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Human HLA class II histocompatibility antigen gamma chain ELISA Kit | CD74 elisa kit

Human HLA class II histocompatibility antigen gamma chain ELISA Kit

Gene Names
CD74; II; DHLAG; HLADG; Ia-GAMMA
Reactivity
Human
Synonyms
HLA class II histocompatibility antigen gamma chain; Human HLA class II histocompatibility antigen gamma chain ELISA Kit; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD74; DHLAG; CD74 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Samples
Serum, plasma, tissue homogenates and other biological fluids.
Detection Range
0.625-40 ng/mL
Sensitivity
Less than 0.156ng/mL
Assay Time
3-5h
Sample Volume
100T
Detection Wavelength
450 nm
Preparation and Storage
Store at 4 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
972
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,328 Da
NCBI Official Full Name
HLA class II histocompatibility antigen gamma chain isoform c
NCBI Official Synonym Full Names
CD74 molecule
NCBI Official Symbol
CD74
NCBI Official Synonym Symbols
II; DHLAG; HLADG; Ia-GAMMA
NCBI Protein Information
HLA class II histocompatibility antigen gamma chain
UniProt Protein Name
HLA class II histocompatibility antigen gamma chain
UniProt Gene Name
CD74
UniProt Synonym Gene Names
DHLAG; Ii

NCBI Description

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Uniprot Description

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Research Articles on CD74

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Product Notes

The Human CD74 cd74 (Catalog #AAA9427100) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9427100 ELISA Kit recognizes Human CD74. It is sometimes possible for the material contained within the vial of "HLA class II histocompatibility antigen gamma chain, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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