ITGAX cdna clone
ITGAX cDNA Clone
Gene Names
ITGAX; CD11C; SLEB6
Synonyms
ITGAX; ITGAX cDNA Clone; ITGAX cdna clone
Sequence
atgaccaggaccagggcagcactcctcctgttcacagccttagcaacttctctaggtttcaacttggacacagaggagctgacagccttccgtgtggacagcgctgggtttggagacagcgtggtccagtatgccaactcctgggtggtggttggagccccccaaaagataacagctgccaaccaaacgggtggcctctaccagtgtggctacagcactggtgcctgtgagcccatcggcctgcaggtgcccccggaggccgtgaacatgtccctgggcctgtccctggcgtctaccaccagcccttcccagctgctggcctgcggccccaccgtgcaccacgagtgcgggaggaacatgtacctcaccggactctgcttcctcctgggccccacccagctcacccagaggctcccggtgtccaggcaggagtgcccaagacaggagcaggacattgtgttcctgatcgatggctcaggcagcatctcctcccgcaactttgccacgatgatgaacttcgtgagagctgtgataagccagttccagagacccagcacccagttttccctgatgcagttctccaacaaattccaaacacacttcactttcgaggaattcaggcgcagctcaaaccccctcagcctgttggcttctgttcaccagctgcaagggtttacatacacggccaccgccatccaaaatgtcgtgcaccgattgttccatgcctcatatggggcccgtagggatgccgccaaaattctcattgtcatcactgatgggaagaaagaaggcgacagcctggattataaggatgtcatccccatggctgatgcagcaggcatcatccgctatgcaattggggttggattagcttttcaaaacagaaattcttggaaagaattaaatgacattgcatcgaagccctcccaggaacacatatttaaagtggaggactttgatgctctgaaagatattcaaaaccaactgaaggagaagatctttgccattgagggtacggagaccacaagcagtagctccttcgaattggagatggcacaggagggcttcagcgctgtgttcacacctgatggccccgttctgggggctgtggggagcttcacctggtctggaggtgccttcctgtaccccccaaatatgagccctaccttcatcaacatgtctcaggagaatgtggacatgagggactcttacctgggttactccaccgagctggccctctggaaaggggtgcagagcctggtcctgggggccccccgctaccagcacaccgggaaggctgtcatcttcacccaggtgtccaggcaatggaggatgaaggccgaagtcacggggactcagatcggctcctacttcggggcctccctctgctccgtggacgtagacagcgacggcagcaccgacctggtcctcatcggggccccccattactacgagcagacccgagggggccaggtgtctgtgtgtcccttgcccagggggtggagaaggtggtggtgtgatgctgttctctacggggagcagggccacccctggggtcgctttggggcggctctgacagtgctgggggatgtgaatggggacaagctgacagacgtggtcatcggggccccaggagagaaggagaaccggggtgctgtctacctgtttcacggagtcttgggacccagcatcagcccctcccacagccagcggatcgcgggctcccagctctcctccaggctgcagtattttgggcaggcactgagcgggggtcaagacctcacccaggatggactggtggacctggctgtgggggcccggggccaggtgctcctgctcaggaccagacctgtgctctgggtgggggtgagcatgcagttcatacctgccgagatccccaggtctgcgtttgagtgtcgggagcaggtggtctctgagcagaccctggtacagtccaacatctgcctttacattgacaaacgttctaagaacctgcttgggagccgtgacctccaaagctctgtgaccttggacctggccctcgaccctggccgcctgagtccccgtgccaccttccaggaaacaaagaaccggagtctgagccgagtccgagtcctcgggctgaaggcacactgtgaaaacttcaacctgctgctcccgagctgcgtggaggactctgtgacccccattaccttgcgtctgaacttcacgctggtgggcaagcccctccttgccttcagaaacctgcggcctatgctggccgccgatgctcagagatacttcacggcctccctaccctttgagaagaactgtggagccgaccatatctgccaggacaatctcggcatctccttcagcttcccaggcttgaagtccctgctggtggggagtaacctggagctgaacgcagaagtgatggtgtggaatgacggggaagactcctacggaaccaccgtcaccttctcccaccccgcaggactgtcctaccgctacgtggcagagggccagaaacaagggcagctgcgttccctgcacctgacatgtgacagcgccccagttgggagccagggcacctggagcaccagctgcagaatcaaccacctcatcttccgtggcggcgcccagatcaccttcttggctacctttgacgtctcccccaaggctgtcctgggagaccggctgcttctgacagccaatgtgagcagtgagaacaacactcccaggaccagcaagaccaccttccagctggagctcccggtgaagtatgctgtctacactgtggttagcagccacgaacaattcaccaaatacctcaacttctcagagtctgaggagaaggaaagccatgtggccatgcacagataccaggtcaataacctgggacagagggacctgcctgtcagcatcaacttctgggtgcctgtggagctgaaccaggaggctgtgtggatggatgtggaggtctcccacccccagaacccatcccttcggtgctcctcagagaaaatcgcacccccagcatctgacttcctggcgcacattcagaagaatcccgtgctggactgctccattgctggctgcctgcggttccgctgtgacgtcccctccttcagcgtccaggaggagctggatttcaccctgaagggcaacctcagctttggctgggtccgccagatattgcagaagaaggtgtcggtcgtgagtgtggctgaaattacgttcgacacatccgtgtactcccagcttccaggacaggaggcatttatgagagctcagacgacaacggtgctggagaagtacaaggtccacaaccccacccccctcatcgtaggcagctccattgggggtctgttgctgctggcactcatcacagcggtactgtacaaagttggcttcttcaagcgtcagtacaaggaaatgatggaggaggcaaatggacaaattgccccagaaaacgggacacagacccccagcccgcccactccccattaccctcaggacaatgtctga
Sequence Length
3510
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
127,829 Da
NCBI Official Full Name
Homo sapiens integrin, alpha X (complement component 3 receptor 4 subunit), mRNA
NCBI Official Synonym Full Names
integrin subunit alpha X
NCBI Official Symbol
ITGAX
NCBI Official Synonym Symbols
CD11C; SLEB6
NCBI Protein Information
integrin alpha-X
UniProt Protein Name
Integrin alpha-X
Protein Family
UniProt Gene Name
ITGAX
UniProt Synonym Gene Names
CD11C
UniProt Entry Name
ITAX_HUMAN
NCBI Description
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Uniprot Description
ITGAX: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Belongs to the integrin alpha chain family.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: cell surface; membrane; plasma membrane
Molecular Function: protein binding; receptor activity
Biological Process: cell adhesion; extracellular matrix organization and biogenesis; heterotypic cell-cell adhesion; leukocyte migration; organ morphogenesis
Disease: Systemic Lupus Erythematosus
Research Articles on ITGAX
Similar Products
Product Notes
The ITGAX itgax (Catalog #AAA1266156) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaccagga ccagggcagc actcctcctg ttcacagcct tagcaacttc tctaggtttc aacttggaca cagaggagct gacagccttc cgtgtggaca gcgctgggtt tggagacagc gtggtccagt atgccaactc ctgggtggtg gttggagccc cccaaaagat aacagctgcc aaccaaacgg gtggcctcta ccagtgtggc tacagcactg gtgcctgtga gcccatcggc ctgcaggtgc ccccggaggc cgtgaacatg tccctgggcc tgtccctggc gtctaccacc agcccttccc agctgctggc ctgcggcccc accgtgcacc acgagtgcgg gaggaacatg tacctcaccg gactctgctt cctcctgggc cccacccagc tcacccagag gctcccggtg tccaggcagg agtgcccaag acaggagcag gacattgtgt tcctgatcga tggctcaggc agcatctcct cccgcaactt tgccacgatg atgaacttcg tgagagctgt gataagccag ttccagagac ccagcaccca gttttccctg atgcagttct ccaacaaatt ccaaacacac ttcactttcg aggaattcag gcgcagctca aaccccctca gcctgttggc ttctgttcac cagctgcaag ggtttacata cacggccacc gccatccaaa atgtcgtgca ccgattgttc catgcctcat atggggcccg tagggatgcc gccaaaattc tcattgtcat cactgatggg aagaaagaag gcgacagcct ggattataag gatgtcatcc ccatggctga tgcagcaggc atcatccgct atgcaattgg ggttggatta gcttttcaaa acagaaattc ttggaaagaa ttaaatgaca ttgcatcgaa gccctcccag gaacacatat ttaaagtgga ggactttgat gctctgaaag atattcaaaa ccaactgaag