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CD93 recombinant protein

Recombinant Mouse CD93

Gene Names
Cd93; Ly68; AA4.1; C1qr1; C1qrp; AA145088; AW555904; 6030404G09Rik
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
CD93; Recombinant Mouse CD93; CD93 Mouse; CD93 Mouse Recombinant; C1q/MBL/SPA receptor; C1qR(p); C1qRp; Cell surface antigen AA4; Complement; component 1 q subcomponent receptor 1; Lymphocyte antigen 68; Ly-68; Cd93; CD93 recombinant protein
Ordering
For Research Use Only!
Host
Sf9 Insect Cells
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
CD93 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Sterile filtered colorless solution.
Sequence
ADSQAVVCEG TACYTAHWGK LSAAEAQHRC NENGGNLATV KSEEEARHVQ QALTQLLKTK APLEAKMGKF WIGLQREKGN CTYHDLPMRG FSWVGGGEDT AYSNWYKASK SSCIFKRCVS LILDLSLTPH PSHLPKWHES PCGTPEAPGN SIEGFLCKFN FKGMCRPLAL GGPGRVTYTT PFQATTSSLE AVPFASVANV ACGDEAKSET HYFLCNEKTP GIFHWGSSGP LCVSPKFGCS FNNGGCQQDC FEGGDGSFRC GCRPGFRLLD DLVTCASRNP CSSNPCTGGG MCHSVPLSEN YTCRCPSGYQ LDSSQVHCVD IDECQDSPCA QDCVNTLGSF HCECWVGYQP SGPKEEACED VDECAAANSP CAQGCINTDG SFYCSCKEGY IVSGEDSTQC EDIDECSDAR GNPCDSLCFN TDGSFRCGCP PGWELAPNGV FCSRGTVFSE LPARPPQKED NDDRKESTMP PTEMPSSPSG SKDVSNRAQT TGLFVQSDIP TASVPLEIEI PSEVSDVWFE LGTYLPTTSG HSKPTHEDSV SAHSDTDGQN LEHHHHHH
Sequence Length
644
Related Product Information for CD93 recombinant protein
Introduction: CD93, is a receptor or else an element of a larger receptor complex for C1q, MBL2-mannose-binding lectin and SPA-pulmonary surfactant protein A. CD93 mediates the enhancement of phagocytosis in monocytes as well as macrophages upon interaction with soluble defense collagens. CD93 takes part in the intercellular adhesion. Furthermore, CD93 was expressed on (pre) plasmablasts/plasma cells, including long-lived plasma cells which demonstrated decreased cell cycle activity, high levels of isotype-switched Ig secretion, as well as modification of the transcriptional network. CD93 is vital for the maintenance of plasma cells in bone marrow niches.

Description: CD93 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 558 amino acids (23-572a.a.) and having a molecular mass of 60.1kDa. (Molecular size on SDS-PAGE will appear at approximately 70-100kDa).CD93 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Product Categories/Family for CD93 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
69,354 Da
NCBI Official Full Name
complement component C1q receptor
NCBI Official Synonym Full Names
CD93 antigen
NCBI Official Symbol
Cd93
NCBI Official Synonym Symbols
Ly68; AA4.1; C1qr1; C1qrp; AA145088; AW555904; 6030404G09Rik
NCBI Protein Information
complement component C1q receptor
UniProt Protein Name
Complement component C1q receptor
UniProt Gene Name
Cd93
UniProt Synonym Gene Names
Aa4; C1qr1; C1qrp; Ly68; C1qR(p); C1qRp; Ly-68
UniProt Entry Name
C1QR1_MOUSE

Uniprot Description

CD93: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.

Protein type: Cell adhesion; Membrane protein, integral

Cellular Component: cell surface; cytoplasmic vesicle; extracellular matrix; plasma membrane

Molecular Function: complement component C1q binding

Biological Process: cell-cell adhesion

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Product Notes

The CD93 cd93 (Catalog #AAA140781) is a Recombinant Protein produced from Sf9 Insect Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ADSQAVVCEG TACYTAHWGK LSAAEAQHRC NENGGNLATV KSEEEARHVQ QALTQLLKTK APLEAKMGKF WIGLQREKGN CTYHDLPMRG FSWVGGGEDT AYSNWYKASK SSCIFKRCVS LILDLSLTPH PSHLPKWHES PCGTPEAPGN SIEGFLCKFN FKGMCRPLAL GGPGRVTYTT PFQATTSSLE AVPFASVANV ACGDEAKSET HYFLCNEKTP GIFHWGSSGP LCVSPKFGCS FNNGGCQQDC FEGGDGSFRC GCRPGFRLLD DLVTCASRNP CSSNPCTGGG MCHSVPLSEN YTCRCPSGYQ LDSSQVHCVD IDECQDSPCA QDCVNTLGSF HCECWVGYQP SGPKEEACED VDECAAANSP CAQGCINTDG SFYCSCKEGY IVSGEDSTQC EDIDECSDAR GNPCDSLCFN TDGSFRCGCP PGWELAPNGV FCSRGTVFSE LPARPPQKED NDDRKESTMP PTEMPSSPSG SKDVSNRAQT TGLFVQSDIP TASVPLEIEI PSEVSDVWFE LGTYLPTTSG HSKPTHEDSV SAHSDTDGQN LEHHHHH H. It is sometimes possible for the material contained within the vial of "CD93, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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