GEMIN5 cdna clone
GEMIN5 cDNA Clone
Gene Names
GEMIN5; GEMIN-5
Synonyms
GEMIN5; GEMIN5 cDNA Clone; GEMIN5 cdna clone
Sequence
atggggcaggagccgcggacgctgccgccctcccccaactggtactgcgcccgctgcagcgatgccgtgcccgggggcctctttggcttcgccgcgcggacctccgtcttccttgtccgcgtgggcccgggcgcaggcgagagtccagggacacccccgtttcgagtcataggagagttggtgggacacaccgaaagggtctctggcttcacattttctcatcaccctggtcagtacaacctctgtgccaccagctccgacgatgggactgtgaaaatatgggatgtagagacaaaaacagttgtgacagaacatgcactccatcagcatacgatatcaacattacattggtctcctcgagtaaaggacttaatagtatctggggatgaaaaaggagtagttttctgttactggtttaacagaaatgacagccagcacctctttatagaacccaggacaattttctgtcttacttgttcacctcatcatgaagatttagtagccattggctacaaggatggcatagtggtgataattgacatcagtaagaaaggagaagttattcataggcttcgaggccatgatgatgaaatccactccatagcctggtgtcccctgcctggtgaagattgtttatctataaaccaagaggaaacttcagaagaagctgaaattaccaacgggaatgctgtagcacaagctccagtaacaaaaggttgctacttagccactggaagcaaagatcaaaccattcgaatctggagctgttctagaggccgaggggtgatgattttgaaattgccctttctgaagagaagaggagggggtatagacccaactgttaaagagcgcctttggttgacactccattggcccagcaatcaaccaacacagctggtatctagctgttttggaggtgaactgttgcaatgggatctcactcaatcttggagacggaaatacaccctcttcagtgcctcatcagaagggcaaaatcattcaagaattgtgtttaatttatgtcctttacaaacagaggatgacaaacagctgttactttctacatcaatggatagagatgtaaaatgttgggacatagccaccttggagtgcagctggacccttccttcccttggtgggtttgcatacagcctggctttctcttctgtggacataggctctttggccataggtgttggggatggcatgatccgtgtatggaatacactctccataaagaacaactatgatgtgaaaaatttttggcaaggcgtgaagtccaaggttacagcgctgtgctggcacccaaccaaggaaggttgcttagcttttggaactgatgatggaaaagtgggattgtatgacacctactccaacaagcctccacagatttctagcacatatcataagaagactgtatatacgttagcctgggggccaccagtaccccccatgtcacttggaggagaaggagacagaccttcccttgctttatacagctgtggaggagaagggattgtcttacagcataatccctggaagcttagtggagaagcctttgacatcaacaaactcatcagggacaccaattcaatcaaatacaaattgcctgtacacacagagataagttggaaagcagatggcaaaatcatggctcttggcaatgaagatggatcaatagaaatatttcagattcccaacctgaaactgatctgtactatccaacagcatcacaagcttgtgaataccattagctggcatcatgagcatggcagccagccagaattgagctatctgatggcctctggctccaacaatgcagtcatttacgtgcacaacctgaagactgtcatagagagcagccctgagtctccagtgaccattacagagccctaccggaccctctcagggcatacggccaagattaccagtgtggcgtggagcccacatcatgatggaaggctggtatctgcttcctatgatggtacagcccaggtgtgggatgctctccgggaagagcccctgtgcaatttccgaggacatcaaggtcgactgctttgtgtggcatggtctcctttggatccagactgcatctattcaggggcagatgacttttgtgtgcacaagtggctcacttccatgcaagatcattcccggcctcctcaaggcaaaaaaagtattgaattggagaaaaaacggctctctcaacctaaggcaaagcccaaaaagaagaaaaagcccaccttgagaactcctgtaaagctggaatcgattgatggaaatgaagaagaaagcatgaaggagaactcaggacctgttgagaatggtgtgtcagaccaagaaggggaggagcaagcacgggagccggaattaccctgtggccttgctccagcggtttctagagaaccagttatctgcactccagtttcctcaggctttgaaaagtcaaaagtcaccattaataacaaagtcattttactgaaaaaggagccaccaaaagagaagccagaaaccttaatcaagaagagaaaagctcgttccttgcttcccctgagtacaagcctggaccacagatccaaagaggagcttcatcaggactgtttggtactagcaactgcaaagcactccagagagctgaatgaagatgtgtctgctgatgttgaggaaagatttcatctggggcttttcacagacagggctaccctgtatagaatgattgatattgaaggaaaaggtcacttagaaaatggccaccctgagttatttcaccagcttatgctttggaaaggagatctcaaaggtgttctccagactgcagcagaaagaggggagctgacagacaaccttgtggctatggcaccagcagctggctaccatgtgtggctatgggctgtggaagcttttgccaaacagctgtgttttcaggatcagtatgtcaaggctgcttctcacctactttccatccacaaagtgtatgaagcggtggagctgctcaagtcaaaccatttttacagggaagctattgcgattgccaaggcccggctgcgcccggaggacccagtcctgaaggacttgtacctcagctggggaaccgtcctagaaagagatggccactatgctgtagctgccaaatgctatttaggggccacttgtgcttatgatgcagccaaagttttggccaaaaagggggatgcggcatcacttagaacggctgcagagttggctgccatcgtaggagaggatgagttgtctgcttccctggctctcagatgtgcccaagagctgcttctggccaacaactgggtgggagcccaggaagccctgcagctgcatgaaagtctacagggtcagagattggtgttttgccttctggagctactgtccaggcatctggaggaaaagcagctttcagagggcaaaagctcctcctcttaccacacttggaacacgggcaccgaagggcctttcgtggagagggtgactgcagtgtggaagagcatcttcagccttgacacccctgagcagtatcaggaagcctttcagaagctgcagaacatcaagtacccatctgctacaaataacacacctgccaaacagctcctgcttcacatttgccatgacttgaccctggcagtgctgagccaacagatggcctcctgggacgaggctgtgcaggcgctccttcgggcggtggtccggagctatgactcagggagcttcaccatcatgcaggaagtgtactcagcctttctccctgatggctgtgaccacctaagagacaagttgggggaccatcaatcccctgccacaccagctttcaaaagtttggaggccttttttctttatgggcgtctgtatgaattctggtggtctctctccagaccttgcccaaattccagtgtctgggtaagggctggtcacagaacactctctgttgagccaagccagcagttagacactgccagcactgaagaaacggaccctgaaacttctcagccagagccaaacaggccttcagaactagacttgagactcacagaagaaggtgagcgaatgctgagtacttttaaggagctcttttcagaaaagcatgccagtctccaaaactcacagagaactgttgctgaagtccaagagaccttggcagaaatgatccgacaacaccaaaagagtcaactctgtaaatccacagcaaatggtcctgataagaatgaaccggaagtagaagcagagcagcccctctgcagttctcagagccagtgtaaagaagaaaaaaatgagccactttctctgcctgagttaaccaaaaggcttaccgaggcaaatcagagaatggcaaaatttcctgagagcattaaggcctggcccttcccagatgtgctggagtgctgcctcgtcctgcttctcatcaggtcccactttcctggctgtctggcccaggaaatgcagcagcaggcccaagagctccttcagaaatacggcaacacgaaaacttacagaagacactgccagaccttctgtatgtga
Sequence Length
4527
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
168,589 Da
NCBI Official Full Name
Homo sapiens gem (nuclear organelle) associated protein 5, mRNA
NCBI Official Synonym Full Names
gem nuclear organelle associated protein 5
NCBI Official Symbol
GEMIN5
NCBI Official Synonym Symbols
GEMIN-5
NCBI Protein Information
gem-associated protein 5
UniProt Protein Name
Gem-associated protein 5
Protein Family
UniProt Gene Name
GEMIN5
UniProt Synonym Gene Names
Gemin5
UniProt Entry Name
GEMI5_HUMAN
NCBI Description
This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Uniprot Description
GEMIN5: the snRNA-binding protein of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm.
