Mouse P Cadherin ELISA Kit | CDH3 elisa kit

Mouse P Cadherin ELISA Kit

Cat. Num. AAA825052

• Gene Names: Cdh3; Cadp; Cdhp; Pcad; AI385538; P-cadherin
• Reactivity: Mouse
• Applications: ELISA
• Synonyms: P Cadherin; Mouse P Cadherin ELISA Kit; CDHP; Cadherin-3; Placental cadherin; P-cadherin; CDH3 elisa kit

• Reactivity: Mouse
• Sequence Length: 822

• Applicable Applications for CDH3 elisa kit: Sandwich ELISA (SE)
• Samples: Cell Culture Supernatants, Serum
• Assay Type: Sandwich
• Detection Range: 62.5 pg/ml - 4000 pg/ml
• Sensitivity: 10 pg/ml
• Detection Method: Colorimetric
• Preparation and Storage: Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for CDH3 elisa kit

Sandwich ELISA for quantitative detection of Mouse P Cadherin concentrations.

NCBI and Uniprot Product Information

• NCBI GI #: 83715978
• NCBI GeneID: 12560
• NCBI Accession #: NP_001032898.1
• NCBI GenBank Nucleotide #: NM_001037809.5
• UniProt Accession #: P10287; Q61465; Q8BSL6
• Molecular Weight: 90,612 Da
• NCBI Official Full Name: cadherin-3 isoform a preproprotein
• NCBI Official Synonym Full Names: cadherin 3
• NCBI Official Symbol: Cdh3
• NCBI Official Synonym Symbols: Cadp; Cdhp; Pcad; AI385538; P-cadherin
• NCBI Protein Information: cadherin-3; placental cadherin; RPE-specific cadherin
• UniProt Protein Name: Cadherin-3
• UniProt Gene Name: Cdh3
• UniProt Synonym Gene Names: Cdhp; P-cadherin
• UniProt Entry Name: CADH3_MOUSE

NCBI Description

This gene encodes a calcium-dependent cell-cell adhesion protein containing five cadherin domains. The encoded protein plays a role in epithelial outgrowth, such as that which occurs during the development of hair follicles and limb buds. Loss of function of the related gene in humans results in ectodermal dysplasia, ectrodactyly, and macular dystrophy and congential hypotrichosis with juvenile macular dystrophy. This gene is located in the vicinity of similar cadherin genes on chromosome 8. The proprotein is further cleaved into a functional chain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Uniprot Description

CDH3: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Interacts with CDCP1. Expressed in some normal epithelial tissues and in some carcinoma cell lines. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion

Cellular Component: cell-cell adherens junction; membrane; cytoplasm; integral to membrane; plasma membrane

Molecular Function: metal ion binding; calcium ion binding

Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; negative regulation of transforming growth factor-beta2 production; retinal homeostasis; hair cycle process; cell-cell adhesion; positive regulation of monophenol monooxygenase activity; negative regulation of catagen; keratinization; positive regulation of melanin biosynthetic process; Wnt receptor signaling pathway through beta-catenin; cell adhesion; homophilic cell adhesion