma membrane
Molecular Function: ATP-gated cation channel activity; channel activity; identical protein binding; purinergic nucleotide receptor activity; transmembrane receptor activity
Biological Process: blood coagulation; muscle contraction; protein homooligomerization; signal transduction; transport
Research Articles on P2RX6
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Product Notes
The P2RX6 p2rx6 (Catalog #AAA1267930) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGGCTCCC CAGGGGCTAC GACAGGCTGG GGGCTTCTGG ATTATAAGAC GGAGAAGTGG GCTCTCCTCG CCAAAAAAGG CTACCAGGAG CGGGACCTGG AACCCCAGTT TTCCATCATC ACCAAACTCA AAGGGGTTTC CGTCACTCAG ATCAAGGAGC TTGGAAACCG GCTGTGGGAT GTGGCCGACT TCGTGAAGCC ACCTCAGGGA GAGAACGTGT TCTTCTTGGT GACCAACTTC CTTGTGACGC CAGCCCAAGT TCAGGGCAGA TGCCCAGAGC ACCCGTCCGT CCCACTGGCT AACTGCTGGG TCGACGAGGA CTGCCCCGAA GGGGAGGGAG GCACACACAG CCACGGTGTA AAAACAGGCC AGTGTGTGGT GTTCAATGGG ACCCACAGGA CCTGTGAGAT CTGGAGTTGG TGCCCAGTGG AGAGTGGCGT TGTGCCCTCG AGGCCCCTGC TGGCCCAGGC CCAGAACTTC ACACTGTTCA TCAAAAACAC AGTCACCTTC AGCAAGTTCA ACTTCTCTAA GTCCAATGCC TTGGAGACCT GGGACCCCAC CTATTTTAAG CACTGCCGCT ATGAACCACA ATTCAGCCCC TACTGTCCCG TGTTCCACAT TGGGGACCTC GTGGCCAAGG CTGGAGGGAC CTTCGAGGAC CTGGCGTTGC TGGGTGGCTC TGTAGGCATC AGAGTTCACT GGGATTGTGA CCTGGACACC GGGGACTCTG GCTGCTGGCC TCACTACTCC TTCCAGCTGC AGGAGAAGAG CTACAACTTC AGGACAGCCA CTCACTGGTG GGAGCAACCG GGTGTGGAGG CCCGCACCCT GCTCAAGCTC TATGGAATCC GCTTCGACAT CCTCGTCACC GGGCAGGCAG GGAAGTTCGG GCTCATCCCC ACGGCCGTCA CACTGGGCAC CGGGGCAGCT TGGCTGGGCG TGGTCACCTT TTTCTGTGAC CTGCTACTGC TGTATGTGGA TAGAGAAGCC CATTTCTACT GGAGGACAAA GTATGAGGAG GCCAAGGCCC CGAAAGCAAC CGCCAACTCT GTGTGGAGGG AGCTGGCCCT TGCATCCCAA GCCCGACTGG CCGAGTGCCT CAGACGGAGC TCAGCACCTG CACCCACGGC CACTGCTGCT GGGAGTCAGA CACAGACACC AGGATGGCCC TGTCCAAGTT CTGACACCCA CTTGCCAACC CATTCCGGGA GCCTGTAG. It is sometimes possible for the material contained within the vial of "P2RX6, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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