KIF11 cdna clone
KIF11 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008]
Uniprot Description
KIF11: a cytoskeletal protein that belongs to the kinesin-like protein family. BimC subfamily. Interacts with the thyroid hormone receptor in the presence of thyroid hormone. Plays a role in chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. Phosphorylation regulates its association with the spindle apparatus.
Protein type: Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: 10q24.1
Cellular Component: cytoplasm; cytosol; kinesin complex; membrane; microtubule; spindle; spindle microtubule; spindle pole
Molecular Function: microtubule motor activity; plus-end-directed microtubule motor activity; protein complex binding; protein kinase binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; chromosome segregation; microtubule-based movement; mitosis; mitotic spindle organization and biogenesis; regulation of mitotic centrosome separation; retrograde vesicle-mediated transport, Golgi to ER; spindle organization and biogenesis
Disease: Microcephaly With Or Without Chorioretinopathy, Lymphedema, Or Mental Retardation
Research Articles on KIF11
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Product Notes
The KIF11 kif11 (Catalog #AAA1274005) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcgtcgc agccaaattc gtctgcgaag aagaaagagg agaaggggaa gaacatccag gtggtggtga gatgcagacc atttaatttg gcagagcgga aagctagcgc ccattcaata gtagaatgtg atcctgtacg aaaagaagtt agtgtacgaa ctggaggatt ggctgacaag agctcaagga aaacatacac ttttgatatg gtgtttggag catctactaa acagattgat gtttaccgaa gtgttgtttg tccaattctg gatgaagtta ttatgggcta taattgcact atctttgcgt atggccaaac tggcactgga aaaactttta caatggaagg tgaaaggtca cctaatgaag agtatacctg ggaagaggat cccttggctg gtataattcc acgtaccctt catcaaattt ttgagaaact tactgataat ggtactgaat tttcagtcaa agtgtctctg ttggagatct ataatgaaga gctttttgat cttcttaatc catcatctga tgtttctgag agactacaga tgtttgatga tccccgtaac aagagaggag tgataattaa aggtttagaa gaaattacag tacacaacaa ggatgaagtc tatcaaattt tagaaaaggg ggcagcaaaa aggacaactg cagctactct gatgaatgca tactctagtc gttcccactc agttttctct gttacaatac atatgaaaga aactacgatt gatggagaag agcttgttaa aatcggaaag ttgaacttgg ttgatcttgc aggaagtgaa aacattggcc gttctggagc tgttgataag agagctcggg aagctggaaa tataaatcaa tccctgttga ctttgggaag ggtcattact gcccttgtag aaagaacacc tcatgttcct tatcgagaat ctaaactaac tagaatcctc caggattctc ttggagggcg tacaagaaca tctataattg caacaatttc tcctgcatct ctcaatcttg aggaaactct gagtacattg gaatatgctc atagagcaaa gaacatattg aataagcctg aagtgaatca gaaactcacc aaaaaagctc ttattaagga gtatacggag gagatagaac gtttaaaacg agatcttgct gcagcccgtg agaaaaatgg agtgtatatt tctgaagaaa attttagagt catgagtgga aaattaactg ttcaagaaga gcagattgta gaattgattg aaaaaattgg tgctgttgag gaggagctga atagggttac agagttgttt atggataata aaaatgaact tgaccagtgt aaatctgacc tgcaaaataa aacacaagaa cttgaaacca ctcaaaaaca tttgcaagaa actaaattac aacttgttaa agaagaatat atcacatcag ctttggaaag tactgaggag aaacttcatg atgctgccag caagctgctt aacacagttg aagaaactac aaaagatgta tctggtctcc attccaaact ggatcgtaag aaggcagttg accaacacaa tgcagaagct caggatattt ttggcaaaaa cctgaatagt ctgtttaata atatggaaga attaattaag gatggcagct caaagcaaaa ggccatgcta gaagtacata agaccttatt tggtaatctg ctgtcttcca gtgtctctgc attagatacc attactacag tagcacttgg atctctcaca tctattccag aaaatgtgtc tactcatgtt tctcagattt ttaatatgat actaaaagaa caatcattag cagcagaaag taaaactgta ctacaggaat tgattaatgt actcaagact gatcttctaa gttcactgga aatgatttta tccccaactg tggtgtctat actgaaaatc aatagtcaac taaagcatat tttcaagact tcattgacag tggccgataa gatagaagat caaaaaaagg aactagatgg ctttctcagt atactgtgta acaatctaca tgaactacaa gaaaatacca tttgttcctt ggttgagtca caaaagcaat gtggaaacct aactgaagac ctgaagacaa taaagcagac ccattcccag gaactttgca agttaatgaa tctttggaca gagagattct gtgctttgga ggaaaagtgt gaaaatatac agaaaccact tagtagtgtc caggaaaata tacagcagaa atctaaggat atagtcaaca aaatgacttt tcacagtcaa aaattttgtg ctgattctga tggcttctca caggaactca gaaattttaa ccaagaaggt acaaaattgg ttgaagaatc tgtgaaacac tctgataaac tcaatggcaa cctggaaaaa atatctcaag agactgaaca gagatgtgaa tctctgaaca caagaacagt ttatttttct gaacagtggg tatcttcctt aaatgaaagg gaacaggaac ttcacaactt attggaggtt gtaagccaat gttgtgaggc ttcaagttca gacatcactg agaaatcaga tggacgtaag gcagctcatg agaaacagca taacattttt cttgatcaga tgactattga tgaagataaa ttgatagcac aaaatctaga acttaatgaa accataaaaa ttggtttgac taagcttaat tgctttctgg aacaggatct gaaactggat atcccaacag gtacgacacc acagaggaaa agttatttat acccatcaac actggtaaga actgaaccac gtgaacatct ccttgatcag ctgaaaagga aacagcctga gctgttaatg atgctaaact gttcagaaaa caacaaagaa gagacaattc cggatgtgga tgtagaagag gcagttctgg ggcagtatac tgaagaacct ctaagtcaag agccatctgt agatgctggt gtggattgtt catcaattgg cggggttcca tttttccagc ataaaaaatc acatggaaaa gacaaagaaa acagaggcat taacacactg gagaggtcta aagtggaaga aactacagag cacttggtta caaagagcag attacctctg cgagcccaga tcaaccttta a. It is sometimes possible for the material contained within the vial of "KIF11, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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