FMNL2 cdna clone
FMNL2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Uniprot Description
FMNL2: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics. Belongs to the formin homology family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 2q23.3
Cellular Component: cell-cell adherens junction; cytosol
Biological Process: cortical actin cytoskeleton organization and biogenesis; cytoskeleton organization and biogenesis; regulation of cell morphogenesis