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Western Blot (WB) (HBZ Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the HBZ antibody detected the HBZ protein (arrow).)

Rabbit anti-Human HBZ Polyclonal Antibody | anti-HBZ antibody

HBZ, CT (HBZ, HBZ2, Hemoglobin subunit zeta, HBAZ, Hemoglobin zeta chain, Zeta-globin) (Biotin)

Gene Names
HBZ; HBZ1; HBZ-T1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
HBZ; Polyclonal Antibody; CT (HBZ; HBZ2; Hemoglobin subunit zeta; HBAZ; Hemoglobin zeta chain; Zeta-globin) (Biotin); Zeta-globin; anti-HBZ antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-HBZ antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
HBZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the C-terminal region of human HBZ.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(HBZ Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the HBZ antibody detected the HBZ protein (arrow).)

Western Blot (WB) (HBZ Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the HBZ antibody detected the HBZ protein (arrow).)
Product Categories/Family for anti-HBZ antibody
References
Hivin, P., et al. J. Cell. Sci. 118 (PT 7), 1355-1362 (2005): He, Z., et al. Biochem. Biophys. Res. Commun. 325(4):1376-1382(2004). Kidd, R.D., et al. Biochemistry 40(51):15669-15675(2001). Lau, E.T., et al. Prenat. Diagn. 21(7):529-539(2001). Daniels, R.J., et al. Hum. Mol. Genet. 10(4):339-352(2001).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15,637 Da
NCBI Official Full Name
hemoglobin subunit zeta
NCBI Official Synonym Full Names
hemoglobin, zeta
NCBI Official Symbol
HBZ
NCBI Official Synonym Symbols
HBZ1; HBZ-T1
NCBI Protein Information
hemoglobin subunit zeta; HBAZ; hemoglobin zeta chain; zeta-globin
UniProt Protein Name
Hemoglobin subunit zeta
Protein Family
UniProt Gene Name
HBZ
UniProt Synonym Gene Names
HBZ2
UniProt Entry Name
HBAZ_HUMAN

NCBI Description

Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'. [provided by RefSeq, Nov 2009]

Uniprot Description

HBZ: The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin, synthesized primarily in the yolk sac. Belongs to the globin family.

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: hemoglobin complex

Molecular Function: protein binding; iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: erythrocyte maturation; oxygen transport; negative regulation of transcription from RNA polymerase II promoter

Research Articles on HBZ

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Product Notes

The HBZ hbz (Catalog #AAA6305649) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HBZ, CT (HBZ, HBZ2, Hemoglobin subunit zeta, HBAZ, Hemoglobin zeta chain, Zeta-globin) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HBZ can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the HBZ hbz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HBZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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