GPR68 cdna clone
GPR68 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
GPR68: Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Tumor suppressor; Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 14q31
Cellular Component: integral to plasma membrane; plasma membrane
Biological Process: inflammatory response
Research Articles on GPR68
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Product Notes
The GPR68 gpr68 (Catalog #AAA1277441) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGAGGAGTG TGGCCCCTTC AGGCCCAAAG ATGGGGAACA TCACTGCAGA CAACTCCTCG ATGAGCTGTA CCATCGACCA TACCATCCAC CAGACGCTGG CCCCGGTGGT CTATGTTACC GTGCTGGTGG TGGGCTTCCC GGCCAACTGC CTGTCCCTCT ACTTCGGCTA CCTGCAGATC AAGGCCCGGA ACGAGCTGGG CGTGTACCTG TGCAACCTGA CGGTGGCCGA CCTCTTCTAC ATCTGCTCGC TGCCCTTCTG GCTGCAGTAC GTGCTGCAGC ACGACAACTG GTCTCACGGC GACCTGTCCT GCCAGGTGTG CGGCATCCTC CTGTACGAGA ACATCTACAT CAGCGTGGGC TTCCTCTGCT GCATCTCCGT GGACCGCTAC CTGGCTGTGG CCCATCCCTT CCGCTTCCAC CAGTTCCGGA CCCTGAAGGC GGCCGTCGGC GTCAGCGTGG TCATCTGGGC CAAGGAGCTG CTGACCAGCA TCTACTTCCT GATGCACGAG GAGGTCATCG AGGACGAGAA CCAGCACCGC GTGTGCTTTG AGCACTACCC CATCCAGGCA TGGCAGCGCG CCATCAACTA CTACCGCTTC CTGGTGGGCT TCCTCTTCCC CATCTGCCTG CTGCTGGCGT CCTACCAGGG CATCCTGCGC GCCGTGCGCC GGAGCCACGG CACCCAGAAG AGCCGCAAGG ACCAGATCCA GCGGCTGGTG CTCAGCACCG TGGTCATCTT CCTGGCCTGC TTCCTGCCCT ACCACGTGTT GCTGCTGGTG CGCAGCGTCT GGGAGGCCAG CTGCGACTTC GCCAAGGGCG TTTTCAACGC CTACCACTTC TCCCTCCTGC TCACCAGCTT CAACTGCGTC GCCGACCCCG TGCTCTACTG CTTCGTCAGC GAGACCACCC ACCGGGACCT GGCCCGCCTC CGCGGGGCCT GCCTGGCCTT CCTCACCTGC TCCAGGACCG GCCGGGCCAG GGAGGCCTAC CCGCTGGGTG CCCCCGAGGC CTCCGGGAAA AGCGGGGCCC AGGGTGAGGA GCCCGAGCTG TTGACCAAGC TCCACCCGGC CTTCCAGACC CCTAACTCGC CAGGGTCGGG CGGGTTCCCC ACGGGCAGGT TGGCCTAG. It is sometimes possible for the material contained within the vial of "GPR68, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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