B3GNT1 cdna clone

B3GNT1 cDNA Clone

Gene Names

B4GAT1; iGAT; iGNT; B3GNT1; B3GNT6; B3GN-T1; MDDGA13; BETA3GNTI

Synonyms

B3GNT1; B3GNT1 cDNA Clone; B3GNT1 cdna clone

Ordering
Cat. Num. AAA1269699 For Research Use Only!

Sequence

atgcagatgtcctacgccatccggtgcgccttctaccagctgctgctggccgcgctcatgctggtggcgatgctgcagctgctctacctgtcgctgctgtccggactgcacgggcaggaggagcaagaccaatattttgagttctttcccccgtccccacggtccgtggaccaggtcaaggcgcagctccgcaccgcgctggcctctggaggcgtcctggacgctagcggcgattaccgcgtctacaggggcctgctgaagaccaccatggaccccaacgatgtgatcctggccacgcacgccagcgtggacaacctgctgcacctgtcgggtctgctggagcgctgggagggcccgctgtccgtgtcggtgttcgcggccaccaaggaggaggcgcagctggccacggtgctggcctacgcgctgagcagccactgccccgacatgcgcgccagggtcgccatgcacctcgtgtgcccctcgcgttacgaggcagccgtgcccgacccccgggagccgggggagtttgccctgctgcggtcctgccaggaggtctttgacaagctagccagggtggcccagcccgggattaattatgcgctgggcaccaatgtctcctaccccaataacctgctgaggaatctggctcgtgagggggccaactatgccctggtgatcgatgtggacatggtgcccagcgaggggctgtggagaggcctgcgggaaatgctggatcagagcaaccagtggggaggcaccgcgctggtggtgcctgccttcgaaatccgaagagcccgccgcatgcccatgaacaaaaacgagctggtgcagctctaccaggttggcgaggtgcggcccttctattatgggttgtgcaccccctgccaggcacccaccaactattcccgctgggtcaacctgccggaagagagcttgctgcggcccgcctacgtggtaccttggcaggacccctgggagccattctacgtggcaggaggcaaggtgcccaccttcgacgagcgctttcggcagtacggcttcaaccgaatcagccaggcctgcgagctgcatgtggcggggtttgattttgaggtcctgaacgaaggtttcttggttcataagggcttcaaagaagcgttgaagttccatccccaaaaggaggctgaaaatcagcacaataagatcctatatcgccagttcaaacaggagttgaaggccaagtaccccaactctccccgacgctgctga

Sequence Length

1248

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

NCBI and Uniprot Product Information

NCBI GI #

33869339

NCBI GeneID

11041

Molecular Weight

47,119 Da

NCBI Official Full Name

Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1, mRNA

NCBI Official Synonym Full Names

beta-1,4-glucuronyltransferase 1

NCBI Official Symbol

B4GAT1

NCBI Official Synonym Symbols

iGAT; iGNT; B3GNT1; B3GNT6; B3GN-T1; MDDGA13; BETA3GNTI

NCBI Protein Information

beta-1,4-glucuronyltransferase 1

UniProt Protein Name

Beta-1,4-glucuronyltransferase 1

UniProt Gene Name

B4GAT1

UniProt Synonym Gene Names

iGnT

UniProt Entry Name

B4GA1_HUMAN

NCBI Description

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen. [provided by RefSeq, Jul 2008]

Uniprot Description

B4GAT1: Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Glycan Metabolism - keratan sulfate biosynthesis; EC 2.4.1.149; Transferase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: Golgi apparatus; Golgi membrane

Molecular Function: glucuronosyltransferase activity; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity

Biological Process: keratan sulfate biosynthetic process; poly-N-acetyllactosamine biosynthetic process; protein amino acid O-linked mannosylation

Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 13

Research Articles on B3GNT1

1. B4GAT1 is involved in the initiation of the LARGE-dependent repeating disaccharide that is necessary for extracellular matrix protein binding to O-mannosylated alpha-dystroglycan.

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Product Notes

The B3GNT1 b4gat1 (Catalog #AAA1269699) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcagatgt cctacgccat ccggtgcgcc ttctaccagc tgctgctggc cgcgctcatg ctggtggcga tgctgcagct gctctacctg tcgctgctgt ccggactgca cgggcaggag gagcaagacc aatattttga gttctttccc ccgtccccac ggtccgtgga ccaggtcaag gcgcagctcc gcaccgcgct ggcctctgga ggcgtcctgg acgctagcgg cgattaccgc gtctacaggg gcctgctgaa gaccaccatg gaccccaacg atgtgatcct ggccacgcac gccagcgtgg acaacctgct gcacctgtcg ggtctgctgg agcgctggga gggcccgctg tccgtgtcgg tgttcgcggc caccaaggag gaggcgcagc tggccacggt gctggcctac gcgctgagca gccactgccc cgacatgcgc gccagggtcg ccatgcacct cgtgtgcccc tcgcgttacg aggcagccgt gcccgacccc cgggagccgg gggagtttgc cctgctgcgg tcctgccagg aggtctttga caagctagcc agggtggccc agcccgggat taattatgcg ctgggcacca atgtctccta ccccaataac ctgctgagga atctggctcg tgagggggcc aactatgccc tggtgatcga tgtggacatg gtgcccagcg aggggctgtg gagaggcctg cgggaaatgc tggatcagag caaccagtgg ggaggcaccg cgctggtggt gcctgccttc gaaatccgaa gagcccgccg catgcccatg aacaaaaacg agctggtgca gctctaccag gttggcgagg tgcggccctt ctattatggg ttgtgcaccc cctgccaggc acccaccaac tattcccgct gggtcaacct gccggaagag agcttgctgc ggcccgccta cgtggtacct tggcaggacc cctgggagcc attctacgtg gcaggaggca aggtgcccac cttcgacgag cgctttcggc agtacggctt caaccgaatc agccaggcct gcgagctgca tgtggcgggg tttgattttg aggtcctgaa cgaaggtttc ttggttcata agggcttcaa agaagcgttg aagttccatc cccaaaagga ggctgaaaat cagcacaata agatcctata tcgccagttc aaacaggagt tgaaggccaa gtaccccaac tctccccgac gctgctga. It is sometimes possible for the material contained within the vial of "B3GNT1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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B3GNT1 cdna clone