Protein type: RNA-binding; Nuclear receptor co-regulator; RNA processing; RNA splicing
Chromosomal Location of Human Ortholog: 5q33.2
Cellular Component: cytoplasm; cytosol; membrane; nuclear body; nucleoplasm; nucleus; SMN complex
Molecular Function: protein binding; snRNA binding
Biological Process: nuclear import; nuclear mRNA splicing, via spliceosome; protein complex assembly; spliceosomal snRNP biogenesis
Research Articles on GEMIN5
Similar Products
Product Notes
The GEMIN5 gemin5 (Catalog #AAA1272031) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggggcagg agccgcggac gctgccgccc tcccccaact ggtactgcgc ccgctgcagc gatgccgtgc ccgggggcct ctttggcttc gccgcgcgga cctccgtctt ccttgtccgc gtgggcccgg gcgcaggcga gagtccaggg acacccccgt ttcgagtcat aggagagttg gtgggacaca ccgaaagggt ctctggcttc acattttctc atcaccctgg tcagtacaac ctctgtgcca ccagctccga cgatgggact gtgaaaatat gggatgtaga gacaaaaaca gttgtgacag aacatgcact ccatcagcat acgatatcaa cattacattg gtctcctcga gtaaaggact taatagtatc tggggatgaa aaaggagtag ttttctgtta ctggtttaac agaaatgaca gccagcacct ctttatagaa cccaggacaa ttttctgtct tacttgttca cctcatcatg aagatttagt agccattggc tacaaggatg gcatagtggt gataattgac atcagtaaga aaggagaagt tattcatagg cttcgaggcc atgatgatga aatccactcc atagcctggt gtcccctgcc tggtgaagat tgtttatcta taaaccaaga ggaaacttca gaagaagctg aaattaccaa cgggaatgct gtagcacaag ctccagtaac aaaaggttgc tacttagcca ctggaagcaa agatcaaacc attcgaatct ggagctgttc tagaggccga ggggtgatga ttttgaaatt gccctttctg aagagaagag gagggggtat agacccaact gttaaagagc gcctttggtt gacactccat tggcccagca atcaaccaac acagctggta tctagctgtt ttggaggtga actgttgcaa tgggatctca ctcaatcttg gagacggaaa tacaccctct tcagtgcctc atcagaaggg caaaatcatt caagaattgt gtttaattta tgtcctttac aaacagagga tgacaaacag ctgttacttt ctacatcaat ggatagagat gtaaaatgtt gggacatagc caccttggag tgcagctgga cccttccttc ccttggtggg tttgcataca gcctggcttt ctcttctgtg gacataggct ctttggccat aggtgttggg gatggcatga tccgtgtatg gaatacactc tccataaaga acaactatga tgtgaaaaat ttttggcaag gcgtgaagtc caaggttaca gcgctgtgct ggcacccaac caaggaaggt tgcttagctt ttggaactga tgatggaaaa gtgggattgt atgacaccta ctccaacaag cctccacaga tttctagcac atatcataag aagactgtat atacgttagc ctgggggcca ccagtacccc ccatgtcact tggaggagaa ggagacagac cttcccttgc tttatacagc tgtggaggag aagggattgt cttacagcat aatccctgga agcttagtgg agaagccttt gacatcaaca aactcatcag ggacaccaat tcaatcaaat acaaattgcc tgtacacaca gagataagtt ggaaagcaga tggcaaaatc atggctcttg gcaatgaaga tggatcaata gaaatatttc agattcccaa cctgaaactg atctgtacta tccaacagca tcacaagctt gtgaatacca ttagctggca tcatgagcat ggcagccagc cagaattgag ctatctgatg gcctctggct ccaacaatgc agtcatttac gtgcacaacc tgaagactgt catagagagc agccctgagt ctccagtgac cattacagag ccctaccgga ccctctcagg gcatacggcc aagattacca gtgtggcgtg gagcccacat catgatggaa ggctggtatc tgcttcctat gatggtacag cccaggtgtg ggatgctctc cgggaagagc ccctgtgcaa tttccgagga catcaaggtc gactgctttg tgtggcatgg tctcctttgg atccagactg