KRT17 cdna clone
KRT17
Gene Names
KRT17; PC; K17; PC2; 39.1; CK-17; PCHC1
Synonyms
KRT17; K17; PC; PC2; PCHC1; KRT17 cdna clone
Form/Format
Lyophilized
Sequence
Nucleotide Sequence: ATGACCACCTCCATCCGCCAGTTCACCTCCTCCAGCTCCATCAAGGGCTCCTCCGGCCTGGGGGGCGGCTCGTCCCGCACCTCCTGCCGGCTGTCTGGCGGCCTGGGTGCCGGCTCCTGCAGGCTGGGATCTGCTGGCGGCCTGGGCAGCACCCTCGGGGGTAGCAGCTACTCCAGCTGCTACAGCTTTGGCTCTGGTGGTGGCTATGGCAGCAGCTTTGGGGGTGTTGATGGGCTGCTGGCTGGAGGTGAGAAGGCCACCATGCAGAACCTCAATGACCGCCTGGCCTCCTACCTGGACAAGGTGCGTGCCCTGGAGGAGGCCAACACTGAGCTGGAGGTGAAGATCCGTGACTGGTACCAGAGGCAGGCCCCGGGGCCCGCCCGTGACTACAGCCAGTACTACAGGACAATTGAGGAGCTGCAGAACAAGATCCTCACAGCCACCGTGGACAATGCCAACATCCTGCTACAGATTGACAATGCCCGTCTGGCTGCTGATGACTTCCGCACCAAGTTTGAGACAGAGCAGGCCCTGCGCCTGAGTGTGGAGGCCGACATCAATGGCCTGCGCAGGGTGCTGGATGAGCTGACCCTGGCCAGAGCCGACCTGGAGATGCAGATTGAGAACCTCAAGGAGGAGCTGGCCTACCTGAAGAAGAACCACGAGGAGGAGATGAACGCCCTGCGAGGCCAGGTGGGTGGTGAGATCAATGTGGAGATGGACGCTGCCCCAGGCGTGGACCTGAGCCGCATCCTCAACGAGATGCGTGACCAGTATGAGAAGATGGCAGAGAAGAACCGCAAGGATGCCGAGGATTGGTTCTTCAGCAAGACAGAGGAACTGAACCGCGAGGTGGCCACCAACAGTGAGCTGGTGCAGAGTGGCAAGAGTGAGATCTCGGAGCTCCGGCGCACCATGCAGGCCTTGGAGATAGAGCTGCAGTCCCAGCTCAGCATGAAAGCATCCCTGGAGGGCAACCTGGCGGAGACAGAGAACCGCTACTGCGTGCAGCTGTCCCAGATCCAGGGGCTGATTGGCAGCGTGGAGGAGCAGCTGGCCCAGCTTCGCTGCGAGATGGAGCAGCAGAACCAGGAATACAAAATCCTGCTGGATGTGAAGACGCGGCTGGAGCAGGAGATTGCCACCTACCGCCGCCTGCTGGAGGGAGAGGATGCCCACCTGACTCAGTACAAGAAAGAACCGGTGACCACCCGTCAGGTGCGTACCATTGTGGAAGAGGTCCAGGATGGCAAGGTCATCTCCTCCCGCGAGCAGGTCCACCAGACCACCCGCTGA
Translation Sequence: MTTSIRQFTS SSSIKGSSGL GGGSSRTSCR LSGGLGAGSC RLGSAGGLGS TLGGSSYSSCYSFGSGGGYG SSFGGVDGLL AGGEKATMQN LNDRLASYLD KVRALEEANT ELEVKIRDWYQRQAPGPARD YSQYYRTIEE LQNKILTATV DNANILLQID NARLAADDFR TKFETEQALRLSVEADINGL RRVLDELTLA RADLEMQIEN LKEELAYLKK NHEEEMNALR GQVGGEINVEMDAAPGVDLS RILNEMRDQY EKMAEKNRKD AEDWFFSKTE ELNREVATNS ELVQSGKSEISELRRTMQAL EIELQSQLSM KASLEGNLAE TENRYCVQLS QIQGLIGSVE EQLAQLRCEMEQQNQEYKIL LDVKTRLEQE IATYRRLLEG EDAHLTQYKK EPVTTRQVRT IVEEVQDGKVISSREQVHQT TR
Translation Sequence: MTTSIRQFTS SSSIKGSSGL GGGSSRTSCR LSGGLGAGSC RLGSAGGLGS TLGGSSYSSCYSFGSGGGYG SSFGGVDGLL AGGEKATMQN LNDRLASYLD KVRALEEANT ELEVKIRDWYQRQAPGPARD YSQYYRTIEE LQNKILTATV DNANILLQID NARLAADDFR TKFETEQALRLSVEADINGL RRVLDELTLA RADLEMQIEN LKEELAYLKK NHEEEMNALR GQVGGEINVEMDAAPGVDLS RILNEMRDQY EKMAEKNRKD AEDWFFSKTE ELNREVATNS ELVQSGKSEISELRRTMQAL EIELQSQLSM KASLEGNLAE TENRYCVQLS QIQGLIGSVE EQLAQLRCEMEQQNQEYKIL LDVKTRLEQE IATYRRLLEG EDAHLTQYKK EPVTTRQVRT IVEEVQDGKVISSREQVHQT TR
Sequence Length
432
Species
Human
Chromosome Location
17q21.2
OMIM Reference Number
148069
cDNA Size
1299bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Vector
(puc19-derived cloning vector)
Preparation Before Usage
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
Preparation and Storage
Store the plasmid at -20 degree C.
