Cyclin-Dependent Kinase 2 Associated Protein 2 Recombinant Protein | CDK2AP2 recombinant protein
Recombinant Human Cyclin-Dependent Kinase 2 Associated Protein 2
Gene Names
CDK2AP2; p14; DOC-1R
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Cyclin-Dependent Kinase 2 Associated Protein 2; Recombinant Human Cyclin-Dependent Kinase 2 Associated Protein 2; CDK2AP2 Human; Cyclin-Dependent Kinase 2 Associated Protein 2 Human Recombinant; Cyclin-dependent kinase 2-associated protein 2; CDK2-associated protein 2; DOC-1-related protein; DOC-1R; CDK2AP2; DOC1R; p14; CDK2AP2 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
CDK2AP2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT.
Sterile Filtered clear colorless solution.
Sterile Filtered clear colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSYKPIA PAPSSTPGSS TPGPGTPVPT GSVPSPSGSV PGAGAPFRPL FNDFGPPSMG YVQAMKPPGA QGSQSTYTDL LSVIEEMGKE IRPTYAGSKS AMERLKRGII HARALVRECL AETERNART
Sequence Length
126
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for CDK2AP2 recombinant protein
Description: CDK2AP2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids (1-126 a.a) and having a molecular mass of 15.5kDa.CDK2AP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Cyclin-Dependent Kinase 2 Associated Protein 2 (CDK2AP2) is a member of the CDK2AP family. CDK2-associated protein is assumed to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. CDK2AP2 is implicated in the regulation of self-renewal of stem cells during early embryogenesis. CDK2AP2 is a regulator for self-renewal of mESCs (mouse embryonic stem cells) under permissive conditions, and cell survival during differentiation of the mESCs into terminally differentiated cell types.
Introduction: Cyclin-Dependent Kinase 2 Associated Protein 2 (CDK2AP2) is a member of the CDK2AP family. CDK2-associated protein is assumed to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. CDK2AP2 is implicated in the regulation of self-renewal of stem cells during early embryogenesis. CDK2AP2 is a regulator for self-renewal of mESCs (mouse embryonic stem cells) under permissive conditions, and cell survival during differentiation of the mESCs into terminally differentiated cell types.
Product Categories/Family for CDK2AP2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13,101 Da
NCBI Official Full Name
cyclin-dependent kinase 2-associated protein 2 isoform 1
NCBI Official Synonym Full Names
cyclin-dependent kinase 2 associated protein 2
NCBI Official Symbol
CDK2AP2
NCBI Official Synonym Symbols
p14; DOC-1R
NCBI Protein Information
cyclin-dependent kinase 2-associated protein 2; CDK2-associated protein 2; DOC-1-related protein; tumor suppressor deleted in oral cancer related 1
UniProt Protein Name
Cyclin-dependent kinase 2-associated protein 2
Protein Family
UniProt Gene Name
CDK2AP2
UniProt Synonym Gene Names
DOC1R; CDK2-associated protein 2; DOC-1R
UniProt Entry Name
CDKA2_HUMAN
NCBI Description
This gene encodes a protein that interacts with cyclin-dependent kinase 2 associated protein 1. Pseudogenes associated with this gene are located on chromosomes 7 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
Uniprot Description
CDK2AP2: Belongs to the CDK2AP family.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 11q13
Research Articles on CDK2AP2
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Product Notes
The CDK2AP2 cdk2ap2 (Catalog #AAA146492) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMSY KPIA PAPSSTPGSS TPGPGTPVPT GSVPSPSGSV PGAGAPFRPL FNDFGPPSMG YVQAMKPPGA QGSQSTYTDL LSVIEEMGKE IRPTYAGSKS AMERLKRGII HARALVRECL AETERNART. It is sometimes possible for the material contained within the vial of "Cyclin-Dependent Kinase 2 Associated Protein 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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