gagaagatct ttgccattga gggtacggag accacaagca gtagctcctt cgaattggag atggcacagg agggcttcag cgctgtgttc acacctgatg gccccgttct gggggctgtg gggagcttca cctggtctgg aggtgccttc ctgtaccccc caaatatgag ccctaccttc atcaacatgt ctcaggagaa tgtggacatg agggactctt acctgggtta ctccaccgag ctggccctct ggaaaggggt gcagagcctg gtcctggggg ccccccgcta ccagcacacc gggaaggctg tcatcttcac ccaggtgtcc aggcaatgga ggatgaaggc cgaagtcacg gggactcaga tcggctccta cttcggggcc tccctctgct ccgtggacgt agacagcgac ggcagcaccg acctggtcct catcggggcc ccccattact acgagcagac ccgagggggc caggtgtctg tgtgtccctt gcccaggggg tggagaaggt ggtggtgtga tgctgttctc tacggggagc agggccaccc ctggggtcgc tttggggcgg ctctgacagt gctgggggat gtgaatgggg acaagctgac agacgtggtc atcggggccc caggagagaa ggagaaccgg ggtgctgtct acctgtttca cggagtcttg ggacccagca tcagcccctc ccacagccag cggatcgcgg gctcccagct ctcctccagg ctgcagtatt ttgggcaggc actgagcggg ggtcaagacc tcacccagga tggactggtg gacctggctg tgggggcccg gggccaggtg ctcctgctca ggaccagacc tgtgctctgg gtgggggtga gcatgcagtt catacctgcc gagatcccca ggtctgcgtt tgagtgtcgg gagcaggtgg tctctgagca gaccctggta cagtccaaca tctgccttta cattgacaaa cgttctaaga acctgcttgg gagccgtgac ctccaaagct ctgtgacctt ggacctggcc ctcgaccctg gccgcctgag tccccgtgcc accttccagg aaacaaagaa ccggagtctg agccgagtcc gagtcctcgg gctgaaggca cactgtgaaa acttcaacct gctgctcccg agctgcgtgg aggactctgt gacccccatt accttgcgtc tgaacttcac gctggtgggc aagcccctcc ttgccttcag aaacctgcgg cctatgctgg ccgccgatgc tcagagatac ttcacggcct ccctaccctt tgagaagaac tgtggagccg accatatctg ccaggacaat ctcggcatct ccttcagctt cccaggcttg aagtccctgc tggtggggag taacctggag ctgaacgcag aagtgatggt gtggaatgac ggggaagact cctacggaac caccgtcacc ttctcccacc ccgcaggact gtcctaccgc tacgtggcag agggccagaa acaagggcag ctgcgttccc tgcacctgac atgtgacagc gccccagttg ggagccaggg cacctggagc accagctgca gaatcaacca cctcatcttc cgtggcggcg cccagatcac cttcttggct acctttgacg tctcccccaa ggctgtcctg ggagaccggc tgcttctgac agccaatgtg agcagtgaga acaacactcc caggaccagc aagaccacct tccagctgga gctcccggtg aagtatgctg tctacactgt ggttagcagc cacgaacaat tcaccaaata cctcaacttc tcagagtctg aggagaagga aagccatgtg gccatgcaca gataccaggt caataacctg ggacagaggg acctgcctgt cagcatcaac ttctgggtgc ctgtggagct gaaccaggag gctgtgtgga tggatgtgga ggtctcccac ccccagaacc catcccttcg gtgctcctca gagaaaatcg cacccccagc atctgacttc ctggcgcaca ttcagaagaa tcccgtgctg gactgctcca ttgctggctg cctgcggttc cgctgtgacg tcccctcctt cagcgtccag gaggagctgg atttcaccct gaagggcaac ctcagctttg gctgggtccg ccagatattg cagaagaagg tgtcggtcgt gagtgtggct gaaattacgt tcgacacatc cgtgtactcc cagcttccag gacaggaggc atttatgaga gctcagacga caacggtgct ggagaagtac aaggtccaca accccacccc cctcatcgta ggcagctcca ttgggggtct gttgctgctg gcactcatca cagcggtact gtacaaagtt ggcttcttca agcgtcagta caaggaaatg atggaggagg caaatggaca aattgcccca gaaaacggga cacagacccc cagcccgccc actccccatt accctcagga caatgtctga. It is sometimes possible for the material contained within the vial of "ITGAX, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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