ATP5G3 cdna clone
ATP5G3 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]
Uniprot Description
ATP5G3: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. Belongs to the ATPase C chain family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Energy Metabolism - oxidative phosphorylation
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component: mitochondrial outer membrane; mitochondrial proton-transporting ATP synthase complex
Biological Process: ATP biosynthetic process; mitochondrial ATP synthesis coupled proton transport
Research Articles on ATP5G3
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Product Notes
The ATP5G3 atp5g3 (Catalog #AAA1276725) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGTTCGCCT GCGCCAAGCT CGCCTGCACC CCCTCTCTGA TCCGAGCTGG ATCCAGAGTT GCATACAGAC CAATTTCTGC ATCAGTGTTA TCTCGACCAG AGGCTAGTAG GACTGGAGAG GGCTCTACGG TATTTAATGG GGCCCAGAAT GGTGTGTCTC AGCTAATCCA AAGGGAGTTT CAGACCAGTG CAATCAGCAG AGACATTGAT ACTGCTGCCA AATTTATTGG TGCAGGTGCT GCAACAGTAG GAGTGGCTGG TTCTGGTGCT GGTATTGGAA CAGTCTTTGG CAGCCTTATC ATTGGTTATG CCAGAAACCC TTCGCTGAAG CAGCAGCTGT TCTCATATGC TATCCTGGGA TTTGCCTTGT CTGAAGCTAT GGGTCTCTTT TGTTTGATGG TTGCTTTCTT GATTTTGTTT GCCATGTAA. It is sometimes possible for the material contained within the vial of "ATP5G3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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