SDS-Page
(Recombinant Human Cadherin-17/LI-cadherin/CDH17 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 105-115 kDa.)
Cadherin-17/LI-cadherin/CDH17 Recombinant Protein | CDH17 recombinant protein
Recombinant Human Cadherin-17/LI-cadherin/CDH17 Protein
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
SDS-Page
(Recombinant Human Cadherin-17/LI-cadherin/CDH17 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 105-115 kDa.)
SDS-Page
(Recombinant Human Cadherin-17/LI-cadherin/CDH17 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 105-115 kDa.)
Background: This protein is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Uniprot Description
CDH17: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 8q22.1
Cellular Component: basolateral plasma membrane; integral to membrane; plasma membrane
Molecular Function: transporter activity; calcium ion binding; proton-dependent oligopeptide secondary active transmembrane transporter activity
Biological Process: intercellular junction assembly and maintenance; transport; calcium-dependent cell-cell adhesion; oligopeptide transport; homophilic cell adhesion; cell adhesion
Research Articles on CDH17
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Product Notes
The CDH17 cdh17 (Catalog #AAA9139705) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: QEGKFSGPLK PMTFSIYEGQ EPSQIIFQFK ANPPAVTFEL TGETDNIFVI EREGLLYYNR ALDRETRSTH NLQVAALDAN GIIVEGPVPI TIKVKDINDN RPTFLQSKYE GSVRQNSRPG KPFLYVNATD LDDPATPNGQ LYYQIVIQLP MINNVMYFQI NNKTGAISLT REGSQELNPA KNPSYNLVIS VKDMGGQSEN SFSDTTSVDI IVTENIWKAP KPVEMVENST DPHPIKITQV RWNDPGAQYS LVDKEKLPRF PFSIDQEGDI YVTQPLDREE KDAYVFYAVA KDEYGKPLSY PLEIHVKVKD INDNPPTCPS PVTVFEVQEN ERLGNSIGTL TAHDRDEENT ANSFLNYRIV EQTPKLPMDG LFLIQTYAGM LQLAKQSLKK QDTPQYNLTI EVSDKDFKTL CFVQINVIDI NDQIPIFEKS DYGNLTLAED TNIGSTILTI QATDADEPFT GSSKILYHII KGDSEGRLGV DTDPHTNTGY VIIKKPLDFE TAAVSNIVFK AENPEPLVFG VKYNASSFAK FTLIVTDVNE APQFSQHVFQ AKVSEDVAIG TKVGNVTAKD PEGLDISYSL RGDTRGWLKI DHVTGEIFSV APLDREAGSP YRVQVVATEV GGSSLSSVSE FHLILMDVND NPPRLAKDYT GLFFCHPLSA PGSLIFEATD DDQHLFRGPH FTFSLGSGSL QNDWEVSKIN GTHARLSTRH TEFEEREYVV LIRINDGGRP PLEGIVSLPV TFCSCVEGSC FRPAGHQTGI PTVGM. It is sometimes possible for the material contained within the vial of "Cadherin-17/LI-cadherin/CDH17, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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