Western Blot (WB)
(ALG13 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the ALG13 antibody detected the ALG13 protein (arrow).)
Rabbit anti-Human, mouse ALG13 Polyclonal Antibody | anti-ALG13 antibody
ALG13 Antibody (Center)
Western Blot (WB)
(ALG13 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the ALG13 antibody detected the ALG13 protein (arrow).)
Western Blot (WB)
(ALG13 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the ALG13 antibody detected the ALG13 protein (arrow).)
bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes
with asparagine-linked glycosylation 14 homolog to form a
functional UDP-GlcNAc glycosyltransferase that catalyzes the second
sugar addition of the highly conserved oligosaccharide precursor in
endoplasmic reticulum N-linked glycosylation. Multiple transcript
variants encoding different isoforms have been found for this gene.
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Gao, X.D., et al. J. Biol. Chem. 280(43):36254-36262(2005)
Epplen, C., et al. Hum. Genet. 93(1):35-41(1994)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Uniprot Description
ALG13: Isoform 2 may be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide pathway. Belongs to the glycosyltransferase 28 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.4.1.141; Transferase; EC 3.4.19.12; Glycan Metabolism - N-glycan biosynthesis
Chromosomal Location of Human Ortholog: Xq23
Cellular Component: endoplasmic reticulum membrane
Molecular Function: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity; carbohydrate binding; cysteine-type peptidase activity
Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; lipid glycosylation; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; proteolysis
Disease: Congenital Disorder Of Glycosylation, Type Is
Research Articles on ALG13
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Product Notes
The ALG13 alg13 (Catalog #AAA9208057) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 44-70. The ALG13 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ALG13 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the ALG13 alg13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALG13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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