KRT86 cdna clone
KRT86 cDNA Clone
Gene Names
KRT86; HB6; Hb1; K86; MNX; KRTHB1; KRTHB6
Synonyms
KRT86; KRT86 cDNA Clone; KRT86 cdna clone
Sequence
atgacttgtggatcttactgtggtggccgcgccttcagctgcatctcggcctgcgggccccggcccggccgctgctgcatcaccgccgccccctaccgtggcatctcctgctaccgcggcctcaccgggggcttcggcagccacagcgtgtgcggaggctttcgggccggctcctgcggacgcagcttcggctaccgctccgggggcgtgtgcgggcccagtcccccatgcatcaccaccgtgtcggtcaacgagagcctcctcacgcccctcaacctggagatcgaccccaacgcgcagtgcgtgaagcaggaggagaaggagcagatcaagtccctcaacagcaggttcgcggccttcatcgacaaggtgcgcttcctggagcagcagaacaaactgctggagacaaagctgcagttctaccagaaccgcgagtgttgccagagcaacctggagcccctgtttgagggctacatcgagactctgcggcgggaggccgagtgcgtggaggccgacagcgggaggctggcctcagagcttaaccacgtgcaggaggtgctggagggctacaagaagaagtatgaggaggaggtttctctgagagcaacagctgagaacgagtttgtggctctgaagaaggatgtggactgcgcctacctccgcaaatcagacctggaggccaatgtggaggccctgatccaggagatcgacttcctgaggcggctgtatgaggaggagatccgcgttctccagtcccacatctcagacacctccgtggttgtcaagctggacaacagccgggacctgaacatggactgcatcattgccgagatcaaggcacagtacgatgacattgtcacccgtagccgggctgaggccgagtcctggtaccgcagcaagtgtgaggagatgaaggccacggtgatcaggcacggggagaccctgcgccgcaccaaggaggagatcaacgagctgaaccgcatgatccagaggctgacggctgaggtggagaatgccaagtgccagaattccaagctggaggctgcggtggctcagtctgagcagcagggtgaggcggccctcagcgatgcccgctgcaagttggccgagctggagggtgccctgcagaaggccaagcaggacatggcctgcctgatcagggagtaccaggaggtgatgaactccaagctgggcctggacatcgagatcgccacctacaggcgcctgctggagggcgaggagcagaggctgtgcgagggcgtcggctcggtgaatgtctgcgtcagcagctcccgcggtggcgttgtctgtggcgatctctgcgcctccactactgcccctgttgtctccaccagagtcagtagcgtccccagcaacagcaacgtggtggtgggcactactaacgcctgcgccccctccgcccgggttggcgtctgcggcggcagctgtaagaggtgctag
Sequence Length
1461
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
53,501 Da
NCBI Official Full Name
Homo sapiens keratin 86, mRNA
NCBI Official Synonym Full Names
keratin 86
NCBI Official Symbol
KRT86
NCBI Official Synonym Symbols
HB6; Hb1; K86; MNX; KRTHB1; KRTHB6
NCBI Protein Information
keratin, type II cuticular Hb6
UniProt Protein Name
Keratin, type II cuticular Hb6
Protein Family
UniProt Gene Name
KRT86
UniProt Synonym Gene Names
KRTHB6; K86
UniProt Entry Name
KRT86_HUMAN
NCBI Description
This gene encodes a type II keratin protein, which heterodimerizes with type I keratins to form hair and nails. This gene is present in a cluster of related genes and pseudogenes on chromosome 12. Mutations in this gene have been observed in patients with the hair disease monilethrix. [provided by RefSeq, Feb 2016]
Uniprot Description
K86: Defects in KRT86 are a cause of monilethrix (MLTRX). Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected. Belongs to the intermediate filament family.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: extracellular space
Molecular Function: protein binding
Disease: Monilethrix
Research Articles on KRT86
Similar Products
Product Notes
The KRT86 krt86 (Catalog #AAA1276423) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgacttgtg gatcttactg tggtggccgc gccttcagct gcatctcggc ctgcgggccc cggcccggcc gctgctgcat caccgccgcc ccctaccgtg gcatctcctg ctaccgcggc ctcaccgggg gcttcggcag ccacagcgtg tgcggaggct ttcgggccgg ctcctgcgga cgcagcttcg gctaccgctc cgggggcgtg tgcgggccca gtcccccatg catcaccacc gtgtcggtca acgagagcct cctcacgccc ctcaacctgg agatcgaccc caacgcgcag tgcgtgaagc aggaggagaa ggagcagatc aagtccctca acagcaggtt cgcggccttc atcgacaagg tgcgcttcct ggagcagcag aacaaactgc tggagacaaa gctgcagttc taccagaacc gcgagtgttg ccagagcaac ctggagcccc tgtttgaggg ctacatcgag actctgcggc gggaggccga gtgcgtggag gccgacagcg ggaggctggc ctcagagctt aaccacgtgc aggaggtgct ggagggctac aagaagaagt atgaggagga ggtttctctg agagcaacag ctgagaacga gtttgtggct ctgaagaagg atgtggactg cgcctacctc cgcaaatcag acctggaggc caatgtggag gccctgatcc aggagatcga cttcctgagg cggctgtatg aggaggagat ccgcgttctc cagtcccaca tctcagacac ctccgtggtt gtcaagctgg acaacagccg ggacctgaac atggactgca tcattgccga gatcaaggca cagtacgatg acattgtcac ccgtagccgg gctgaggccg agtcctggta ccgcagcaag tgtgaggaga tgaaggccac ggtgatcagg cacggggaga ccctgcgccg caccaaggag gagatcaacg agctgaaccg catgatccag aggctgacgg ctgaggtgga gaatgccaag tgccagaatt ccaagctgga ggctgcggtg gctcagtctg agcagcaggg tgaggcggcc ctcagcgatg cccgctgcaa gttggccgag ctggagggtg ccctgcagaa ggccaagcag gacatggcct gcctgatcag ggagtaccag gaggtgatga actccaagct gggcctggac atcgagatcg ccacctacag gcgcctgctg gagggcgagg agcagaggct gtgcgagggc gtcggctcgg tgaatgtctg cgtcagcagc tcccgcggtg gcgttgtctg tggcgatctc tgcgcctcca ctactgcccc tgttgtctcc accagagtca gtagcgtccc cagcaacagc aacgtggtgg tgggcactac taacgcctgc gccccctccg cccgggttgg cgtctgcggc ggcagctgta agaggtgcta g. It is sometimes possible for the material contained within the vial of "KRT86, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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