Rabbit anti-Human OGR1/GPR68 Polyclonal Antibody | anti-OGR1/GPR68 antibody
OGR1/GPR68
NCBI and Uniprot Product Information
Uniprot Description
Function: Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer
By similarity. Ref.8 Ref.10
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system. Ref.10
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Caution: Was originally (Ref.8) thought to be a receptor for sphingosylphosphorylcholine (SPC). However, this work has been retracted (Ref.9).
Sequence caution: The sequence AAH96071.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH96072.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH96073.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH96074.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH98567.1 differs from that shown. Reason: Erroneous initiation. The sequence AAT38917.1 differs from that shown. Reason: Erroneous initiation. The sequence ACG60649.1 differs from that shown. Reason: Erroneous initiation. The sequence EAW81447.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on OGR1/GPR68
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Product Notes
The OGR1/GPR68 gpr68 (Catalog #AAA395776) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OGR1/GPR68 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's OGR1/GPR68 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Iimmunohistochemistry (IHC), Neutralization. Researchers should empirically determine the suitability of the OGR1/GPR68 gpr68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OGR1/GPR68, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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