DDX50 cdna clone
DDX50 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined. [provided by RefSeq, Jul 2008]
Uniprot Description
DDX50: an RNA helicase of the DEAD-box family.
Protein type: RNA-binding; Nucleolus; EC 3.6.4.13; Helicase
Chromosomal Location of Human Ortholog: 10q22.1
Cellular Component: membrane; nucleolus; plasma membrane
Molecular Function: ATP-dependent RNA helicase activity
Biological Process: RNA secondary structure unwinding
Research Articles on DDX50
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Product Notes
The DDX50 ddx50 (Catalog #AAA1275847) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcctggga aactcctctg gggggacatt atggagctgg aagcaccctt ggaggagtcc gagagccaga agaaggagag gcaaaagagt gacagaagga agtcaaggca ccattatgac tcggatgaga aatcagaaac aagagaaaat ggtgttacag atgacctgga tgctcccaag gccaaaaaat ctaaaatgaa agagaagcta aatggagaca ctgaagaagg atttaataga ctttcagatg aattctccaa atctcataag tcaagaagaa aagatctacc aaatggagat atagatgaat atgaaaaaaa atcaaagcga gtatcatctt tagatacttc tactcataaa tcaagtgata ataaactaga ggagacctta acacgtgaac agaaagaagg agccttctcc aattttccta tttctgaaga gactataaag cttctgaaag gtcgaggggt aacatatctc tttcctattc aagttaagac ctttggtcct gtatatgaag gaaaagattt aatagctcaa gcacggacag gaacaggaaa gacattctct tttgccatcc ccttaattga aagactccaa agaaatcaag aaacaattaa aaaaagccgc tcaccaaagg tacttgtttt ggctccaaca agggaactgg caaaccaagt agccaaagac ttcaaagata taactaggaa actcagcgtg gcgtgttttt atggtggaac atcatatcaa agccaaatta atcatattcg aaatggtatt gacatcttgg ttggaacacc tggtcgtatc aaagaccatc tgcagagtgg ccgattggat ctttctaaac tgcgacatgt tgtgcttgat gaagtggatc agatgttaga tttaggtttc gctgaacaag ttgaagatat tattcatgaa tcctacaaaa ctgattctga agacaatcct cagactttac ttttttctgc aacttgccca cagtgggtat acaaagttgc aaaaaaatac atgaaatcca gatatgaaca ggttgacctt gttggaaaaa tgactcaaaa ggctgcaact actgtggaac atttggccat ccagtgtcat tggtctcaga ggccagcagt tattggagat gtccttcaag tctacagtgg gtctgaaggg agggctatta ttttctgtga gaccaagaag aatgtaactg aaatggccat gaatccacac ataaaacaga atgcccagtg tttacatggg gacattgcac agtcacaaag agaaattaca ctaaaaggct tcagagaagg tagttttaaa gttttggtgg caaccaatgt ggctgcccgt ggtttggaca ttcctgaagt tgacctggtg attcaaagtt ctcctcctca ggatgttgag tcctatatcc atcgctctgg acgcacaggt agagctggac ggacagggat ttgtatatgt ttttatcaac caagagaaag aggtcaacta agatatgtgg aacaaaaagc aggaattact tttaaacgtg taggtgttcc ttctacaatg gatttagtta aatctaaaag catggatgcc atcaggtctc tggcttccgt ttcttatgct gctgttgatt ttttccgacc atcagctcag agactgatag aagagaaagg tgcagtggat gcattggctg cagctttagc ccacatttct ggtgcatcaa gctttgaacc acgatctttg atcacctctg ataaggggtt tgtgaccatg actctggaaa gcctagagga aatacaggat gtcagctgtg cttggaaaga acttaacaga aagctgagta gtaatgcagt gtctcagatt accagaatgt gcctcctgaa aggaaatatg ggtgtttgct ttgatgttcc tacaactgag tcagaaaggt tacaggcaga gtggcatgat tccgactgga tactctcagt gccagccaaa ttacctgaaa ttgaagaata ttatgatgga aacacatctt ctaattccag acagaggagt ggctggtcaa gtggtcgatc aggccggtca ggccggtcag gtggtcgatc tggcggccgg tcaggtagac agagtcgaca aggaagtcgc tcaggaagtc gacaagatgg tagaagacga agtgggaata gaaatcgatc aagaagtggg ggccacaaac ggagttttga ctga. It is sometimes possible for the material contained within the vial of "DDX50, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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