EXPH5 cdna clone
EXPH5 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the synaptotagmin-like protein (Slp) family lacking a C2 domain. It contains an N-terminal synaptotagmin-like homology domain (SHD), and is a ras-related protein Rab-27B effector protein. This protein is thought to be involved in exosome secretion and intracellular vesicle trafficking. Reduced expression of this gene results in keratin filament defects. Mutations in this gene have been associated with some cases of epidermolysis bullosa, an inherited skin fragility disorder. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Uniprot Description
exophilin 5: May act as Rab effector protein and play a role in vesicle trafficking. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs; GAPs, Rab
Chromosomal Location of Human Ortholog: 11q22.3
Cellular Component: endosome
Molecular Function: Rab GTPase binding
Biological Process: positive regulation of exocytosis; positive regulation of protein secretion
Disease: Epidermolysis Bullosa, Nonspecific, Autosomal Recessive
Research Articles on EXPH5
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Product Notes
The EXPH5 exph5 (Catalog #AAA1271824) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGACGAAAG TTCCTCCGGC GTTTGATTTC AGTTTCTTAA ATGACGAAGA GGCCGGGAAG ATCCTTCAGG TGCTGGAAAG GAATGAGGAG TTACAGAGGG CCGAGAAGGA CAGGATCAGC AAACTTCAGA AGACAAAGAG GGATATCAGA TGGCTTCAGG GAGTGACTGG TGAATGGTTT GAAGAAATTC AAAGAAAAAA GTTTTGCAAT GAAACAGATG TTAGCCAAAT GTTAAAACAA CCACTTACAT ACAGGCTAAG TAAGGAGATG GCAAAAAATG ATCCGATAGA ATTACCTACA TCAAGATCTA AAAATGTAAC TAATCAAAAA AAGCCGACAC CTTTTTCTTC CCGGATGAGC TTCAGATCGT CATTTGCTTC CCTGTTCTCA TTCAGGAAAT CTGGAAAGGA GACTTCAAAG CTTCCATCAC TGGGACAGAA AGGATGTGAT GGCCATGCAG GACCTCCTAT GCCTGTGAGG GGAGCTGCTG TGCAGGCAAA AATATACAAT TCACCTCTGG AAAATCATCT AGTTGACAGT ACATTTGTCC CAAAGCCAGC AGTCATGAGG GAGGAGAGTG GCATGCCTCC ACCGTGGGAT GCTTCACTGC TGGAGAATGA GTTTTTCCAA GTTTTAGATG ACTTGGATAG CAAATTGGCT CAGGAACAGT CTGCAAGCTC AGTGAATACC AGAACACCCC TCAACTATGG ATCAAGAACA CAGTTCGGTC ACTTTTATTC CAGTGGTAAC AGACATGGTA ATATCACAGA AAGGCACAAA AAACACTATA ATGAAACTTC CAATATGTCT ATCTATGACA TCCTAAGACC AGGAACTCCT AGGGAAGGTT TTAAAACCTT TTCTCCTAGG ACAAGCACAA TTTATGATAT GTATAGGACA AGGGAGCCCA GAGTCTTTAA AGAAGATTAT GTGCAAAAGA ATACTTTTGG CAGTACTTCG CTGTGTTTTG ACAGCAGGCA ACGGTCGGCC TTACCAGCCA CAGGGCATTT CACAGCAAGA AGCTTACATT TTCCAGCCAC AACTCAGAGC AAGAGTGGGT TTATACCACC AAGGCACCAG CAGAGTCCAA AGAGAACTCC TTTATCATCC ATCATATGGA ACAGATCAGA TTCCTCTAGA GACAGGGAGA ACCAGGAAGA GTTCCTGAGG GCACCATCAC CAATGGAAAT TGATCCCGCT GACAAGTATG TGTATCCCAG GGGTTTTCAG GAGAATAAGA GATATGAATC GTACCATTCA CAGAATGTTT ACCAACGTGT TAGTTTAAAT GCTCCCATGG