Related Product Information for KRT17 cdna clone
KRT17 encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
Product Categories/Family for KRT17 cdna clone
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
keratin, type I cytoskeletal 17
NCBI Official Synonym Full Names
keratin 17
NCBI Official Symbol
KRT17
NCBI Official Synonym Symbols
PC; K17; PC2; 39.1; CK-17; PCHC1
NCBI Protein Information
keratin, type I cytoskeletal 17
UniProt Protein Name
Keratin, type I cytoskeletal 17
Protein Family
UniProt Gene Name
KRT17
UniProt Synonym Gene Names
CK-17; K17
UniProt Entry Name
K1C17_HUMAN
NCBI Description
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008]
Uniprot Description
K17: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K6.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component: cytoplasm; intermediate filament
Molecular Function: MHC class II receptor activity; protein binding; structural constituent of cytoskeleton; MHC class II protein binding
Biological Process: positive regulation of hair follicle development; epidermis development; hair follicle morphogenesis; positive regulation of translation; keratinization; intermediate filament organization; signal transduction; positive regulation of cell growth
Disease: Steatocystoma Multiplex; Pachyonychia Congenita 2
Research Articles on KRT17
Similar Products
Product Notes
The KRT17 krt17 (Catalog #AAA200659) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGACCACCT CCATCCGCCA GTTCACCTCC TCCAGCTCCA TCAAGGGCTC CTCCGGCCTG GGGGGCGGCT CGTCCCGCAC CTCCTGCCGG CTGTCTGGCG GCCTGGGTGC CGGCTCCTGC AGGCTGGGAT CTGCTGGCGG CCTGGGCAGC ACCCTCGGGG GTAGCAGCTA CTCCAGCTGC TACAGCTTTG GCTCTGGTGG TGGCTATGGC AGCAGCTTTG GGGGTGTTGA TGGGCTGCTG GCTGGAGGTG AGAAGGCCAC CATGCAGAAC CTCAATGACC GCCTGGCCTC CTACCTGGAC AAGGTGCGTG CCCTGGAGGA GGCCAACACT GAGCTGGAGG TGAAGATCCG TGACTGGTAC CAGAGGCAGG CCCCGGGGCC CGCCCGTGAC TACAGCCAGT ACTACAGGAC AATTGAGGAG CTGCAGAACA AGATCCTCAC AGCCACCGTG GACAATGCCA ACATCCTGCT ACAGATTGAC AATGCCCGTC TGGCTGCTGA TGACTTCCGC ACCAAGTTTG AGACAGAGCA GGCCCTGCGC CTGAGTGTGG AGGCCGACAT CAATGGCCTG CGCAGGGTGC TGGATGAGCT GACCCTGGCC AGAGCCGACC TGGAGATGCA GATTGAGAAC CTCAAGGAGG AGCTGGCCTA CCTGAAGAAG AACCACGAGG AGGAGATGAA CGCCCTGCGA GGCCAGGTGG GTGGTGAGAT CAATGTGGAG ATGGACGCTG CCCCAGGCGT GGACCTGAGC CGCATCCTCA ACGAGATGCG TGACCAGTAT GAGAAGATGG CAGAGAAGAA CCGCAAGGAT GCCGAGGATT GGTTCTTCAG CAAGACAGAG GAACTGAACC GCGAGGTGGC CACCAACAGT GAGCTGGTGC AGAGTGGCAA GAGTGAGATC TCGGAGCTCC GGCGCACCAT GCAGGCCTTG GAGATAGAGC TGCAGTCCCA GCTCAGCATG AAAGCATCCC TGGAGGGCAA CCTGGCGGAG ACAGAGAACC GCTACTGCGT GCAGCTGTCC CAGATCCAGG GGCTGATTGG CAGCGTGGAG GAGCAGCTGG CCCAGCTTCG CTGCGAGATG GAGCAGCAGA ACCAGGAATA CAAAATCCTG CTGGATGTGA AGACGCGGCT GGAGCAGGAG ATTGCCACCT ACCGCCGCCT GCTGGAGGGA GAGGATGCCC ACCTGACTCA GTACAAGAAA GAACCGGTGA CCACCCGTCA GGTGCGTACC ATTGTGGAAG AGGTCCAGGA TGGCAAGGTC ATCTCCTCCC GCGAGCAGGT CCACCAGACC ACCCGCTGA< br> Tra nslation Sequence: MTTSIRQFTS SSSIKGSSGL GGGSSRTSCR LSGGLGAGSC RLGSAGGLGS TLGGSSYSSC YSFGSGGGYG SSFGGVDGLL AGGEKATMQN LNDRLASYLD KVRALEEANT ELEVKIRDWY QRQAPGPARD YSQYYRTIEE LQNKILTATV DNANILLQID NARLAADDFR TKFETEQALR LSVEADINGL RRVLDELTLA RADLEMQIEN LKEELAYLKK NHEEEMNALR GQVGGEINVE MDAAPGVDLS RILNEMRDQY EKMAEKNRKD AEDWFFSKTE ELNREVATNS ELVQSGKSEI SELRRTMQAL EIELQSQLSM KASLEGNLAE TENRYCVQLS QIQGLIGSVE EQLAQLRCEM EQQNQEYKIL LDVKTRLEQE IATYRRLLEG EDAHLTQYKK EPVTTRQVRT IVEEVQDGKV ISSREQVHQT TR. It is sometimes possible for the material contained within the vial of "KRT17, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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