catctattca ggggcagatg acttttgtgt gcacaagtgg ctcacttcca tgcaagatca ttcccggcct cctcaaggca aaaaaagtat tgaattggag aaaaaacggc tctctcaacc taaggcaaag cccaaaaaga agaaaaagcc caccttgaga actcctgtaa agctggaatc gattgatgga aatgaagaag aaagcatgaa ggagaactca ggacctgttg agaatggtgt gtcagaccaa gaaggggagg agcaagcacg ggagccggaa ttaccctgtg gccttgctcc agcggtttct agagaaccag ttatctgcac tccagtttcc tcaggctttg aaaagtcaaa agtcaccatt aataacaaag tcattttact gaaaaaggag ccaccaaaag agaagccaga aaccttaatc aagaagagaa aagctcgttc cttgcttccc ctgagtacaa gcctggacca cagatccaaa gaggagcttc atcaggactg tttggtacta gcaactgcaa agcactccag agagctgaat gaagatgtgt ctgctgatgt tgaggaaaga tttcatctgg ggcttttcac agacagggct accctgtata gaatgattga tattgaagga aaaggtcact tagaaaatgg ccaccctgag ttatttcacc agcttatgct ttggaaagga gatctcaaag gtgttctcca gactgcagca gaaagagggg agctgacaga caaccttgtg gctatggcac cagcagctgg ctaccatgtg tggctatggg ctgtggaagc ttttgccaaa cagctgtgtt ttcaggatca gtatgtcaag gctgcttctc acctactttc catccacaaa gtgtatgaag cggtggagct gctcaagtca aaccattttt acagggaagc tattgcgatt gccaaggccc ggctgcgccc ggaggaccca gtcctgaagg acttgtacct cagctgggga accgtcctag aaagagatgg ccactatgct gtagctgcca aatgctattt aggggccact tgtgcttatg atgcagccaa agttttggcc aaaaaggggg atgcggcatc acttagaacg gctgcagagt tggctgccat cgtaggagag gatgagttgt ctgcttccct ggctctcaga tgtgcccaag agctgcttct ggccaacaac tgggtgggag cccaggaagc cctgcagctg catgaaagtc tacagggtca gagattggtg ttttgccttc tggagctact gtccaggcat ctggaggaaa agcagctttc agagggcaaa agctcctcct cttaccacac ttggaacacg ggcaccgaag ggcctttcgt ggagagggtg actgcagtgt ggaagagcat cttcagcctt gacacccctg agcagtatca ggaagccttt cagaagctgc agaacatcaa gtacccatct gctacaaata acacacctgc caaacagctc ctgcttcaca tttgccatga cttgaccctg gcagtgctga gccaacagat ggcctcctgg gacgaggctg tgcaggcgct ccttcgggcg gtggtccgga gctatgactc agggagcttc accatcatgc aggaagtgta ctcagccttt ctccctgatg gctgtgacca cctaagagac aagttggggg accatcaatc ccctgccaca ccagctttca aaagtttgga ggcctttttt ctttatgggc gtctgtatga attctggtgg tctctctcca gaccttgccc aaattccagt gtctgggtaa gggctggtca cagaacactc tctgttgagc caagccagca gttagacact gccagcactg aagaaacgga ccctgaaact tctcagccag agccaaacag gccttcagaa ctagacttga gactcacaga agaaggtgag cgaatgctga gtacttttaa ggagctcttt tcagaaaagc atgccagtct ccaaaactca cagagaactg ttgctgaagt ccaagagacc ttggcagaaa tgatccgaca acaccaaaag agtcaactct gtaaatccac agcaaatggt cctgataaga atgaaccgga agtagaagca gagcagcccc tctgcagttc tcagagccag tgtaaagaag aaaaaaatga gccactttct ctgcctgagt taaccaaaag gcttaccgag gcaaatcaga gaatggcaaa atttcctgag agcattaagg cctggccctt cccagatgtg ctggagtgct gcctcgtcct gcttctcatc aggtcccact ttcctggctg tctggcccag gaaatgcagc agcaggccca agagctcctt cagaaatacg gcaacacgaa aacttacaga agacactgcc agaccttctg tatgtga. It is sometimes possible for the material contained within the vial of "GEMIN5, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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