APOBEC3H cdna clone
APOBEC3H cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Uniprot Description
APOBEC3H: DNA cytidine deaminase which may provide cellular innate resistance to a specific panel of genetic invaders including endogenous retroelements and a subset of viruses. Belongs to the cytidine and deoxycytidylate deaminase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; EC 3.5.4.-
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: cytoplasm; nucleus
Molecular Function: cytidine deaminase activity; protein binding
Biological Process: defense response to virus; negative regulation of retroviral genome replication; negative regulation of viral reproduction
Research Articles on APOBEC3H
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Product Notes
The APOBEC3H apobec3h (Catalog #AAA1278903) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggctctgt taacagccga aacattccgc ttacagttta acaacaagcg ccgcctcaga aggccttact acccgaggaa ggccctcttg tgttaccagc tgacgccgca gaatggctcc acgcccacga gaggctactt tgaaaacaag aaaaagtgcc atgcagaaat ttgctttatt aacgagatca agtccatggg actggacgaa acgcagtgct accaagtcac ctgttacctc acgtggagcc cctgctcctc ctgtgcctgg gagctggttg acttcatcaa ggctcacgac catctgaacc tgggcatctt cgcctcccgc ctgtactacc actggtgcaa gccccagcag aaggggctgc ggcttctgtg tggatcccag gtcccggtgg aggtcatggg cttcccagag tttgctgact gctgggaaaa ctttgtggac cacgagaaac cgctttcctt caacccctat aagatgttag aggagctaga taaaaacagt cgagccataa agcgacggct tgagaggata aagtcctga. It is sometimes possible for the material contained within the vial of "APOBEC3H, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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