Rabbit anti-Human, Mouse OXA1L Polyclonal Antibody | anti-OXA1L antibody

OXA1L antibody

Cat. Num. AAA9412471

• Gene Names: OXA1L; OXA1
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunofluorescence
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: OXA1L; Polyclonal Antibody; OXA1L antibody; OXA1; anti-OXA1L antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total OXA1L antibody.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 495

• Applicable Applications for anti-OXA1L antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500 - 1:2000; Immunofluorescence: 1:50 - 1:200
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human OXA1L.
• Target Name: OXA1L
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using OXA1L antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of U2OS cell using OXA1L antibody. Blue: DAPI for nuclear staining.)

Related Product Information for anti-OXA1L antibody

Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria.

Product Categories/Family for anti-OXA1L antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 223718097
• NCBI GeneID: 5018
• NCBI Accession #: NP_005006.3
• NCBI GenBank Nucleotide #: NM_005015.3
• UniProt Accession #: Q15070; B4DPA2
• Molecular Weight: 28,803 Da
• NCBI Official Full Name: mitochondrial inner membrane protein OXA1L
• NCBI Official Synonym Full Names: oxidase (cytochrome c) assembly 1-like
• NCBI Official Symbol: OXA1L
• NCBI Official Synonym Symbols: OXA1
• NCBI Protein Information: mitochondrial inner membrane protein OXA1L
• UniProt Protein Name: Mitochondrial inner membrane protein OXA1L
• Protein Family: Mitochondrial inner membrane protein
• UniProt Gene Name: OXA1L
• UniProt Synonym Gene Names: OXA1-like protein
• UniProt Entry Name: OXA1L_HUMAN

Uniprot Description

OXA1L: Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria. Belongs to the OXA1/ALB3/YidC family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: protein complex; mitochondrion; mitochondrial membrane; mitochondrial respiratory chain

Molecular Function: protein binding; protein homodimerization activity

Biological Process: mitochondrial respiratory chain complex I assembly; mitochondrial proton-transporting ATP synthase complex assembly; negative regulation of oxidoreductase activity; aerobic respiration; protein complex assembly; protein insertion into membrane; negative regulation of ATPase activity; protein tetramerization