AGAATGCAAT GAGTCCCGAC ACTTTTGAGA ACTCAGAGAA CATGCCATTC TACCATCAAA GCAACACATT TACCAGATCT TTCTTCAGCA ATACCTTTGG ACGAAGCGGA GAACAGAGGA GATTTGGACA AGGTCCTTTT TGGGGCCAAG AGAAAGGACA TTCTTTCTGG TCTGACTTTC ATCGAAGCAG GAAATCATTC AGTTCTTCTG ACAGAGACTT TGAAATGATT TCCATGGAAG CAAATAGTGT ATCAGCCATT CATGGCCATA ATGTTTCTTC TGAACACTGG GAATCATTTT CTTCTGGTTA TGGAACAGAT GTTTCCAGAG GCCAAGAAGA GCCACATCCT TGGCAGTTTG ATTTTCAGAG ATCCACACTG GATAGCATGG TGGTATCACA TGGTAATGAG ACCCAGTTGA CTCCTCATTT TGGCACACCA AATGTTTGCT CCATGACTGG TTCAAGCTAT CACGTCAAAT CTAGTGAGTT GGTAAGTCAA CAGGACAGTT CTCCTGTAGA AGTACATATA AACAAAGAAG CTTCCTCATT TGGAATTGCT CAGACTCTAG CATCCTCATT CAAAACTTCC TTTTCCCAGA TTTCTGATGA CAGAAGGAAT CCTCAGAGTC CCAACTTGCA GAATCCCACA GTCACTTTGC AGAAAATTTT TCCAAATAAG CCTGCCTCTC ATCCAATGAG AAGCCATACA GAAGTCACTG TGACCAACAG CAATTCAGTT GACTCTCTGC CTCTTGCCAA AAGCCAGCCC AATATCTTGG TCACAGAAGT AAATAATGAG AAAGACTTAA ATGAATCTAT TTCAGAAGAA GACAAACAGC TAAGCAAGAT GGACCAGACA AACAAGGCAG GTGAAATACC CCAACCTGTT TCACAGACAG GGATCTCAAA CTCTTTACCT GATTTTCAAA ATCCCTTATC CCAGGACTCA GCCAAGAGCA ACGGGTTTGG TTTTAATGCA TCTACCATAA TAAGTTCAAA AAAGTCACCC AGAGTCTTTT CCAGGAAAGA TACCTCCAAA ATGTATATAC CGCACACAGA TAAATCCAAT GACATTAAAC AAGATAAGAG GTTTACTGAA AACAGAAAAC TTGGCTCAAC AGCTTCCCTT CCTTTCATTC AGGAACACAG AACACCACCA TCTTTCCCCA GGACAGACCA AGGTTGTCAC CAGGAATTAA CTGTAAATAA TGAAGATATT TCAAGAATTA TTACAAATAA CCACTGGAGC TCTGCACTGA CTGATACTCA AAATGCACAA TACTCAAAAT GCAAGTTAAC TCCTGGCCAC AAGACCTCGT GTGATTCTTT AGATCTGTCA TCAGCTGCAC TACCAGATTC CTCACCATCA AAGAATTCTT CCCTTGATGC TCCTGTGGTT CCATCTACTA CAGTGTTCTC CAGGAGAAGT CCTTCAGACA AAGATCCATC GCTAGGAGAA AGAGAAGAAA AAGACAATGC TGGGAAGAAC CAAAAGAATC AGTTTATTGT AAGCCACTCA GAAAACCAAG AGAGAAATGA TAGTCCTGTG CCTACACATG ATGAAGTGGT TGATGTCAAA TGCCATTCAC ACTCTCCTTT TAGGAATGAA AGAGGAAAAG GAAAAATAAG GCATCATATA TCCTGTATTG AAAAGTTAAG CAAAACAGAA AGTATATCAG TACCCACCAG TGATCACAGG AGCCTCATTG AAGCAAATCA AAGCAATTCC AAAGTTTCTG AACTTGACAC AATTTATTGT ACCTTGCCAA GAAAATCAAG CAGTTTTCTC ATACATGGCA GGCAGTCAGG AAGTAAAATA ATGGCTGCTT CATTGAGGAA TGGGCCACCT CCCTTCCAAA TCAAAAATAA TGTGGAAGAT GCAATGGGGA ACTATATGTT AAACAAATTT AGTCCCAGTT CTCCTGAGTC AGCGAATGAA TGTTCCAAAG TCCTTTCAGA CTCAGCCCTG GAAGCACCTG AAGCCACAGA GAGAATGACA AATGTAAAAA GCAGTGGATC TACTTCCGTT AGAAAAGGAC CACTTCCATT CCTCATCAAC AGGGCTATGT CATGTCCCTC AGGGGAGCCA CATGCCTCAA CTGGAAGAGA AGGAAGAAAA AAGCCATTGA CCTCAGGCAT GGATGCTTCT GAGCTAACAC CAAGGGCTTG GGAGAGAATC ATTAGCCCTG TGGAAAGTGA CTCATCTGTT AGAGATTGTT CTTTAACCAA AAGACAACAC CAAAAGGAAA ACTTCCAAGA ATACACTGAG AAAGAGGGTA AAATGGCTGC CTCCAGGAGA AGTGTATTTG CTCTTTCAAA TGAAGACCCT TTACCTTTTT GCTCAGACTT GTCAGGAAAA GAACGTGGGA AAACATTACA TAAAGTTAAG ACGACTAGTA CGTTTTCTGT TTCTGGTGAT