OXA1L cdna clone
OXA1L cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an evolutionarily conserved protein that is localized to the inner mitochondrial membrane. The encoded protein is essential for the translocation of the N-terminal tail of subunit 2 of cytochrome c oxidase, and is involved in the assembly of the cytochrome c oxidase and ATPase complexes of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2016]
Uniprot Description
OXA1L: Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria. Belongs to the OXA1/ALB3/YidC family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Mitochondrial
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: mitochondrial membrane; mitochondrion; protein complex
Molecular Function: protein binding; protein homodimerization activity
Biological Process: aerobic respiration; mitochondrial proton-transporting ATP synthase complex assembly; mitochondrial respiratory chain complex I assembly; negative regulation of ATPase activity; negative regulation of oxidoreductase activity; protein tetramerization
Research Articles on OXA1L
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Product Notes
The OXA1L oxa1l (Catalog #AAA1266470) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGTAACGT GGCTTTACAG ATTTTTACCC ACTTCAAATA TGGCCGCCAA GCTCCGTTCT CTTTTACCGC CTGATCTACG GCTACAATTC TGGCTTCATG CCCGCCTCCA AAAGTGCTTC CTCTCGAGGG GTTGTGGTTC TTACTGCGCA GGCGCAAAAG CAAGTCCTCT TCCGGGCAAA ATGGCGATGG GACTAATGTG CGGACGCCGG GAGCTTCTGC GCTTGCTACA GTCCGGGCGT CGGGTCCACA GCGTCGCAGG GCCCTCGCAA TGGCTTGGGA AACCGCTGAC CACACGGCTC CTATTCCCAG TAGCCCCGTG CTGCTGTCGC CCACACTACC TCTTCCTTGC GGCTTCCGGC CCCCGCAGCC TCAGTACCTC TGCTATCTCT TTTGCAGAAG TCCAGGTTCA GGCCCCTCCT GTTGTTGCTG CAACTCCCTC ACCCACAGCA GTACCTGAGG TGGCTTCTGG AGAGACTGCA GATGTAGTCC AAACTGCTGC AGAGCAGAGC TTCGCTGAAC TGGGGCTGGG GTCATACACC CCAGTGGGAC TGATCCAGAA TTTACTGGAA TTTATGCATG TTGATCTGGG CCTACCTTGG TGGGGGGCCA TTGCTGCATG TACAGTCTTT GCCCGCTGCC TGATTTTTCC TCTCATCGTG ACGGGCCAGC GAGAGGCAGC CAGGATCCAC AATCACTTGC CAGAGATCCA GAAGTTTTCC AGTCGAATCA GAGAGGCCAA GTTAGCAGGA GACCATATTG AGTATTACAA GGCTTCCTCG GAGATGGCAC TTTACCAGAA AAAACATGGT ATTAAACTCT ATAAACCTCT CATTCTCCCT GTGACTCAGG CCCCAATCTT CATCTCCTTC TTCATTGCTT TGAGAGAGAT GGCCAACCTT CCTGTGCCCA GCCTGCAGAC AGGTGGCCTC TGGTGGTTCC AGGATCTCAC GGTATCCGAT CCCATCTACA TATTACCACT GGCAGTCACT GCTACAATGT GGGCTGTTCT TGAGCTAGGT GCTGAGACAG GTGTGCAAAG TTCTGACCTT CAGTGGATGA GAAATGTCAT CAGAATGATG CCCCTGATAA CCTTGCCCAT AACCATGCAT TTCCCCACGG CAGTGTTTAT GTACTGGCTC TCCTCCAATT TGTTTTCCCT GGTCCAAGTA TCCTGTCTCC GGATTCCAGC AGTACGCACT GTACTTAAAA TCCCCCAGCG AGTTGTACAT GACCTGGACA AATTACCTCC ACGGGAAGGC TTCCTAGAGA GCTTCAAAAA AGGCTGGAAA AATGCTGAAA TGACGCGTCA GCTGCGAGAG CGTGAACAAC GCATGCGGAA TCAGTTGGAG CTAGCAGCCA GGGGTCCTTT ACGACAGACC TTTACCCACA ACCCTCTCCT ACAACCTGGA AAGGATAACC CTCCCAATAT CCCTAGCAGC AGCAGCAGCA AACCAAAGTC AAAGTATCCC TGGCACGACA CACTTGGCTG A. It is sometimes possible for the material contained within the vial of "OXA1L, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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