ALG13 cdna clone
ALG13 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Uniprot Description
ALG13: Isoform 2 may be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide pathway. Belongs to the glycosyltransferase 28 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Glycan Metabolism - N-glycan biosynthesis; EC 2.4.1.141; EC 3.4.19.12; Transferase
Chromosomal Location of Human Ortholog: Xq23
Cellular Component: endoplasmic reticulum membrane
Molecular Function: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity
Biological Process: dolichol-linked oligosaccharide biosynthetic process
Disease: Congenital Disorder Of Glycosylation, Type Is
Research Articles on ALG13
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Product Notes
The ALG13 alg13 (Catalog #AAA1269916) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaagtgcg tgtttgttac cgtagggacc accagctttg acgacctcat tgcgtgtgtg tcggcgcccg acagtctgca aaaaatcgag agccttggtt acaaccgact tatcctgcaa attggtagag gaacggtggt acctgaaccc ttcagtactg agtcgtttac tctggatgtt tacaggtaca aggattcctt gaaagaagac attcagaaag cagatcttgt tattagtcac gcaggtgcag gaagctgttt ggagactctg gaaaaaggaa agccactcgt agtggttata aacgaaaagt tgatgaacaa tcatcagctg gaactggcaa agcagctaca caaagagggt catctcttct attgtacctg cagcacgctt cctgggctgt tacagtcaat ggacttatca acactgaaat gttatcctcc tggccagcca gaaaaatttt ctgcattttt ggataaagtt gttggattac aaaaataa. It is sometimes possible for the material contained within the vial of "ALG13, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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