GAAGATAATG TAAAATGTCT GGAGGTGGTC TCAATATATT ACACTCTACC GAGGAAACCC AGCAAAAAAT TCTGTAACCT CCTTCAACAG TATACACAAA ATACTAATTT ACTTATAGAA TCACCTCAAG TGGAGACTGA AACATTTCCT AACGCTTTAG AAAAAGACAA ACAGAATTAT TCTACACGAG AGCAGTCAGG AACACCTTCA TGTGAAAATC TAAAGATGTC CGTCAACTCT GATCAGACGC TCACCACTGA AAATATGACT GCCTTCCGAT TATCAAATAG GGGGCCCCTA GCTCCTACAT TACAGGAAAT GGCTTCTGTT GAGGCAGCTG TTTCTCTTCC TGAAGAGGAA TCTAAAGCTA GAGAGATTTT TTCAGATAAT TTAGCTAAAA CACCTCTAGG TGATTCAGAA AACAAGAAGG AAAGAGGCAA AAAGTTGCAA AGTGAAACCC TGCATACTTC ATTGATGCTT CAGAGAAAAA ATGTATCCGA AGAAAAATCT GAAAATTGTC AACAATCCAT TAATTCAAGT AACAGTGGTC CCTCTAGTCT TCCAGCTCTT TCAGAAGTTA ATATTGGAAA TTCCCAAACT AGAAGAAGTT CTTGGGAGTG TACAGGGAGT GGTAGAGCCA TTCCATTTAC TGGAAGTGGC AAGTGTCCCC AGAAAGATCA CACATCCACA GCTGTAGGTG ATGGCTCCAG TGGATCACAG CCTAGGGAAG GCAGAGGGGA CATTGGAACC AACTGCCAAA AAATGACTAA TAAAACACTT TCTCACTCAG AGAGTCAAGT CTTTGCCCTT ACTCCAGCAT TGCATAAACT ACAGCTTGGT GAGGAGACTC AGTCAGATGA ACCAAACTTA GAGAGTCTGC AGTCTGAACC AAGAGAATTA CCTCAAAGAA GTCAGGAGGC AAATATGACA GAGAGCAGGA AGGCTGAAGA TGAAATGCAG AAGTCAGCTT GGGATCAACC TTCACTTCCT GAAGGAAACA AAAATAAAAC CAACTTGGAT GACCTAGTAA AGGGGGAAAA TAGATCTTCA GTTAAACACA GATTGGCAGC CATGTCTAAA GCCAGCAGAA AATTCCCAGC TAAAGATGTA AGCCCCAGAA GACATGTAGC TACTATCTTC CCCCAAAGTG GAAGCAGATC TGGCTTTGAC CATTTATCTC TTGGCACAGT GGAGTGCAAC CCACTGTTCC CTGAGCCTAC TCCAAAATCT GCAGAGTCCA TTGGCGAAAG CAGGTTGAGT GAGAACAGAA AGCATGTGAA GAAATCCGAG AACCTTCTCC CCATTACTGT ACTACCCAAC AGAGAACCTT CTACACACGT CAGCAACCAG AAGTCTAACA GCATTTCACA ACGACATCAG AATGAGTTTA AAAACGTCTC AGAATCACCA TCAAAGCATG AGAATTCTAA AGACGTCACA GCAGCTCAGA ATTTAGTAAG AGAATCAGGA GCCCCATCAC CCATCACATT CACCAGCCTC AGGGAAGCAG AATTCTCTGA CAATCAGAGG AGGCTGAGCC CTCCTTTTCC ACTGGAGCCT GCACAGAAAT CTAGAGTAAG CAGTCCACTG GCCAGTTTTC TGCAGCAACA AAGGAGTGCT TCATCTCTGG AGTGGGAACC TGAGCCACAC CTCTATCGTT CAAAGAGTTT AAAAAGCATT AATGTTCATG GCGATCTACT ACGAAAAAGC CATCCTCCAA AAGTCAGGGA GCGCCATTTT TCTGAAAGCA CTTCTATTGA CAATGCCCTG AGTCGACTGA CCCTTGGGAA TGAATTCTCT GTCAACAATG GGTACAGTCG AAGATTCAGA TCTTTTTCTG AACTCCCCTC CTGTGATGGA AATGAAAGTT GGGCTTATCG CAGCGGGACA AAAACAGGTC CCAGGTCTGC AATATCTATA TACAGACCTA TCGACTATGG GATCTTTGGG AAAGAACAAC AGTTAGCTTT CTTAGAAAAT GTAAAGAGGT CACTTACACA AGGAAGATTA TGGAAACCAA GTTTTCTTAA GAACCCTGGC TTCCTAAAAG ATGATTTGAG GAACCCTCCC AACCCCTCAG AGTCATTAAG CTCAAATTCT CCCAGTAGTC AGGTGCCAGA AGATGGCTTA TCTCCAAGTG AACCGCTTAA TATCTATGAG GATGACCCAG TGGACTCAGA TTGTGACACA GACACAACCA CAGATGATGA ATACTACCTG GATGAAAATG ACAAAGAGTC AGAACTGTGA. It is sometimes possible for the material contained within the vial of "EXPH5, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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