ID1 cdna clone
ID1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
ID1: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor; DNA-binding
Chromosomal Location of Human Ortholog: 20q11
Cellular Component: Golgi apparatus; nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: angiogenesis; blood vessel endothelial cell migration; blood vessel morphogenesis; negative regulation of transcription factor activity; negative regulation of transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway
Research Articles on ID1
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Product Notes
The ID1 id1 (Catalog #AAA1272347) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaaagtcg ccagtggcag caccgccacc gccgccgcgg gccccagctg cgcgctgaag gccggcaaga cagcgagcgg tgcgggcgag gtggtgcgct gtctgtctga gcagagcgtg gccatctcgc gctgcgccgg gggcgccggg gcgcgcctgc ctgccctgct ggacgagcag caggtaaacg tgctgctcta cgacatgaac ggctgttact cacgcctcaa ggagctggtg cccaccctgc cccagaaccg caaggtgagc aaggtggaga ttctccagca cgtcatcgac tacatcaggg accttcagtt ggagctgaac tcggaatccg aagttggaac ccccgggggc cgagggctgc cggtccgggc tccgctcagc accctcaacg gcgagatcag cgccctgacg gccgaggcgg catgcgttcc tgcggacgat cgcatcttgt gtcgctga. It is sometimes possible for the material contained within the vial of "ID1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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