GNB2L1 cdna clone
GNB2L1 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
RACK1: a G-beta like protein containing 7 WD domains. A presumptive scaffold protein, linking protein kinase C to its substrates. Binds inositol 1,4,5-trisphosphate receptors and regulates Ca2+ release by enhancing inositol 1,4,5-trisphosphate receptor binding affinity for inositol 1,4,5-trisphosphate. An insulin-like growth factor 1 receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.
Protein type: Nuclear receptor co-regulator; G protein, heterotrimeric; Adaptor/scaffold; G protein; G protein, heterotrimeric beta; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q35.3
Cellular Component: cell soma; cell-cell adherens junction; cytoplasm; cytosol; dendrite; midbody; mitochondrion; nucleus; perinuclear region of cytoplasm; phagocytic cup; small ribosomal subunit
Molecular Function: caspase activator activity; enzyme binding; ion channel inhibitor activity; protein binding; protein complex scaffold; protein homodimerization activity; protein kinase C binding; protein phosphatase binding; protein tyrosine kinase inhibitor activity; receptor tyrosine kinase binding; SH2 domain binding
Biological Process: caspase activation; negative regulation of cell growth; negative regulation of peptidyl-serine phosphorylation; negative regulation of phagocytosis; negative regulation of protein kinase B signaling cascade; negative regulation of translation; negative regulation of Wnt receptor signaling pathway; positive regulation of apoptosis; positive regulation of cAMP catabolic process; positive regulation of cell migration; positive regulation of cyclic-nucleotide phosphodiesterase activity; positive regulation of Golgi to plasma membrane protein transport; positive regulation of GTPase activity; positive regulation of mitochondrial depolarization; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein amino acid phosphorylation; positive regulation of protein homooligomerization; regulation of cell cycle; regulation of cell division; regulation of protein localization
Research Articles on GNB2L1
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Product Notes
The GNB2L1 rack1 (Catalog #AAA1276898) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgactgagc agatgaccct tcgtggcacc ctcaagggcc acaacggctg ggtaacccag atcgctacta ccccgcagtt cccggacatg atcctctccg cctctcgaga taagaccatc atcatgtgga aactgaccag ggatgagacc aactatggaa ttccacagcg tgctctgcgg ggtcactccc actttgttag tgatgtggtt atctcctcag atggccagtt tgccctctca ggctcctggg atggaaccct gcgcctctgg gatctcacaa cgggcaccac cacgaggcga tttgtgggcc ataccaagga tgtgctgagt gtggccttct cctctgacaa ccggcagatt gtctctggat ctcgagataa aaccatcaag ctatggaata ccctgggtgt gtgcaaatac actgtccagg atgagagcca ctcagagtgg gtgtcttgtg tccgcttctc gcccaacagc agcaacccta tcatcgtctc ctgtggctgg gacaagctgg tcaaggtatg gaacctggct aactgcaagc tgaagaccaa ccacattggc cacacaggct atctgaacac ggtgactgtc tctccagatg gatccctctg tgcttctgga ggcaaggatg gccaggccat gttatgggat ctcaacgaag gcaaacacct ttacacgcta gatggtgggg acatcatcaa cgccctgtgc ttcagcccta accgctactg gctgtgtgct gccacaggcc ccagcatcaa gatctgggat ttagagggaa agatcattgt agatgaactg aagcaagaag ttatcagtac cagcagcaag gcagaaccac cccagtgcac ctccctggcc tggtctgctg atggccagac tctgtttgct ggctacacgg acaacctggt gcgagtgtgg caggtgacca ttggcacacg ctag. It is sometimes possible for the material contained within the vial of "GNB2L1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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